| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 29864.m001461 |
| Family | GH89 |
| Protein Properties | Length: 360 Molecular Weight: 41597 Isoelectric Point: 6.4416 |
| Chromosome | Chromosome/Scaffold: 29864 Start: 548350 End: 550611 |
| Description | alpha-N-acetylglucosaminidase family / NAGLU family |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
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| Family | Start | End | Evalue |
| GH89 | 1 | 355 | 0 |
| MYGILDSISTGPIEARVSENSTMVGVGMCMEGIEHNPVVYELMSEMAFRSEKVQVLEWLKTYSRRRYGKAVHQVEAAWEILYHTIYNCTDGIADHNTDFI VKFPDWDPSVQSGSDTSQQDNKHIFLHRSGSRRFLFEGPNSTLPQAHIWYSIQKVINALQLFIDGGSHLTGSLTYRYDLVDLTRQVLSKLANQVYVDAII AFRSNDARALNLHSQKFIQLIKDIDVLLASDDNFLIGTWLESAKELALNPSEMRQYEWNARTQVTMWYDTTKTNQSKLHDYANKFWSGLLEDYYLPRAST YFDHLVKSLKQNEKFKLQEWREKWIAFSNEWQAGTKLYPMKGSGDDALAISKALY | |||
| Full Sequence |
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| Protein Sequence Length: 360 Download |
| MYGILDSIST GPIEARVSEN STMVGVGMCM EGIEHNPVVY ELMSEMAFRS EKVQVLEWLK 60 TYSRRRYGKA VHQVEAAWEI LYHTIYNCTD GIADHNTDFI VKFPDWDPSV QSGSDTSQQD 120 NKHIFLHRSG SRRFLFEGPN STLPQAHIWY SIQKVINALQ LFIDGGSHLT GSLTYRYDLV 180 DLTRQVLSKL ANQVYVDAII AFRSNDARAL NLHSQKFIQL IKDIDVLLAS DDNFLIGTWL 240 ESAKELALNP SEMRQYEWNA RTQVTMWYDT TKTNQSKLHD YANKFWSGLL EDYYLPRAST 300 YFDHLVKSLK QNEKFKLQEW REKWIAFSNE WQAGTKLYPM KGSGDDALAI SKALYDKYFG 360 |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam05089 | NAGLU | 2.0e-16 | 1 | 52 | 52 | + Alpha-N-acetylglucosaminidase (NAGLU) tim-barrel domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This central domain has a tim barrel fold. | ||
| pfam12972 | NAGLU_C | 1.0e-104 | 57 | 358 | 302 | + Alpha-N-acetylglucosaminidase (NAGLU) C-terminal domain. Alpha-N-acetylglucosaminidase, a lysosomal enzyme required for the stepwise degradation of heparan sulfate. Mutations on the alpha-N-acetylglucosaminidase (NAGLU) gene can lead to Mucopolysaccharidosis type IIIB (MPS IIIB; or Sanfilippo syndrome type B) characterized by neurological dysfunction but relatively mild somatic manifestations. The structure shows that the enzyme is composed of three domains. This C-terminal domain has an all alpha helical fold. | ||
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2vcc_A | 4e-33 | 13 | 358 | 558 | 877 | A Chain A, Peanut Peroxidase |
| PDB | 2vcb_A | 4e-33 | 13 | 358 | 558 | 877 | A Chain A, Peanut Peroxidase |
| PDB | 2vca_A | 4e-33 | 13 | 358 | 558 | 877 | A Chain A, Peanut Peroxidase |
| PDB | 2vc9_A | 4e-33 | 13 | 358 | 558 | 877 | A Chain A, Family 89 Glycoside Hydrolase From Clostridium Perfringens In Complex With 2-Acetamido-1,2-Dideoxynojirmycin |
| PDB | 4a4a_A | 1e-32 | 13 | 358 | 581 | 900 | A Chain A, Cpgh89 (E483q, E601q), From Clostridium Perfringens, In Complex With Its Substrate Glcnac-Alpha-1,4-Galactose |
| Hydropathy |
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| Sequence Alignments (This image is cropped. Click for full image.) |
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