| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 472779 |
| Family | AA7 |
| Protein Properties | Length: 553 Molecular Weight: 61657.3 Isoelectric Point: 9.7376 |
| Chromosome | Chromosome/Scaffold: 1 Start: 11329977 End: 11331737 |
| Description | FAD-binding Berberine family protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 102 | 546 | 0 |
| LAIIAAKHVSHVQATVVCAKSNGIQIRIRSGGHDNEGFSYVSSVPFVILDMHNLRSIDVNVTSKNAWIQAGATLGELYVKINEASQTLAFPAGVCPTVGA GGHISGGGFGNLMRKFGITVDHVIDAQLIDVKGKLLNRAAMGEDLFWAIRGGGSSFGVILSWKINLVEVPKILTVFKVNKTLEQGGTDVLYKWQLVANKL PDSLFITAWPRTVNGPKPGERTIAVVFYAQFLGPTDKLMEIMDQSFPELELSREDCHEMSWINTTLFWANYPTGTPKSVLLDRPPTNSVSFKSKSDFVKK PIPKKGLEKLWKTMFKFNSSVSLQFNPYGGVMDRIPATATAFPHRKGNLFKVQYSTMWFDANATESSLAMMKELFEVAEPYVSSNPREAFFNFRDVDIGS NPSGETNVDEAKIYGYKYFLGNLKRLMDVKAKYDPENFFKNEQSI | |||
| Full Sequence |
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| Protein Sequence Length: 553 Download |
| MKEALVFLLF LTKKFPEKFN SCSKKKETLY VLCLVLLISI LEAPVTKPNF GKFIECLRDR 60 TTPENPITDA ISIADNTTTF LSSYVSYTKN KRFSSPNFKK LLAIIAAKHV SHVQATVVCA 120 KSNGIQIRIR SGGHDNEGFS YVSSVPFVIL DMHNLRSIDV NVTSKNAWIQ AGATLGELYV 180 KINEASQTLA FPAGVCPTVG AGGHISGGGF GNLMRKFGIT VDHVIDAQLI DVKGKLLNRA 240 AMGEDLFWAI RGGGSSFGVI LSWKINLVEV PKILTVFKVN KTLEQGGTDV LYKWQLVANK 300 LPDSLFITAW PRTVNGPKPG ERTIAVVFYA QFLGPTDKLM EIMDQSFPEL ELSREDCHEM 360 SWINTTLFWA NYPTGTPKSV LLDRPPTNSV SFKSKSDFVK KPIPKKGLEK LWKTMFKFNS 420 SVSLQFNPYG GVMDRIPATA TAFPHRKGNL FKVQYSTMWF DANATESSLA MMKELFEVAE 480 PYVSSNPREA FFNFRDVDIG SNPSGETNVD EAKIYGYKYF LGNLKRLMDV KAKYDPENFF 540 KNEQSIPPVR VK* 600 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 3.0e-12 | 102 | 549 | 475 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 2.0e-14 | 490 | 547 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam01565 | FAD_binding_4 | 1.0e-18 | 102 | 238 | 138 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0016491 | oxidoreductase activity |
| GO:0050660 | flavin adenine dinucleotide binding |
| GO:0055114 | oxidation-reduction process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAM13232.1 | 0 | 1 | 552 | 1 | 552 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_173965.1 | 0 | 1 | 552 | 1 | 552 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_173966.1 | 0 | 26 | 551 | 2 | 527 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564244.1 | 0 | 26 | 549 | 2 | 525 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564245.1 | 0 | 42 | 551 | 18 | 529 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 53 | 549 | 7 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_B | 0 | 53 | 549 | 11 | 496 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_A | 0 | 53 | 549 | 11 | 496 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsh_A | 0 | 53 | 549 | 11 | 496 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
| PDB | 4dns_B | 0 | 53 | 549 | 13 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG481331 | 278 | 69 | 345 | 0 |
| EG481329 | 269 | 42 | 309 | 0 |
| ES905941 | 285 | 47 | 330 | 0 |
| EG481242 | 276 | 51 | 325 | 0 |
| FY454239 | 289 | 215 | 502 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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