y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30128.m008728 |
Family | GT47 |
Protein Properties | Length: 434 Molecular Weight: 50167.4 Isoelectric Point: 7.2417 |
Chromosome | Chromosome/Scaffold: 30128 Start: 703682 End: 706283 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 56 | 359 | 0 |
LKVYMYDLPRRFHVGMMDHGGDAKNDTPVTGENLPTWPKNSGLRKQHSVEYWLMASLLYEGADEREAVRVLDPEKADAFFVPFFSSLSFNTHGHTMTDPE TEIDRQLQVDVIDMLYKSKYWQKSGGRDHVIPMTHPNAFRFLRQQLNASILIVADFGRYPKSMSTLSKDVVAPYVHVVDSFTDDEVSNPFESRTTLLFFR GNTIRKDEGKVRAKLAKILTGYDDIHFERSSATAETIKASTEGMRSSKFCLHPAGDTPSSCRLFDAIVSHCVPVIVSDQIELPYEDEIDYSQFSVFFSVN EAIQ |
Full Sequence |
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Protein Sequence Length: 434 Download |
MYGKIIVSIT FIFLMLFCYS IFIGTLDMRS YFFPLLQQQQ SPTTGARSLC ATGPPLKVYM 60 YDLPRRFHVG MMDHGGDAKN DTPVTGENLP TWPKNSGLRK QHSVEYWLMA SLLYEGADER 120 EAVRVLDPEK ADAFFVPFFS SLSFNTHGHT MTDPETEIDR QLQVDVIDML YKSKYWQKSG 180 GRDHVIPMTH PNAFRFLRQQ LNASILIVAD FGRYPKSMST LSKDVVAPYV HVVDSFTDDE 240 VSNPFESRTT LLFFRGNTIR KDEGKVRAKL AKILTGYDDI HFERSSATAE TIKASTEGMR 300 SSKFCLHPAG DTPSSCRLFD AIVSHCVPVI VSDQIELPYE DEIDYSQFSV FFSVNEAIQP 360 GYMVDQLRQL PKERWLEMWR KLKSISHHFE FQYPPEKEDA VDMLWREVKH KLPGAQLAVH 420 RSRRLKIQDW WQRR 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 1.0e-72 | 54 | 359 | 314 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAC18793.1 | 0 | 1 | 412 | 1 | 440 | End is cut off [Arabidopsis thaliana] |
RefSeq | NP_176908.2 | 0 | 1 | 431 | 1 | 429 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002272591.1 | 0 | 27 | 434 | 27 | 429 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002311068.1 | 0 | 55 | 431 | 1 | 380 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002512333.1 | 0 | 1 | 434 | 1 | 434 | catalytic, putative [Ricinus communis] |