| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 30128.m008565 |
| Family | GT47 |
| Protein Properties | Length: 253 Molecular Weight: 28629 Isoelectric Point: 6.1276 |
| Chromosome | Chromosome/Scaffold: 30128 Start: 2524777 End: 2525844 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 17 | 181 | 0 |
| RATLVQTFGQRNHVCLNEGSITIPPYAPPQKMQARQIPPETPRSIFVYFRGLFYDVNNDPEGGYYARGARAAVWENFKNNPLFDISTEHPTTYYEDMQRA IFCLCPLGWAPWSPRLVEAVVFGCIPVIIADDIVLPFADAIPWEEIGVFVAEEDVPNLDTILTSI | |||
| Full Sequence |
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| Protein Sequence Length: 253 Download |
| MQEEKAIERG IFPLLQRATL VQTFGQRNHV CLNEGSITIP PYAPPQKMQA RQIPPETPRS 60 IFVYFRGLFY DVNNDPEGGY YARGARAAVW ENFKNNPLFD ISTEHPTTYY EDMQRAIFCL 120 CPLGWAPWSP RLVEAVVFGC IPVIIADDIV LPFADAIPWE EIGVFVAEED VPNLDTILTS 180 IPTQVVLRKQ RLLANPSMKR AMLFPQPAQS GDAFHQILNG LARKLPHDNS IYLKPGEKVL 240 NWTAGPVKDL KPW |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 5.0e-39 | 23 | 181 | 165 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAX33320.1 | 0 | 2 | 253 | 161 | 412 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
| RefSeq | NP_174064.1 | 0 | 2 | 253 | 161 | 412 | GUT2; catalytic/ glucuronoxylan glucuronosyltransferase [Arabidopsis thaliana] |
| RefSeq | XP_002297880.1 | 0 | 2 | 253 | 161 | 412 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002304637.1 | 0 | 2 | 253 | 162 | 413 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002512677.1 | 0 | 1 | 253 | 1 | 253 | catalytic, putative [Ricinus communis] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| CO499349 | 252 | 2 | 253 | 0 |
| DW117895 | 252 | 2 | 253 | 0 |
| FQ432722 | 252 | 2 | 253 | 0 |
| DV992459 | 252 | 2 | 253 | 0 |
| ES900637 | 252 | 2 | 253 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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