Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 29912.m005465 |
Family | GT47 |
Protein Properties | Length: 676 Molecular Weight: 77502.2 Isoelectric Point: 9.3078 |
Chromosome | Chromosome/Scaffold: 29912 Start: 1247241 End: 1250943 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 344 | 627 | 0 |
ERTLKVYIYKDGKKPIFHLPIMKGLYASEGWFMKLMQGNKHFLVKDPRRAHLFYMPFSSRMLEYTLYVRNSHNRTNLRQYLKDYSEKIAAKYPFWNRTDG ADHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDISLPETYVRSARNPLRDLGGKPPSQRHILAFYAGSMHGYLRPILLKYWKDKDPSMKIFG PMPPGVASKMNYIQHMKSSKYCICPKGYEVNSPRVVEAIFYECVPVIISDNFVPPFFEVFNWGAFSLILAEKDIPNLKEILLSI |
Full Sequence |
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Protein Sequence Length: 676 Download |
MELRFQFHKL CQIETRKWLL VVGAVAVTHI LFQFLLLPYG NALRSLLPNS SDPIYDKSSF 60 PIIQSSTKSV MVRNPLTVDT SSLSKDSMLV KDAGLVGGSG DLKRNREDTV NGFVSDDEEL 120 DNPIELAVDN DGFVSDEEDL DNTIEFVVDR NVDDDFPDSN GTSTLQIIKI QESISSSLES 180 ITEAERDNEI LISNIVSGDT TLPQKELGHA NISFKSPPAV AQALALPINV TNLRSSGNSS 240 LGSAILKNSF ATSKNVSAKP VKKKMRCDMP PKSITLIHEM NQILVRHRRS SRATRPRWSS 300 QRDREILAAR MQIENAPHAV NDQDLYAPLF RNISKFKRSY ELMERTLKVY IYKDGKKPIF 360 HLPIMKGLYA SEGWFMKLMQ GNKHFLVKDP RRAHLFYMPF SSRMLEYTLY VRNSHNRTNL 420 RQYLKDYSEK IAAKYPFWNR TDGADHFLVA CHDWAPYETR HHMEHCIKAL CNADVTAGFK 480 IGRDISLPET YVRSARNPLR DLGGKPPSQR HILAFYAGSM HGYLRPILLK YWKDKDPSMK 540 IFGPMPPGVA SKMNYIQHMK SSKYCICPKG YEVNSPRVVE AIFYECVPVI ISDNFVPPFF 600 EVFNWGAFSL ILAEKDIPNL KEILLSIPEE KYLEMQLGVR KVQKHFLWHP SPMKYDLFYM 660 TLHAIWYNRV YQIKPR |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-61 | 343 | 627 | 306 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |