y
Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30147.m014326 |
Family | AA3 |
Protein Properties | Length: 577 Molecular Weight: 63645.2 Isoelectric Point: 9.8656 |
Chromosome | Chromosome/Scaffold: 30147 Start: 458392 End: 461061 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 38 | 572 | 0 |
TSAPRILQYDYIIIGGGTSGCPLAATLSKHAKVLVLERGGSPYGNPNITDIGNFVASLSDTSPYSPSQQFISEDGVYNTRARVLGGGSALNAGFFTRASV DYVKQAGWKEKLVNSSYAWVEKKVAFRPQMLQWQSAVRDGLIEAGLLPDNGFTYDHVHGTKVGGSIFDRDGHRHTAADLLEYADPRNITVYLHATVVKIL FTQRGRPWPRPRAYGVVFEDILGFRHTAFLNRNAKNEIILSAGALGSPQLLMLSGIGPGYHLRAHGIPIVLDQPMVGEGMADNPMNLIFIPSPLPVEVSL IQVAGITRFGSYIESASGLTYAYAWARRFIREYEQSSNQTGEPNMLTPAAMAKAVETVNSLVNATLRGGVILEKVMGPLSTGDLKLRTTNPNDNPSVKFN YFKEPEDLRTCVEGMKTIIDVINSNAFSKFRYRHVPVQALISLMANLPVNLRPRHVTTAISLERFCVDTVMTIWHYHGGCQVGKVVDRDYRVIGVDGIRV IDGSTFLRSPGTNPQATVMMLGRYMGKRILRARLA |
Full Sequence |
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Protein Sequence Length: 577 Download |
MVVPAWKYIG IVLAWTFMLH GISYSEKAPS YTFVNKATSA PRILQYDYII IGGGTSGCPL 60 AATLSKHAKV LVLERGGSPY GNPNITDIGN FVASLSDTSP YSPSQQFISE DGVYNTRARV 120 LGGGSALNAG FFTRASVDYV KQAGWKEKLV NSSYAWVEKK VAFRPQMLQW QSAVRDGLIE 180 AGLLPDNGFT YDHVHGTKVG GSIFDRDGHR HTAADLLEYA DPRNITVYLH ATVVKILFTQ 240 RGRPWPRPRA YGVVFEDILG FRHTAFLNRN AKNEIILSAG ALGSPQLLML SGIGPGYHLR 300 AHGIPIVLDQ PMVGEGMADN PMNLIFIPSP LPVEVSLIQV AGITRFGSYI ESASGLTYAY 360 AWARRFIREY EQSSNQTGEP NMLTPAAMAK AVETVNSLVN ATLRGGVILE KVMGPLSTGD 420 LKLRTTNPND NPSVKFNYFK EPEDLRTCVE GMKTIIDVIN SNAFSKFRYR HVPVQALISL 480 MANLPVNLRP RHVTTAISLE RFCVDTVMTI WHYHGGCQVG KVVDRDYRVI GVDGIRVIDG 540 STFLRSPGTN PQATVMMLGR YMGKRILRAR LADRRSR 600 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK02106 | PRK02106 | 4.0e-32 | 45 | 319 | 324 | + choline dehydrogenase; Validated | ||
TIGR01810 | betA | 4.0e-34 | 47 | 567 | 571 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR03970 | Rv0697 | 3.0e-35 | 47 | 559 | 557 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
COG2303 | BetA | 5.0e-43 | 39 | 572 | 593 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 31 | 571 | 560 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 20 | 577 | 21 | 578 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_200008.1 | 0 | 16 | 570 | 16 | 576 | glucose-methanol-choline (GMC) oxidoreductase family protein [Arabidopsis thaliana] |
RefSeq | XP_002267807.1 | 0 | 6 | 570 | 6 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002267848.1 | 0 | 6 | 570 | 6 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002510860.1 | 0 | 1 | 577 | 1 | 577 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 32 | 572 | 13 | 519 | A Chain A, Crystal Structure Of A 6-Sst6-Sft From Pachysandra Terminalis |
PDB | 3gdp_A | 0 | 32 | 572 | 13 | 519 | A Chain A, Crystal Structure Of A 6-Sst6-Sft From Pachysandra Terminalis |
PDB | 3gdn_B | 0 | 32 | 572 | 13 | 519 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 32 | 572 | 13 | 519 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 32 | 572 | 13 | 519 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |