| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 325786 |
| Family | GT48 |
| Protein Properties | Length: 1903 Molecular Weight: 219916 Isoelectric Point: 8.6774 |
| Chromosome | Chromosome/Scaffold: 6 Start: 5194191 End: 5205177 |
| Description | glucan synthase-like 12 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT48 | 1040 | 1748 | 0 |
| VPSNLEARRRISFFSNSLFMDMPMAPKVRNMLSFSVLTPYYTEEVLFSLRDLETPNEDGVSILFYLQKIFPDEWNNFLERVKCLSEEELKESDELEEELR LWASYRGQTLTRTVRGMMYYRKALELQAFLDMAMHEDLMEGYKAVELNSENNSRGERSLWAQCQAVADMKFTYVVSCQQYGIHKRSGDPRAQDILRLMTR YPSLRVAYIDEVEEPVKDKSKKGNQKVYYSVLVKVPKSTDHSSLAQNLDQVIYRIRLPGPAILGEGKPENQNHAIIFSRGEGLQTIDMNQDNYMEEALKM RNLLQEFLTKHDGVRHPSILGLREHIFTGSVSSLAWFMSNQETSFVTIGQRLLANPLRVRFHYGHPDVFDRLFHLTRGGVSKASKVINLSEDIFAGFNST LREGNVTHHEYIQVGKGRDVGLNQISMFEAKIANGNGEQTLSRDIYRLGHRFDFFRMMSCYFTTVGFYFSTLITVLTVYIFLYGRLYLVLSGLEQGLSTQ KGIRDNTPLQIALASQSFVQIGFLMALPMLMEIGLERGFRTALSEFVLMQLQLAPVFFTFSLGTKTHYYGRTLLHGGAKYRSTGRGFVVFHAKFADNYRL YSRSHFVKGLEMMLLLVVYQIFGSAYRGVLAYLLITISMWFMVGTWLFAPFLFNPSGFEWQKIVDDWTDWNKWINNIGGIGVPAEKSWESWWEEEQEHLR YSGKRGLWS | |||
| Full Sequence |
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| Protein Sequence Length: 1903 Download |
| MSATRGGPEQ GPSQPQQRRI VRTQTAGNLG ESFDSEVVPS SLVEIAPILR VANEVESSNP 60 RVAYLCRFYA FEKAHRLDPT SSGRGVRQFK TALLQRLERE HDPTLMGRVK KSDAREMQSF 120 YQHYYKKYIQ ALHNAADKAD RAQLTKAYQT ANVLFEVLKA VNLTQSIEVD REILEAQDKV 180 AEKTQLYVPY NILPLDPDSA NQAIMRYPEI QAAVLALRNT RGLPWPEGHK KKKDEDMLDW 240 LQEMFGFQKD NVANQREHLI LLLANVHIRQ FPKPDQQPKL DDQALTEVMK KLFKNYKKWC 300 KYLGRKSSLW LPTIQQEMQQ RKLLYMALYL LIWGEAANLR FMPECLCYIY HHMAFELYGM 360 LAGNVSPMTG ENVKPAYGGE EDAFLRKVVT PIYEVIQMEA QRSKKGKSKH SQWRNYDDLN 420 EYFWSVDCFR LGWPMRADAD FFCLPVAVPN TEKDGDNSKP TVARDRWVGK VNFVEIRSFW 480 HVFRSFDRMW SFYILCLQAM IIMAWDGGQP SSVFGADVFK KVLSVFITAA IMKLGQAVLD 540 VILNFKAHQS MTLHVKLRYI LKVLSAAAWV IILPVTYAYS WKDPPAFART IKSWFGNAMH 600 SPSLFIIAVV FYLSPNMLAE TNEKHPMCFF ADATIISYIF YTLQPRLYVG RGMHESAFSL 660 FKYTMFWVLL IATKLAFSYY IEIKPLVAPT QAIMKARVTN FQWHEFFPRA KNNIGVVIAL 720 WAPIILVYFM DSQIWYAIFS TLFGGIYGAF RRLGEIRTLG MLRSRFESLP GAFNDRLIPD 780 GKNQQKKKGI RATLSHNFTE DKVPVNKEKE AARFAQLWNT IISSFREEDL ISDREMDLLL 840 VPYWADRDLD LIQWPPFLLA SKIPIALDMA KDSNGKDREL KKRIESDTYM KCAVRECYAS 900 FKNIIKFVVQ GNREKEVIEI IFAEVDKHID TGDLIQEYKM SALPSLYDHF VKLIKYLVNV 960 LLVLDNKEED RDHVVILFQD MLEVVTRDIM MEDYNISRLA TFYRNLGAIR FPIEPVTEAW 1020 KEKIKRIYLL LTTKESAMDV PSNLEARRRI SFFSNSLFMD MPMAPKVRNM LSFSVLTPYY 1080 TEEVLFSLRD LETPNEDGVS ILFYLQKIFP DEWNNFLERV KCLSEEELKE SDELEEELRL 1140 WASYRGQTLT RTVRGMMYYR KALELQAFLD MAMHEDLMEG YKAVELNSEN NSRGERSLWA 1200 QCQAVADMKF TYVVSCQQYG IHKRSGDPRA QDILRLMTRY PSLRVAYIDE VEEPVKDKSK 1260 KGNQKVYYSV LVKVPKSTDH SSLAQNLDQV IYRIRLPGPA ILGEGKPENQ NHAIIFSRGE 1320 GLQTIDMNQD NYMEEALKMR NLLQEFLTKH DGVRHPSILG LREHIFTGSV SSLAWFMSNQ 1380 ETSFVTIGQR LLANPLRVRF HYGHPDVFDR LFHLTRGGVS KASKVINLSE DIFAGFNSTL 1440 REGNVTHHEY IQVGKGRDVG LNQISMFEAK IANGNGEQTL SRDIYRLGHR FDFFRMMSCY 1500 FTTVGFYFST LITVLTVYIF