Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 476604 |
Family | GT47 |
Protein Properties | Length: 459 Molecular Weight: 52438.8 Isoelectric Point: 9.6205 |
Chromosome | Chromosome/Scaffold: 2 Start: 16386972 End: 16388771 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 71 | 391 | 0 |
VLKVFMYNLPSEFHFGILNWHKTGSEIWPNVNNISTIPSYPGGLNRQHSVEYWLTLDLLASETPEIKRPCSSAAIRVKNSNEADIVFVPFFASLSYNRKS KLRGNETISGDRLLQERLVEFLKSQDEWKRFDGKDHLIIAHHPNSLLYAKNFLGSAMFVLSDFGRYSSANANLEKDIIAPYLHVVKTISNNESAPFEKRP VLAYFQGAIYRKDGGTIRQELYNLLRDEKDVHFAFGTVRRNGTKQTGKGMASSKFCLNIAGDTPSSNRLFDAIVSHCVPVIISDQIELPFEDSLDYSGFS VFVHASEAVKKGFLVNLLRGI |
Full Sequence |
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Protein Sequence Length: 459 Download |
MSEKSLLSSK FLFYTITVSM LLFIVSSLFF LQRNESSFTS SLVRKLILPR TDIKNDEFGK 60 IDTLCDRNRD VLKVFMYNLP SEFHFGILNW HKTGSEIWPN VNNISTIPSY PGGLNRQHSV 120 EYWLTLDLLA SETPEIKRPC SSAAIRVKNS NEADIVFVPF FASLSYNRKS KLRGNETISG 180 DRLLQERLVE FLKSQDEWKR FDGKDHLIIA HHPNSLLYAK NFLGSAMFVL SDFGRYSSAN 240 ANLEKDIIAP YLHVVKTISN NESAPFEKRP VLAYFQGAIY RKDGGTIRQE LYNLLRDEKD 300 VHFAFGTVRR NGTKQTGKGM ASSKFCLNIA GDTPSSNRLF DAIVSHCVPV IISDQIELPF 360 EDSLDYSGFS VFVHASEAVK KGFLVNLLRG ITEDQWKKKW GRLKEVAGCF EYRFPSHPGD 420 SVNMIWSAVS HKLSSLQFDV HRKNRYRRSE MFDRNRSS* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-58 | 72 | 391 | 329 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD55303.1 | 0 | 1 | 458 | 1 | 458 | AC008263_34 F25A4.34 [Arabidopsis thaliana] |
RefSeq | NP_565089.1 | 0 | 1 | 458 | 4 | 461 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002284930.1 | 0 | 1 | 452 | 1 | 451 | PREDICTED: hypothetical protein isoform 1 [Vitis vinifera] |
RefSeq | XP_002284932.1 | 0 | 65 | 452 | 27 | 412 | PREDICTED: hypothetical protein isoform 2 [Vitis vinifera] |
RefSeq | XP_002514760.1 | 0 | 61 | 451 | 101 | 489 | catalytic, putative [Ricinus communis] |