| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 30143.m001199 |
| Family | GT47 |
| Protein Properties | Length: 337 Molecular Weight: 38797.4 Isoelectric Point: 8.1267 |
| Chromosome | Chromosome/Scaffold: 30143 Start: 310419 End: 311446 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
 | |||
| Family | Start | End | Evalue |
| GT47 | 46 | 269 | 5.3e-31 |
| FKIYTYTPPQPFSFTSPVESLFFTSLQNSHFITLNPEQAHLFFIPFPSDLSPRSLARVIRDLRTEFPYWNRTLGADHFYISCTGLGYESDRNLVELKKNS VQISCFPSPNGKFVPHKDITLPPLVPSTIHKSSNKRRPYKAFVKYDGVEELRGDLEVLIESQPSDEKTRSEFCLFDYAANISGIGEALSSGCVPLVITER PIQDLPLMDVLRWQEIAVIVGSSD | |||
| Full Sequence |
|---|
| Protein Sequence Length: 337 Download |
| MTMSISHLSL FLVFFSLYTS LSQSSTSLYL SPALFFPNYQ RMLQSFKIYT YTPPQPFSFT 60 SPVESLFFTS LQNSHFITLN PEQAHLFFIP FPSDLSPRSL ARVIRDLRTE FPYWNRTLGA 120 DHFYISCTGL GYESDRNLVE LKKNSVQISC FPSPNGKFVP HKDITLPPLV PSTIHKSSNK 180 RRPYKAFVKY DGVEELRGDL EVLIESQPSD EKTRSEFCLF DYAANISGIG EALSSGCVPL 240 VITERPIQDL PLMDVLRWQE IAVIVGSSDD GFKWVKRVLN GTCSRGDTCE RMRRLGAGAS 300 QHLVWNETPE PYDAFHMVMY QLWLRRHTIR YARREWI |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
 | ||||||||
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 4.0e-20 | 46 | 265 | 275 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
