| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 34442.m000027 |
| Family | GT28 |
| Protein Properties | Length: 362 Molecular Weight: 38490.8 Isoelectric Point: 9.664 |
| Chromosome | Chromosome/Scaffold: 34442 Start: 250 End: 1338 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT28 | 187 | 349 | 0 |
| ILVTGGSQGARLLSELVPEAIAKLPEEMRGRMKVFQQARAESMEHARKIYRNAMVDCEVAPFFRDMAGRLRQSHIVVGRAGSSTCCELAVAGRPSILVPL KIAADDHQRFNAKLLEEAGGAAVCLEDELTVDALAGALNALLKSPDRLARMAKGARSVAVPDA | |||
| Full Sequence |
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| Protein Sequence Length: 362 Download |
| MSGKLAIVAA GGTGGHMFPA QALSEALISR GWRVVLATDE RGAFYADKFP AQERLALSAA 60 TAKAGDPIGM IKAGIAVTQG VLQAKQAFAR LNPSVVVGFG GYPALPALLA ALLEKRPTVI 120 HEQNAVLGRV NRFLAPYVTE VACAFPTLQM AKPSVKARAH VVGSPVRPEI RDLADVAYLP 180 PEVQFRILVT GGSQGARLLS ELVPEAIAKL PEEMRGRMKV FQQARAESME HARKIYRNAM 240 VDCEVAPFFR DMAGRLRQSH IVVGRAGSST CCELAVAGRP SILVPLKIAA DDHQRFNAKL 300 LEEAGGAAVC LEDELTVDAL AGALNALLKS PDRLARMAKG ARSVAVPDAA EHLADLVERT 360 AR 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam04101 | Glyco_tran_28_C | 1.0e-35 | 186 | 353 | 168 | + Glycosyltransferase family 28 C-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site. | ||
| TIGR01133 | murG | 1.0e-80 | 4 | 357 | 370 | + undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase. RM 8449890 RT The final step of peptidoglycan subunit assembly in Escherichia coli occurs in the cytoplasm. RA Bupp K, van Heijenoort J. RL J Bacteriol 1993 Mar;175(6):1841-3 [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]. | ||
| COG0707 | MurG | 1.0e-102 | 4 | 362 | 363 | + UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase [Cell envelope biogenesis, outer membrane] | ||
| cd03785 | GT1_MurG | 5.0e-122 | 7 | 356 | 353 | + MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| PRK00726 | murG | 8.0e-126 | 4 | 362 | 363 | + undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005975 | carbohydrate metabolic process |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0030246 | carbohydrate binding |
| GO:0030259 | lipid glycosylation |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF06830.1 | 0 | 4 | 312 | 3 | 311 | AF099188_2 MurG [Caulobacter crescentus CB15] |
| RefSeq | NP_421354.1 | 0 | 4 | 362 | 3 | 361 | N-acetylglucosaminyl transferase [Caulobacter crescentus CB15] |
| RefSeq | XP_002536704.1 | 0 | 1 | 362 | 1 | 362 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase, putative [Ricinus communis] |
| RefSeq | YP_001685291.1 | 0 | 4 | 362 | 3 | 361 | N-acetylglucosaminyl transferase [Caulobacter sp. K31] |
| RefSeq | ZP_06122444.1 | 0 | 4 | 362 | 3 | 361 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [Caulobacter segnis ATCC 21756] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3s2u_A | 0 | 1 | 362 | 1 | 356 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_B | 0 | 3 | 362 | 6 | 355 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1nlm_A | 0 | 3 | 362 | 6 | 355 | A Chain A, Crystal Structure Of The Pseudomonas Aeruginosa Murg:udp-glcnac Substrate Comp |
| PDB | 1f0k_B | 0 | 3 | 362 | 6 | 355 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| PDB | 1f0k_A | 0 | 3 | 362 | 6 | 355 | A Chain A, The 1.9 Angstrom Crystal Structure Of E. Coli Murg |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| CN815584 | 182 | 181 | 362 | 4e-29 |
| CO115843 | 277 | 88 | 350 | 5e-25 |
| ES821435 | 333 | 9 | 323 | 1e-23 |
| DT604869 | 178 | 186 | 362 | 8e-23 |
| CO093991 | 247 | 118 | 350 | 3e-21 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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