Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30073.m002257 |
Family | GT47 |
Protein Properties | Length: 507 Molecular Weight: 58012.9 Isoelectric Point: 9.4761 |
Chromosome | Chromosome/Scaffold: 30073 Start: 471441 End: 475973 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 119 | 424 | 0 |
IRVYVYEMPNKFTYDLLWLFRNTYRDTVNLTSNGSPVHRLIEQHSIDYWLWADLIAPETERLLKSVVRVYRQEEADLFYIPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSGGRDHILPVHHPWSFKSVRRYVKNAIWLLPDMDSTGNWYKPGQVFLEKDLILPYVPNVDLCDAKCASENESKRTTLLFFRGRLK RNAGGKIRAKLVAELSGAEGVVVEEGTAGEGGKAAAQTGMRKSIFCLSPAGDTPSSARLFDAIVSGCIPVIVSDELELPFEGILDYRKIAVFVSSSDAIQ PGWLIK |
Full Sequence |
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Protein Sequence Length: 507 Download |
MANKLHHMMI SSTRSRSPIL LFTLSLLAFS LLFFLFSLSS SQTHNPYPSP NFTLKPVTSF 60 LASLELFLTK KSLSSSSSHR DDTVREVIED DLHRLDEKMF AKESARLYSD PYYPLQFPIR 120 VYVYEMPNKF TYDLLWLFRN TYRDTVNLTS NGSPVHRLIE QHSIDYWLWA DLIAPETERL 180 LKSVVRVYRQ EEADLFYIPF FTTISFFLLE KQQCKALYRE ALKWVTDQPA WKRSGGRDHI 240 LPVHHPWSFK SVRRYVKNAI WLLPDMDSTG NWYKPGQVFL EKDLILPYVP NVDLCDAKCA 300 SENESKRTTL LFFRGRLKRN AGGKIRAKLV AELSGAEGVV VEEGTAGEGG KAAAQTGMRK 360 SIFCLSPAGD TPSSARLFDA IVSGCIPVIV SDELELPFEG ILDYRKIAVF VSSSDAIQPG 420 WLIKFLKDVS PAQTREMQRN LVKYSRHFLY SSPAQPLGPE DLVWRMMAGK LVNIKLHTRR 480 SQRVVKESRS VCTCDCKRAN FTGPTFI |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-59 | 118 | 418 | 309 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |