Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30138.m004079 |
Family | GT47 |
Protein Properties | Length: 490 Molecular Weight: 55766.1 Isoelectric Point: 9.1194 |
Chromosome | Chromosome/Scaffold: 30138 Start: 1689833 End: 1692113 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 112 | 429 | 0 |
LKVYMYDMPPEFHFGLLGWKGKANQIWPNVDDLDHIPLYPGGLNLQHSIEYWLTLDLLASNRPKVVRPCGAVRVDNSSQADIIFVPYFSSLSYNRHSKLH GKEKVSMNKMLQNRLVEFLMGQDEWKRSGGRDHLIVAHHPNSMLDARKMLGAAMFVLADFGRYPVEIANLKKDVIAPYKHVVRTIPSGESAQFEERPILV FFQGAIYRKDGGIIRQELYYLLKDEKDVHFTFGTVRKNGVNKAGQGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDDIELPFEDVLDYSEFSVFV RASDAVKEGYLLNLLQSI |
Full Sequence |
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Protein Sequence Length: 490 Download |
MSEKSRLSSR FLFFLIPISM FLFIIFSVSL LQLSSTSFLP SSVIKLILVN STSIYLKSNV 60 KNELGKFPFF SSKPSQDTRS SMRSGGENCS NFEVAASGKH IGNTCNPNQG LLKVYMYDMP 120 PEFHFGLLGW KGKANQIWPN VDDLDHIPLY PGGLNLQHSI EYWLTLDLLA SNRPKVVRPC 180 GAVRVDNSSQ ADIIFVPYFS SLSYNRHSKL HGKEKVSMNK MLQNRLVEFL MGQDEWKRSG 240 GRDHLIVAHH PNSMLDARKM LGAAMFVLAD FGRYPVEIAN LKKDVIAPYK HVVRTIPSGE 300 SAQFEERPIL VFFQGAIYRK DGGIIRQELY YLLKDEKDVH FTFGTVRKNG VNKAGQGMAS 360 SKFCLNIAGD TPSSNRLFDA IVSHCVPVII SDDIELPFED VLDYSEFSVF VRASDAVKEG 420 YLLNLLQSID RDKWTMMWER LKEIAPHFEY QYPSQSGDAV DMIWQAVSRK LSPVQLTIHR 480 RNRYSRFEIQ |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-59 | 112 | 429 | 327 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_565089.1 | 0 | 1 | 489 | 4 | 454 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 489 | 1 | 450 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 83 | 489 | 3 | 411 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002320639.1 | 0 | 112 | 486 | 3 | 374 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002514760.1 | 0 | 1 | 490 | 1 | 490 | catalytic, putative [Ricinus communis] |