| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 474368 |
| Family | GT4 |
| Protein Properties | Length: 671 Molecular Weight: 75248 Isoelectric Point: 10.6387 |
| Chromosome | Chromosome/Scaffold: 1 Start: 27950999 End: 27954580 |
| Description | UDP-Glycosyltransferase superfamily protein |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| GT4 | 495 | 636 | 3.9e-21 |
| MKSVSLTLDNAVRSEKQELKVLLGSVGSKSNKVGYVKEMLSFLSKNGNLSKSVMWTPATTRVASLYSAADVYVTNSQGVGETFGRVTIEAMAYGLAVVGT DAGGTKEMVQHNVTGLLHSMGRSGNKELAHNLLYLLRNADAR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 671 Download |
| MEEIRLSPLR QTSVKSSLSG RSTPRGTPRL HSGRTPRRGH VGGGAFQLFR SSRLVYWLLL 60 ITLWTYLGFY VQSRWAHDNE SKVEFLRFGG RPRTDVLYVE KIKGMDAVAN ENSEALVNIT 120 GKDDAGLSKR TDVSLIKKDD GASRRSLSSK QKTRKTVRSS RSKVRGKQKV IKEVLETKDL 180 DAEQDPQLPL TNATYGKLLG PFGSLEDKVL EWSPHRRSGT CDRKSDFKRL VWSRRFVLLF 240 HELSMTGAPI SMMELASELL SCGATVSAVV LSRRGGLMQE LTRRRIKVVE DKGELSFKTS 300 MKADLVIAGS AVCTSWIDQY MNHHPAGGSQ IAWWIMENRR EYFDRAKPVL DHVKMLIFLS 360 ESQSRQWLTW CEEEHIKLRS QPVIVPLSVN DELAFVAGIP SSLNTPTLSP EKMREKRQIL 420 RESVRMELGL TDADMLVMSL SSINPTKGQL LLLESIALAL SERGKESQRN HKGIIRKEKV 480 SLSSKHRLRG SSRQMKSVSL TLDNAVRSEK QELKVLLGSV GSKSNKVGYV KEMLSFLSKN 540 GNLSKSVMWT PATTRVASLY SAADVYVTNS QGVGETFGRV TIEAMAYGLA VVGTDAGGTK 600 EMVQHNVTGL LHSMGRSGNK ELAHNLLYLL RNADARLRLG SEGRKMVEKM YMKQHMYKRF 660 VDVLVKCMRP * |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd03825 | GT1_wcfI_like | 1.0e-17 | 554 | 651 | 98 | + This family is most closely related to the GT1 family of glycosyltransferases. wcfI in Bacteroides fragilis has been shown to be involved in the capsular polysaccharide biosynthesis. | ||
| pfam00534 | Glycos_transf_1 | 8.0e-18 | 477 | 646 | 172 | + Glycosyl transferases group 1. Mutations in this domain of human PIGA lead to disease (Paroxysmal Nocturnal haemoglobinuria). Members of this family transfer activated sugars to a variety of substrates, including glycogen, Fructose-6-phosphate and lipopolysaccharides. Members of this family transfer UDP, ADP, GDP or CMP linked sugars. The eukaryotic glycogen synthases may be distant members of this family. | ||
| COG0438 | RfaG | 7.0e-18 | 496 | 670 | 177 | + Glycosyltransferase [Cell envelope biogenesis, outer membrane] | ||
| cd03808 | GT1_cap1E_like | 4.0e-22 | 542 | 662 | 121 | + This family is most closely related to the GT1 family of glycosyltransferases. cap1E in Streptococcus pneumoniae is required for the synthesis of type 1 capsular polysaccharides. | ||
| cd03801 | GT1_YqgM_like | 2.0e-24 | 505 | 664 | 162 | + This family is most closely related to the GT1 family of glycosyltransferases and named after YqgM in Bacillus licheniformis about which little is known. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0009058 | biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_175651.1 | 0 | 1 | 670 | 1 | 670 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | NP_188215.1 | 0 | 1 | 670 | 1 | 697 | glycosyl transferase family 1 protein [Arabidopsis thaliana] |
| RefSeq | XP_002284822.1 | 0 | 1 | 669 | 1 | 689 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002298139.1 | 0 | 4 | 669 | 15 | 679 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002528176.1 | 0 | 4 | 669 | 15 | 684 | glycosyltransferase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2jjm_L | 0.00000006 | 537 | 669 | 259 | 387 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_K | 0.00000006 | 537 | 669 | 259 | 387 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_J | 0.00000006 | 537 | 669 | 259 | 387 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_I | 0.00000006 | 537 | 669 | 259 | 387 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
| PDB | 2jjm_H | 0.00000006 | 537 | 669 | 259 | 387 | A Chain A, Crystal Structure Of A Family Gt4 Glycosyltransferase From Bacillus Anthracis Orf Ba1558. |