LYGRLYLVLS GLEQGLSTQK GIRDNTPLQI ALASQSFVQI 1560 GFLMALPMLM EIGLERGFRT ALSEFVLMQL QLAPVFFTFS LGTKTHYYGR TLLHGGAKYR 1620 STGRGFVVFH AKFADNYRLY SRSHFVKGLE MMLLLVVYQI FGSAYRGVLA YLLITISMWF 1680 MVGTWLFAPF LFNPSGFEWQ KIVDDWTDWN KWINNIGGIG VPAEKSWESW WEEEQEHLRY 1740 SGKRGLWSIM AGDFLDIVCD EDCFGWKAEI QREFSADVPV DKGANIHDVY RNHCDIDHTG 1800 SHDDTRHNCV YPCLYAHRLG DALACKPVVH RAGFWGSVRT LARGYEIVMG LLLFTPVAFL 1860 AWFPFVSEFQ TRMLFNQAFS RGLQISRILG GHRKDRSSRN KE* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04652 | DUF605 | 9.0e-11 | 45 | 159 | 124 | + Vta1 like. Vta1 (VPS20-associated protein 1) is a positive regulator of Vps4. Vps4 is an ATPase that is required in the multivesicular body (MVB) sorting pathway to dissociate the endosomal sorting complex required for transport (ESCRT). Vta1 promotes correct assembly of Vps4 and stimulates its ATPase activity through its conserved Vta1/SBP1/LIP5 region. | ||
| pfam14288 | FKS1_dom1 | 8.0e-58 | 320 | 436 | 118 | + 1,3-beta-glucan synthase subunit FKS1, domain-1. The FKS1_dom1 domain is likely to be the 'Class I' region just N-terminal to the first set of transmembrane helices that is involved in 1,3-beta-glucan synthesis itself. This family is found on proteins with family Glucan_synthase, pfam02364. | ||
| pfam02364 | Glucan_synthase | 0 | 1040 | 1713 | 720 | + 1,3-beta-glucan synthase component. This family consists of various 1,3-beta-glucan synthase components including Gls1, Gls2 and Gls3 from yeast. 1,3-beta-glucan synthase EC:2.4.1.34 also known as callose synthase catalyzes the formation of a beta-1,3-glucan polymer that is a major component of the fungal cell wall. The reaction catalyzed is:- UDP-glucose + {(1,3)-beta-D-glucosyl}(N) <=> UDP + {(1,3)-beta-D-glucosyl}(N+1). | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000148 | 1,3-beta-D-glucan synthase complex |
| GO:0003843 | 1,3-beta-D-glucan synthase activity |
| GO:0006075 | (1->3)-beta-D-glucan biosynthetic process |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB88264.1 | 0 | 1 | 1902 | 1 | 1963 | callose synthase catalytic subunit-like protein [Arabidopsis thaliana] |
| RefSeq | NP_196804.5 | 0 | 1 | 1746 | 1 | 1807 | ATGSL12 (glucan synthase-like 12); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_196804.5 | 8e-24 | 1822 | 1902 | 1919 | 1999 | ATGSL12 (glucan synthase-like 12); 1,3-beta-glucan synthase/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| Swiss-Prot | Q9LXT9 | 0 | 1 | 1746 | 1 | 1772 | CALS3_ARATH RecName: Full=Callose synthase 3; AltName: Full=1,3-beta-glucan synthase; AltName: Full=Protein GLUCAN SYNTHASE-LIKE 12 |
| Swiss-Prot | Q9LXT9 | 9e-24 | 1822 | 1902 | 1884 | 1964 | CALS3_ARATH RecName: Full=Callose synthase 3; AltName: Full=1,3-beta-glucan synthase; AltName: Full=Protein GLUCAN SYNTHASE-LIKE 12 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2lxm_A | 0.007 | 49 | 158 | 21 | 128 | B Chain B, Lip5-chmp5 |
| PDB | 2lxl_A | 0.01 | 49 | 158 | 21 | 128 | A Chain A, Lip5(mit)2 |
