Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 477022 |
Family | GT20 |
Protein Properties | Length: 956 Molecular Weight: 107401 Isoelectric Point: 7.3539 |
Chromosome | Chromosome/Scaffold: 2 Start: 18270212 End: 18275608 |
Description | trehalose-6-phosphate synthase |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT20 | 89 | 570 | 0 |
YNRQRLLVVANRLPVSAVRRGEDSWSLEISAGGLVSALLGVKEFEARWIGWAGVNVPDEVGQKALSKALAEKRCIPVFLDEEIVHQYYNGYCNNILWPLF HYLGLPQEDRLATTRSFQSQFAAYKKANQMFADVVNEHYEEGDVVWCHDYHLMFLPKCLKEYNSKMKVGWFLHTPFPSSEIHRTLPSRSELLRSVLAADL VGFHTYDYARHFVSACTRILGLEGTPEGVEDQGRLTRVAAFPIGIDSERFIRALEVPDVIQHMKELKERFAGRKVMLGVDRLDMIKGIPQKILAFEKFLE ENASWRDKVVLLQIAVPTRTDVPEFSFTHGNITKHLLKKLTSQVHEIVGRINGRFGTLTAVPIHHLDRSLDFYALCALYAVTDVALVTSLRDGMNLVSYE FVACQEAKKGVLILSEFAGAAQSLGAGAILVNPWNITEVAASIGQALNMTAEEREKRHRHNFHHVKTHTAQEWAETFVSELN |
Full Sequence |
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Protein Sequence Length: 956 Download |
MPGNKYNCSS SHIPLSRTER LLRDRELREK RKSNRARNPN DIAGSSDNSE NDLRLEGDSS 60 RQYVEQYLEG AAAAMAHDDA CERQEARPYN RQRLLVVANR LPVSAVRRGE DSWSLEISAG 120 GLVSALLGVK EFEARWIGWA GVNVPDEVGQ KALSKALAEK RCIPVFLDEE IVHQYYNGYC 180 NNILWPLFHY LGLPQEDRLA TTRSFQSQFA AYKKANQMFA DVVNEHYEEG DVVWCHDYHL 240 MFLPKCLKEY NSKMKVGWFL HTPFPSSEIH RTLPSRSELL RSVLAADLVG FHTYDYARHF 300 VSACTRILGL EGTPEGVEDQ GRLTRVAAFP IGIDSERFIR ALEVPDVIQH MKELKERFAG 360 RKVMLGVDRL DMIKGIPQKI LAFEKFLEEN ASWRDKVVLL QIAVPTRTDV PEFSFTHGNI 420 TKHLLKKLTS QVHEIVGRIN GRFGTLTAVP IHHLDRSLDF YALCALYAVT DVALVTSLRD 480 GMNLVSYEFV ACQEAKKGVL ILSEFAGAAQ SLGAGAILVN PWNITEVAAS IGQALNMTAE 540 EREKRHRHNF HHVKTHTAQE WAETFVSELN DTVIEAQLRI SKVPPELPQH DAIQRYSKSN 600 NRLLILGFNA TLTEPVDNQG RRGDQIKEMD LNLHPELKGP LKALCSDPST TIVVLSGSSR 660 SVLDKNFGEY DMWLAAENGM FLRLTNGEWM TTMPEHLNME WVDSVKHVFK YFTERTPRSH 720 FETRDTSLIW NYKYADIEFG RIQARDLLQH LWTGPISNAS VDVVQGSRSV EVRAVGVTKG 780 AAIDRILGEI VHSKLMTTPI DYVLCIGHFL GKDEDVYTFF EPELPSDIPA IARARPSSDS 840 GTKSSSGDRR PPSKLTHNNN KSGSKSSSSS NSNNNNKSSQ RSLQSERKSG SNHSLGTSRR 900 PSPEKISWNV LDLKGENYFS CAVGRTRTNA RYLLGSPDDV VCFLEKLADT TTSAP* 960 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PLN03063 | PLN03063 | 5.0e-13 | 894 | 953 | 62 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03064 | PLN03064 | 0 | 1 | 955 | 959 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
PLN03063 | PLN03063 | 0 | 91 | 826 | 736 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
TIGR02400 | trehalose_OtsA | 0 | 93 | 571 | 481 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., PMID:12890033) [Cellular processes, Adaptations to atypical conditions]. | ||
pfam00982 | Glyco_transf_20 | 0 | 92 | 571 | 486 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0005992 | trehalose biosynthetic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAA69879.1 | 0 | 1 | 953 | 1 | 941 | trehalose-6-phosphate synthase [Arabidopsis thaliana] |
RefSeq | NP_177979.1 | 0 | 1 | 953 | 1 | 941 | ATTPS1 (TREHALOSE-6-PHOSPHATE SYNTHASE); alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002285632.1 | 0 | 1 | 953 | 1 | 926 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002331300.1 | 0 | 1 | 952 | 1 | 922 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531237.1 | 0 | 1 | 948 | 1 | 920 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 1gz5_D | 0 | 93 | 573 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_C | 0 | 93 | 573 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_B | 0 | 93 | 573 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 1gz5_A | 0 | 93 | 573 | 2 | 454 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
PDB | 2wtx_D | 0 | 93 | 573 | 3 | 455 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
ES813375 | 361 | 466 | 826 | 0 |
CX546763 | 302 | 81 | 382 | 0 |
CV711307 | 294 | 90 | 383 | 0 |
DW069910 | 300 | 179 | 478 | 0 |
FY436130 | 265 | 573 | 836 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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