Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30005.m001275 |
Family | GT47 |
Protein Properties | Length: 507 Molecular Weight: 57651.1 Isoelectric Point: 8.9721 |
Chromosome | Chromosome/Scaffold: 30005 Start: 285034 End: 287501 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 174 | 455 | 0 |
EKQFKIYVYEEGGPPMYHDGPCKSIYSSEGRFIHELEKGKLYRTLDPDEALVYFLPFSVVMMVEYLYVPDSHETNAIGRAIVDYIHVISNKHPFWNRSLG ADHFMLSCHDWGPRASSYVPHLFNSSIRVLCNANTSEGFNPSKDASFPEIHLKTGEISGLLGGVSPSRRSILAFFAGRLHGHIRQILLEQWKNKDEDVQV YDQMPNGVSYESMLKTSRFCLCPSGYEVASPRIVEAIYTECVPVLISDNYVPPFSDVLNWKAFSVQIQVRDIPKIKEILMGI |
Full Sequence |
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Protein Sequence Length: 507 Download |
MRPPIKPISS TSSKPSLRPP SFFVLIVIVP LILISVVVLT LIPEGSSWAS LPSPDTWRVG 60 FFSSHPSLSA SYTTVNSSYA GSSIVKERSP LGREQETSNV KESDEGVINA TVKVVKRYSR 120 LEKLEASLAR VRSSIREAAQ VRNLSSVHDD PDYVPQGPVY RNANAFHRSY LEMEKQFKIY 180 VYEEGGPPMY HDGPCKSIYS SEGRFIHELE KGKLYRTLDP DEALVYFLPF SVVMMVEYLY 240 VPDSHETNAI GRAIVDYIHV ISNKHPFWNR SLGADHFMLS CHDWGPRASS YVPHLFNSSI 300 RVLCNANTSE GFNPSKDASF PEIHLKTGEI SGLLGGVSPS RRSILAFFAG RLHGHIRQIL 360 LEQWKNKDED VQVYDQMPNG VSYESMLKTS RFCLCPSGYE VASPRIVEAI YTECVPVLIS 420 DNYVPPFSDV LNWKAFSVQI QVRDIPKIKE ILMGISQRQY LRMQRRLKQV QRHFVVNGPP 480 KRFDMFHMTI HSIWLRRLNI HIQDLSN |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-63 | 173 | 455 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |