| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 29840.m000615 |
| Family | GT47 |
| Protein Properties | Length: 452 Molecular Weight: 51678 Isoelectric Point: 7.5209 |
| Chromosome | Chromosome/Scaffold: 29840 Start: 174964 End: 178621 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 65 | 376 | 0 |
| KVKIFMYDLPKKFTTGIIQQHALARGSKDTSNVKYPGHQHMGEWYLFSDLNRPEHGRIGSPVVKVDDPDEADLFYVPVFSSLSLIVNPVRPAGTEPGLVQ HYSDEEMQEQLVEWLEQQEYWKRNNGRDHVIIAGDPNALYRVLDRVKNAILLLSDFGRVRPDQGSLVKDIIVPYSHRINVYNGDIGVRDRNTLLFFMGNR YRKDGGKIRDLLFQMLESEEDVVIKHGTQSRENRRAASRGMHTSKFCLNPAGDTPSACRLFDSIVSLCVPVIVSDSIELPFEDVIDYTKIAIFVETTDSL KPGYLVKLLREV | |||
| Full Sequence |
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| Protein Sequence Length: 452 Download |
| MARKSSLLKQ TLIFSICLIL ALYAVFNTFF NPTTSSLLYP SPEDNSLSGF PGKVTENNDN 60 NNINKVKIFM YDLPKKFTTG IIQQHALARG SKDTSNVKYP GHQHMGEWYL FSDLNRPEHG 120 RIGSPVVKVD DPDEADLFYV PVFSSLSLIV NPVRPAGTEP GLVQHYSDEE MQEQLVEWLE 180 QQEYWKRNNG RDHVIIAGDP NALYRVLDRV KNAILLLSDF GRVRPDQGSL VKDIIVPYSH 240 RINVYNGDIG VRDRNTLLFF MGNRYRKDGG KIRDLLFQML ESEEDVVIKH GTQSRENRRA 300 ASRGMHTSKF CLNPAGDTPS ACRLFDSIVS LCVPVIVSDS IELPFEDVID YTKIAIFVET 360 TDSLKPGYLV KLLREVTSER ILEYQKELKK VTRYFEYDNS NGTVNEIWRQ VAQKLPLIRL 420 MTNRDRRLVK RDWSQPDCSC LCTNQTGLII SL 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-72 | 65 | 376 | 323 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
