Basic Information | |
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Species | Ricinus communis |
Cazyme ID | 30190.m011111 |
Family | AA3 |
Protein Properties | Length: 548 Molecular Weight: 59188 Isoelectric Point: 8.0729 |
Chromosome | Chromosome/Scaffold: 30190 Start: 1893519 End: 1897278 |
Description | Glucose-methanol-choline (GMC) oxidoreductase family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA3 | 47 | 541 | 0 |
TSYYDYIIVGGGTAGCPLAATLSQNASVLLLERGGSPYGNPNITNLANFGAALSDPSPTSPSQRFISEDGVINARARVLGGGSCLNAGFYTRASTAYVRT VGWDGRLVNESYQWVEKIVAFEPIMRQWQTAVRDGLLEAGVLPNNGFTYDHFNGTKVGGTIFDQDGHRHSAADLLYYANPSGLTVLLHAPVHKILFRTQG KARPMAHGVVFRDASGAKHRAYLKRGPKNEIIVSAGALGSPQLLMISGVGPAAQLKAHNITVVLDQPMVGQLMSDNPMNAIFIPSPLPVEVSLIQVVGIT HFGSYIEAASGADFDAGVMATRRDYGMFSPKIGQLSTVPPKQRTPEAIAKAIELMNNLDEQAFRGGFILEKIMGPLSTGHLKLTNRNPNDNPSVTFNYFK EPQDLQRCVEGISTIEKVVDSXXLEQFCKDTVMTIWHYHGGCQVGTVVDTNYKVLGVDALRVIDGSTFNASPGTNPQATVMMLGRYMGVKILSER |
Full Sequence |
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Protein Sequence Length: 548 Download |
MGLTLIRFWR LFGACFLGVF FSHSSCSSAD KAPNYSFVKD ATSAPPTSYY DYIIVGGGTA 60 GCPLAATLSQ NASVLLLERG GSPYGNPNIT NLANFGAALS DPSPTSPSQR FISEDGVINA 120 RARVLGGGSC LNAGFYTRAS TAYVRTVGWD GRLVNESYQW VEKIVAFEPI MRQWQTAVRD 180 GLLEAGVLPN NGFTYDHFNG TKVGGTIFDQ DGHRHSAADL LYYANPSGLT VLLHAPVHKI 240 LFRTQGKARP MAHGVVFRDA SGAKHRAYLK RGPKNEIIVS AGALGSPQLL MISGVGPAAQ 300 LKAHNITVVL DQPMVGQLMS DNPMNAIFIP SPLPVEVSLI QVVGITHFGS YIEAASGADF 360 DAGVMATRRD YGMFSPKIGQ LSTVPPKQRT PEAIAKAIEL MNNLDEQAFR GGFILEKIMG 420 PLSTGHLKLT NRNPNDNPSV TFNYFKEPQD LQRCVEGIST IEKVVDSXXL EQFCKDTVMT 480 IWHYHGGCQV GTVVDTNYKV LGVDALRVID GSTFNASPGT NPQATVMMLG RYMGVKILSE 540 RLATEDSK |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam05199 | GMC_oxred_C | 1.0e-23 | 421 | 530 | 136 | + GMC oxidoreductase. This domain found associated with pfam00732. | ||
TIGR01810 | betA | 2.0e-33 | 51 | 530 | 561 | + choline dehydrogenase. Choline dehydrogenase catalyzes the conversion of exogenously supplied choline into the intermediate glycine betaine aldehyde, as part of a two-step oxidative reaction leading to the formation of osmoprotectant betaine. This enzymatic system can be found in both gram-positive and gram-negative bacteria. As in Escherichia coli , Staphylococcus xylosus , and Sinorhizobium meliloti, this enzyme is found associated in a transciptionally co-induced gene cluster with betaine aldehyde dehydrogenase, the second catalytic enzyme in this reaction. Other gram-positive organisms have been shown to employ a different enzymatic system, utlizing a soluable choline oxidase or type III alcohol dehydrogenase instead of choline dehydrogenase. This enzyme is a member of the GMC oxidoreductase family (pfam00732 and pfam05199), sharing a common evoluntionary origin and enzymatic reaction with alcohol dehydrogenase. Outgrouping from this model, Caulobacter crescentus shares sequence homology with choline dehydrogenase, yet other genes participating in this enzymatic reaction have not currently been identified [Cellular processes, Adaptations to atypical conditions]. | ||
TIGR03970 | Rv0697 | 3.0e-35 | 51 | 530 | 541 | + dehydrogenase, Rv0697 family. This model describes a set of dehydrogenases belonging to the glucose-methanol-choline oxidoreductase (GMC oxidoreductase) family. Members of the present family are restricted to Actinobacterial genome contexts containing also members of families TIGR03962 and TIGR03969 (the mycofactocin system), and are proposed to be uniform in function. | ||
COG2303 | BetA | 4.0e-43 | 50 | 543 | 558 | + Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism] | ||
PLN02785 | PLN02785 | 0 | 10 | 542 | 579 | + Protein HOTHEAD |
Gene Ontology | |
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GO Term | Description |
GO:0016614 | oxidoreductase activity, acting on CH-OH group of donors |
GO:0050660 | flavin adenine dinucleotide binding |
GO:0055114 | oxidation-reduction process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI34759.1 | 0 | 23 | 548 | 21 | 578 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_001053612.1 | 0 | 20 | 545 | 19 | 584 | Os04g0573100 [Oryza sativa (japonica cultivar-group)] |
RefSeq | XP_002282510.1 | 0 | 38 | 548 | 1 | 544 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002298074.1 | 0 | 8 | 546 | 5 | 574 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002509694.1 | 0 | 1 | 548 | 1 | 548 | glucose-methanol-choline (gmc) oxidoreductase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3gdp_B | 0 | 36 | 545 | 13 | 521 | A Chain A, Recombinant Horseradish Peroxidase Phe209ser Complex With Benzhydroxamic Acid |
PDB | 3gdp_A | 0 | 36 | 545 | 13 | 521 | A Chain A, Recombinant Horseradish Peroxidase Phe209ser Complex With Benzhydroxamic Acid |
PDB | 3gdn_B | 0 | 36 | 545 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 3gdn_A | 0 | 36 | 545 | 13 | 521 | A Chain A, Almond Hydroxynitrile Lyase In Complex With Benzaldehyde |
PDB | 1ju2_B | 0 | 36 | 545 | 13 | 521 | A Chain A, Crystal Structure Of The Hydroxynitrile Lyase From Almond |