| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 29840.m000625 |
| Family | CE1 |
| Protein Properties | Length: 255 Molecular Weight: 28515 Isoelectric Point: 5.3131 |
| Chromosome | Chromosome/Scaffold: 29840 Start: 421190 End: 425705 |
| Description | S-formylglutathione hydrolase |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| CE1 | 15 | 252 | 0 |
| DTDISILYFLSGLTCTDENFIIKSGAQRAASSEGVALIAPDTSPRGLNVEGEADSWDFGVGAGFYLNATQEKWKNWRMYDYVVKELPKLLSDNFPQLDTS RASLSGHSMGGHGALTIYLKNLDKYKSVSAFAPISNPINCPWGQKAFTNYLGSSKGDWEEYDATSLVSKFHDVSATILIDQGEDDKFLHDKQLLPQKFEE ACRSANVPLLLRMQPGYDHSYFFISTFIDDHIRHHAQA | |||
| Full Sequence |
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| Protein Sequence Length: 255 Download |
| MKSVAQRCLE DTIKDTDISI LYFLSGLTCT DENFIIKSGA QRAASSEGVA LIAPDTSPRG 60 LNVEGEADSW DFGVGAGFYL NATQEKWKNW RMYDYVVKEL PKLLSDNFPQ LDTSRASLSG 120 HSMGGHGALT IYLKNLDKYK SVSAFAPISN PINCPWGQKA FTNYLGSSKG DWEEYDATSL 180 VSKFHDVSAT ILIDQGEDDK FLHDKQLLPQ KFEEACRSAN VPLLLRMQPG YDHSYFFIST 240 FIDDHIRHHA QALNL |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam00326 | Peptidase_S9 | 0.0001 | 44 | 234 | 205 | + Prolyl oligopeptidase family. | ||
| pfam00756 | Esterase | 1.0e-47 | 21 | 248 | 240 | + Putative esterase. This family contains Esterase D. However it is not clear if all members of the family have the same function. This family is related to the pfam00135 family. | ||
| COG0627 | COG0627 | 7.0e-81 | 15 | 255 | 265 | + Predicted esterase [General function prediction only] | ||
| TIGR02821 | fghA_ester_D | 3.0e-123 | 14 | 253 | 241 | + S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well [Cellular processes, Detoxification]. | ||
| PLN02442 | PLN02442 | 0 | 15 | 255 | 241 | + S-formylglutathione hydrolase | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004091 | carboxylesterase activity |
| GO:0016023 | cytoplasmic membrane-bounded vesicle |
| GO:0018738 | S-formylglutathione hydrolase activity |
| Annotations - PDB Download unfiltered results here | |||||||
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| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3fcx_B | 0 | 21 | 254 | 48 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3fcx_A | 0 | 21 | 254 | 48 | 281 | A Chain A, Crystal Structure Of Human Esterase D |
| PDB | 3s8y_A | 0 | 18 | 254 | 47 | 279 | A Chain A, Bromide Soaked Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_B | 0 | 18 | 254 | 47 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| PDB | 3i6y_A | 0 | 18 | 254 | 47 | 279 | A Chain A, Structure Of An Esterase From The Oil-Degrading Bacterium Oleispira Antarctica |
| Hydropathy |
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| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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