| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 472383 |
| Family | GT47 |
| Protein Properties | Length: 463 Molecular Weight: 52829.5 Isoelectric Point: 9.5464 |
| Chromosome | Chromosome/Scaffold: 1 Start: 9257627 End: 9260201 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT47 | 87 | 376 | 0 |
| LSLKIYVYDENEIDGLKELLYGRDGSVKTTACLKGQWGSQVKIHKLLLESKFRTIKKDEADLFFVPAYVKCVRMLGGLNDKEINQTYVKVLSQMPYFRRS GGRDHIFVFPSGAGAHLFRSWSTFINRSIILTPEADRTDKKDTTAFNTWKDIIIPGNVDDAMTKNGQPDVQPLPLSKRKYLANYLGRAQGKAGRLKLIDL SKQYPDKLECPDLKFSGTEKFGRTTYFEHLRNAKFCLAPRGESSWTLRFYESFFVECVPVLLSDHAELPFQNVIDYAQVSIKWPSTRIGA | |||
| Full Sequence |
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| Protein Sequence Length: 463 Download |
| MASLTSNKPR NFGAYSHYAT PCTRTHQIGA LFLVVSTFFV TRLFDQWFSE SNSVSPVIDL 60 RRTSSSYGIT TYNGILRWPE RGYGSHLSLK IYVYDENEID GLKELLYGRD GSVKTTACLK 120 GQWGSQVKIH KLLLESKFRT IKKDEADLFF VPAYVKCVRM LGGLNDKEIN QTYVKVLSQM 180 PYFRRSGGRD HIFVFPSGAG AHLFRSWSTF INRSIILTPE ADRTDKKDTT AFNTWKDIII 240 PGNVDDAMTK NGQPDVQPLP LSKRKYLANY LGRAQGKAGR LKLIDLSKQY PDKLECPDLK 300 FSGTEKFGRT TYFEHLRNAK FCLAPRGESS WTLRFYESFF VECVPVLLSD HAELPFQNVI 360 DYAQVSIKWP STRIGAEFLD YLASISDKDI EGMIARGREI RCLFVYGPDS APCSAVKGIL 420 WELQRKVRHF QQSTETFWLH NGSFVNRELV QFSSWRPPMP LP* |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-43 | 89 | 375 | 299 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAF87908.1 | 0 | 1 | 462 | 1 | 414 | AC015447_18 Hypothetical protein [Arabidopsis thaliana] |
| GenBank | AAL75891.1 | 0 | 1 | 462 | 1 | 462 | At1g21480/F24J8_23 [Arabidopsis thaliana] |
| GenBank | AAM61682.1 | 0 | 1 | 462 | 1 | 462 | unknown [Arabidopsis thaliana] |
| RefSeq | NP_564141.1 | 0 | 1 | 462 | 1 | 462 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_973879.1 | 0 | 1 | 386 | 1 | 386 | exostosin family protein [Arabidopsis thaliana] |
| Hydropathy |
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| EST Download unfiltered results here | ||||
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| Hit | Length | Start | End | EValue |
| BX841155 | 335 | 1 | 335 | 0 |
| CX668832 | 291 | 149 | 439 | 0 |
| EX093096 | 288 | 1 | 287 | 0 |
| CD825121 | 244 | 157 | 400 | 0 |
| FE707914 | 279 | 129 | 407 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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| Phylogeny |
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