Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 344960 |
Family | GT47 |
Protein Properties | Length: 459 Molecular Weight: 52815.9 Isoelectric Point: 9.9875 |
Chromosome | Chromosome/Scaffold: 4 Start: 15110479 End: 15113381 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 52 | 398 | 0 |
GRYIYIHNLPSRFNLEIIKDCKSITRPKDKISMCKYLENSGIGPLIGGDGFDYSPSWYATNQFMLEVIFHEKMKRYECLTRNSSLASAIYVPYYAGLDFR RHLRRRNVAARDAAGKELVKWLKKQPQWKDMSGRDHFLVTGRISRDFRRNSDNKSAWGTNFMLLPESLNLTFLTIERSLTSHNEFAIPYPTYFHPTSTSE ILRWQDKIRLTNRTILFSFAGAQRPIRNQNGLVRTQVIKQCKSSSNTCRFLDCDVKANISCDDPISLMKLFESSVFCLQPPGDSLTRRSVFDSILAGCIP VFFNQGSAYKQYRWHIPKNNSEYSVYIPVKELRTGGKNKIEEILRGI |
Full Sequence |
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Protein Sequence Length: 459 Download |
MEEKTTTLLL FLSLLTISLL LLRLSQDKII LITTTTTTSD SDHQRRHDPC LGRYIYIHNL 60 PSRFNLEIIK DCKSITRPKD KISMCKYLEN SGIGPLIGGD GFDYSPSWYA TNQFMLEVIF 120 HEKMKRYECL TRNSSLASAI YVPYYAGLDF RRHLRRRNVA ARDAAGKELV KWLKKQPQWK 180 DMSGRDHFLV TGRISRDFRR NSDNKSAWGT NFMLLPESLN LTFLTIERSL TSHNEFAIPY 240 PTYFHPTSTS EILRWQDKIR LTNRTILFSF AGAQRPIRNQ NGLVRTQVIK QCKSSSNTCR 300 FLDCDVKANI SCDDPISLMK LFESSVFCLQ PPGDSLTRRS VFDSILAGCI PVFFNQGSAY 360 KQYRWHIPKN NSEYSVYIPV KELRTGGKNK IEEILRGIPN ERVVGMRENV IRLIPKIVYS 420 KPNRNKPDGE ILEDAFDVAV KGVVKGIEGI RRKEFKTE* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 9.0e-64 | 49 | 398 | 361 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD15405.1 | 0 | 26 | 458 | 49 | 487 | hypothetical protein [Arabidopsis thaliana] |
RefSeq | NP_180759.2 | 0 | 26 | 458 | 41 | 479 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002300146.1 | 0 | 48 | 452 | 106 | 490 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002518609.1 | 0 | 37 | 453 | 63 | 469 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |
RefSeq | XP_002532518.1 | 0 | 48 | 452 | 100 | 499 | Xyloglucan galactosyltransferase KATAMARI1, putative [Ricinus communis] |