| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 30147.m014155 |
| Family | GH29 |
| Protein Properties | Length: 484 Molecular Weight: 55191.6 Isoelectric Point: 7.8949 |
| Chromosome | Chromosome/Scaffold: 30147 Start: 659261 End: 661714 |
| Description | alpha-L-fucosidase 1 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GH29 | 42 | 341 | 0 |
| SQLKWQQRELIMFLHFGVNTFTDSEWGTGHENPAIFNPVGLNANQWVSAAAEAGISLMILTAKHHDGFCLWPSKYTDHSVERSPWKNGRGDVVQELVSAA KNYDGIDVGLYLSPWDRHDRRYGHNLQYNEYYLAQLQELLTKYGSVREIWFDGAKGSNAPNMSYYFWDWFAMVKELQSSINIFSDAGPDVRWVGNENGFA GNTCWSTINLTSLSIGNGSTVDYLNTGDPKGTDWLPAECDVSIRKGWFWHKSQTPKKLSKLLEIYYNSVGRNCVLLLNVPPNTTGLISYSDVQRLKEFRT | |||
| Full Sequence |
|---|
| Protein Sequence Length: 484 Download |
| MPKLWHFIFI VTLFLQRSKF GISRREQVPT PPLPVLPLPS FSQLKWQQRE LIMFLHFGVN 60 TFTDSEWGTG HENPAIFNPV GLNANQWVSA AAEAGISLMI LTAKHHDGFC LWPSKYTDHS 120 VERSPWKNGR GDVVQELVSA AKNYDGIDVG LYLSPWDRHD RRYGHNLQYN EYYLAQLQEL 180 LTKYGSVREI WFDGAKGSNA PNMSYYFWDW FAMVKELQSS INIFSDAGPD VRWVGNENGF 240 AGNTCWSTIN LTSLSIGNGS TVDYLNTGDP KGTDWLPAEC DVSIRKGWFW HKSQTPKKLS 300 KLLEIYYNSV GRNCVLLLNV PPNTTGLISY SDVQRLKEFR TAIDTIFATN LAEKCFLKVS 360 SQRGGKDGGF GPENLLDSDH LWTYWVPRNE EKEGGWIEIR CSGGLRFNVI RIQEAIGLGQ 420 RIKRHEIYVD GKKVAKGTTI GYKRLHRLEE VVDGQNVNIK FLESRDVPLI SSIGLHYDPY 480 WNPV |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01120 | Alpha_L_fucos | 3.0e-28 | 77 | 339 | 283 | + Alpha-L-fucosidase. | ||
| smart00812 | Alpha_L_fucos | 2.0e-30 | 46 | 339 | 338 | + Alpha-L-fucosidase. O-Glycosyl hydrolases (EC 3.2.1.-) are a widespread group of enzymes that hydrolyse the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. A classification system for glycosyl hydrolases, based on sequence similarity, has led to the definition of 85 different families. This classification is available on the CAZy (CArbohydrate-Active EnZymes) web site. Because the fold of proteins is better conserved than their sequences, some of the families can be grouped in 'clans'. Family 29 encompasses alpha-L-fucosidases, which is a lysosomal enzyme responsible for hydrolyzing the alpha-1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. Deficiency of alpha-L-fucosidase results in the lysosomal storage disease fucosidosis. | ||
| COG3669 | COG3669 | 4.0e-58 | 43 | 475 | 458 | + Alpha-L-fucosidase [Carbohydrate transport and metabolism] | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004560 | alpha-L-fucosidase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | XP_002270630.1 | 0 | 42 | 483 | 22 | 462 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002270674.1 | 0 | 30 | 483 | 7 | 461 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002318264.1 | 0 | 1 | 483 | 1 | 482 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002322431.1 | 0 | 1 | 483 | 1 | 483 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002510887.1 | 0 | 1 | 484 | 1 | 484 | alpha-l-fucosidase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3eyp_B | 0 | 34 | 476 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3eyp_A | 0 | 34 | 476 | 5 | 454 | A Chain A, Crystal Structure Of Putative Alpha-L-Fucosidase From Bacteroides Thetaiotaomicron |
| PDB | 3ues_B | 0 | 39 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3ues_A | 0 | 39 | 471 | 19 | 471 | A Chain A, Crystal Structure Of Alpha-1,34-Fucosidase From Bifidobacterium Longum Subsp. Infantis Complexed With Deoxyfuconojirimycin |
| PDB | 3mo4_B | 0 | 39 | 471 | 21 | 473 | A Chain A, The Crystal Structure Of An Alpha-(1-3,4)-Fucosidase From Bifidobacterium Longum Subsp. Infantis Atcc 15697 |
