Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 481698 |
Family | GT47 |
Protein Properties | Length: 453 Molecular Weight: 52178.7 Isoelectric Point: 9.6167 |
Chromosome | Chromosome/Scaffold: 4 Start: 12045267 End: 12047278 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 97 | 397 | 0 |
NLKIYVYDLPSKFNKDWLANDRCSNHLFAAEVALHKAFLSLEGDIRTEDPYEADFFFVPVYVSCNFSTINGFPAIGHARTLINDAIKFVSTQYPFWNRNN GSDHVFTATHDFGSCFHTMEDRAIADGVPKILRSSIVLQTFGVTFNHPCQEVENVVIPPYISPESLHKTLKNIPVNKERDIWAFFRGKMELHPKNISGRF YSKRVRTKIWRSYGGDRRFYLQRQRFSGYQLEIARSVFCLCPLGWAPWSPRLVESVALGCVPVIIADGIRLPFPSAVRWPDISLTVAERDVGKLGDILEH V |
Full Sequence |
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Protein Sequence Length: 453 Download |
MITQKQRRTE KSLCLKHYYK WFLCFFLTLY FLASFFVDHD QDHDHDQRSS SSRSNPLLTN 60 SKPKLFASRA MFESKIHDHK LGFAPQRPNI RTDVFNNLKI YVYDLPSKFN KDWLANDRCS 120 NHLFAAEVAL HKAFLSLEGD IRTEDPYEAD FFFVPVYVSC NFSTINGFPA IGHARTLIND 180 AIKFVSTQYP FWNRNNGSDH VFTATHDFGS CFHTMEDRAI ADGVPKILRS SIVLQTFGVT 240 FNHPCQEVEN VVIPPYISPE SLHKTLKNIP VNKERDIWAF FRGKMELHPK NISGRFYSKR 300 VRTKIWRSYG GDRRFYLQRQ RFSGYQLEIA RSVFCLCPLG WAPWSPRLVE SVALGCVPVI 360 IADGIRLPFP SAVRWPDISL TVAERDVGKL GDILEHVVAT NLSVIQRNLE DPSVRRALMF 420 NVPSREGDAT WQVLEALSKK LNRSVRRSNS FL* |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 6.0e-68 | 98 | 394 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAX33322.1 | 0 | 5 | 446 | 11 | 435 | secondary cell wall-related glycosyltransferase family 47 [Populus tremula x Populus tremuloides] |
GenBank | ABI64067.1 | 0 | 5 | 446 | 11 | 435 | glycosyltransferase GT47C [Populus tremula x Populus alba] |
RefSeq | NP_850113.2 | 0 | 1 | 452 | 1 | 448 | FRA8 (FRAGILE FIBER 8); glucuronosyltransferase/ transferase [Arabidopsis thaliana] |
RefSeq | XP_002314302.1 | 0 | 5 | 446 | 31 | 455 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523710.1 | 0 | 4 | 446 | 28 | 454 | transferase, putative [Ricinus communis] |