| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 312668 |
| Family | GT20 |
| Protein Properties | Length: 843 Molecular Weight: 95649.1 Isoelectric Point: 7.3298 |
| Chromosome | Chromosome/Scaffold: 1 Start: 7099494 End: 7103611 |
| Description | trehalose-phosphatase/synthase 2 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 10 | 478 | 0 |
| ERPRLLVVANRLPVSAKRTGENSWSLEMSPGGLVSGLLGVTSQLDTKWVGWPGVDVYNEVEKNALTKSLAEMKCIPVFLNGVFDQYYNGYCNGILWPILH HMGLPQEDQHDTNQTFETQYDAYKKANRMFLDVIIQNYEEGDTVWCHDYHLMFLPQYLKEHNNKIKVGWFLHSPFPSSEVYKTLPSRSELLRAVLTADLL GFHTYDFVRHFLSTCTRILGVEGTHEGVVYQGRVTRVAVFPIGIDPDRFIRTCKLPEVTQKMNELKERFAGKKVILGVDRLDMIKGIPQKYLAFEKFLEE NPYWRDKVVLVQIAVPTRNDVPEYRKLKSQVHGLVGRINGRFGSVSSLPIHHLDCSVDFNYLCALYAIADVMLVTSLRDGMNLVSYEFVACQEAKKGVLV LSEFAGAGQSLGVGALLVNPWDVTEVSSAIKDALNMPAEERETRHRFNFQYVYTHSAKKWGSDFMSELN | |||
| Full Sequence |
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| Protein Sequence Length: 843 Download |
| MMHYDDARGE RPRLLVVANR LPVSAKRTGE NSWSLEMSPG GLVSGLLGVT SQLDTKWVGW 60 PGVDVYNEVE KNALTKSLAE MKCIPVFLNG VFDQYYNGYC NGILWPILHH MGLPQEDQHD 120 TNQTFETQYD AYKKANRMFL DVIIQNYEEG DTVWCHDYHL MFLPQYLKEH NNKIKVGWFL 180 HSPFPSSEVY KTLPSRSELL RAVLTADLLG FHTYDFVRHF LSTCTRILGV EGTHEGVVYQ 240 GRVTRVAVFP IGIDPDRFIR TCKLPEVTQK MNELKERFAG KKVILGVDRL DMIKGIPQKY 300 LAFEKFLEEN PYWRDKVVLV QIAVPTRNDV PEYRKLKSQV HGLVGRINGR FGSVSSLPIH 360 HLDCSVDFNY LCALYAIADV MLVTSLRDGM NLVSYEFVAC QEAKKGVLVL SEFAGAGQSL 420 GVGALLVNPW DVTEVSSAIK DALNMPAEER ETRHRFNFQY VYTHSAKKWG SDFMSELNGA 480 IAESEMQIRN IPHGLPQQDV IQRYSQSNNR LIILGFCGTL TEQKNSRSKE MDLKLNPELK 540 GTLKALCNDP KTTVVVLSRS DKDILDKNFG GYNIWLAAEN GMFEKHTNGE WVKSMPQNMN 600 LDWVDSVKNV FKYFTDRTPR SFVKSSETSL VWNYEYADVE FGRAQAGDLL QYLWAGPISN 660 ASVDVVRGNH SVEVHAIGET KGAAIGRILG EIVYRKSMTT PIDFVFCSGY FLEKDEDIYT 720 FFESKILSSK LSHETRSKSS SCNNSRKKKK ISMNVLDLKK ENYFSAAVGQ ARTKARYVID 780 SSLDVVDLLH KLAVADTTMT DSFSDSELYE PRNENENANL KRWINSVRRR KMEIGDTGQI 840 GM* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 0 | 2 | 806 | 805 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03064 | PLN03064 | 0 | 5 | 798 | 847 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 0 | 13 | 709 | 703 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 13 | 478 | 468 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| pfam00982 | Glyco_transf_20 | 0 | 12 | 478 | 473 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50035.1 | 0 | 57 | 800 | 3 | 692 | AC007651_30 Very similar to trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_173142.1 | 0 | 2 | 842 | 1 | 821 | ATTPS2; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_173143.4 | 0 | 2 | 800 | 1 | 776 | ATTPS3; alpha,alpha-trehalose-phosphate synthase (UDP-forming) [Arabidopsis thaliana] |
| Swiss-Prot | Q9FZ57 | 0 | 1 | 842 | 1 | 822 | TPS2_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2; AltName: Full=Trehalose-6-phosphate synthase 2; Short=AtTPS2 |
| Swiss-Prot | Q9SHG0 | 0 | 2 | 800 | 1 | 723 | TPS3_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 3; AltName: Full=Trehalose-6-phosphate synthase 3; Short=AtTPS3 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 13 | 497 | 3 | 472 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 13 | 497 | 3 | 472 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 13 | 497 | 3 | 472 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 13 | 497 | 3 | 472 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 0 | 13 | 497 | 3 | 472 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DW069910 | 288 | 99 | 386 | 0 |
| ES813375 | 361 | 374 | 728 | 0 |
| ES332740 | 306 | 127 | 431 | 0 |
| EL390904 | 268 | 216 | 483 | 0 |
| CB629539 | 271 | 191 | 461 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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