Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30065.m001138 |
Family | GT47 |
Protein Properties | Length: 498 Molecular Weight: 57493.4 Isoelectric Point: 8.2261 |
Chromosome | Chromosome/Scaffold: 30065 Start: 318128 End: 319624 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 75 | 413 | 0 |
SCSGRYIYVHDLPRRFNDLVVENCTALYRFYDMCPFLTNSGFGVKVTEGIISGRNWFATNQFLLEVIFRTRMNNYECLTNDSSLASAIFVPYYGGLDVGR YLWDYNISRDTLGADLVKWLAQKPEWKKLLGRDHFFVSGRIGWDFRRHVDNDNGWGSNLMSLPESMNMTMLTIESTAWSNEFAVPYPTHFHPSSETEVIE WQNKMRKQKRHYLFSFAGAPRPFLQDSIRSEIINQCLGSKRLCKLLNCDSGPNKCDNPVEVIKVFQDSVFCLQPPGDSYTRRSTFDSIVAGCIPVFFHPG SAYAQYEWYLPNDYTTYSVFIPGNLVKNGSISINETLLQ |
Full Sequence |
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Protein Sequence Length: 498 Download |
MEKSKIRHNR LWFVILIMFS FLFLFLYAYD YSPFSNDYET NGLASKLKHS ANAFSTQKSN 60 YNSLDDSDPK SYSDSCSGRY IYVHDLPRRF NDLVVENCTA LYRFYDMCPF LTNSGFGVKV 120 TEGIISGRNW FATNQFLLEV IFRTRMNNYE CLTNDSSLAS AIFVPYYGGL DVGRYLWDYN 180 ISRDTLGADL VKWLAQKPEW KKLLGRDHFF VSGRIGWDFR RHVDNDNGWG SNLMSLPESM 240 NMTMLTIEST AWSNEFAVPY PTHFHPSSET EVIEWQNKMR KQKRHYLFSF AGAPRPFLQD 300 SIRSEIINQC LGSKRLCKLL NCDSGPNKCD NPVEVIKVFQ DSVFCLQPPG DSYTRRSTFD 360 SIVAGCIPVF FHPGSAYAQY EWYLPNDYTT YSVFIPGNLV KNGSISINET LLQVPNDKIT 420 KMRGEVIKLI PNILYANPKS KLESLEDAFD IAIKGVLARV EKVRKEIREG KDPGIGFAEP 480 NWKLKFSRMG QQDWSRFF |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-66 | 75 | 414 | 354 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |