| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 485074 |
| Family | GT35 |
| Protein Properties | Length: 842 Molecular Weight: 95224.4 Isoelectric Point: 6.3124 |
| Chromosome | Chromosome/Scaffold: 5 Start: 12996865 End: 13001980 |
| Description | alpha-glucan phosphorylase 2 |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT35 | 114 | 836 | 0 |
| ALRKLGYELEEIAEQEKDAALGNGGLGRLASCFLDSMATLNLPAWGYGLRYRHGLFKQIITKKGQEEIPEDWLEKFSPWEIVRHDVVFPVRFFGKVQINP DGSRKWVGGDVVQALAYDVPIPGYNTKNTISLRLWEAKARAEDLDLFQFNEGEYELAAQLHSRAQQICTVLYPGDATENGKLLRLKQQFFLCSASLQDII SRFHERSTAEGSRKWSDFPSKVAVQMNDTHPTLAIPELMRLLMDDNGLGWDEAWDVTSRTVAYTNHTVLPEALEKWSQSLMWKLLPRHMEIIEEIDKRFV QTIRDTRVDLEDKISSLSILDNNPQKPVVRMANLCVVSSHTVNGVAQLHSDILKAELFADYVSIWPNKFQNKTNGITPRRWLRFCSPELSDIITKWLKTD KWITDLDLLTGLRQFADNEELQSEWASAKTANKKRLAQYIERVTGVSIDPTSLFDIQVKRIHEYKRQLMNILGVIYRFKKLKEMKPEERKKTVPRTVMIG GKAFATYTNAKRIVKLVNDVGDVVNSDPEVNEYLKVVFVPNYNVTVAEMLIPGSELSQHISTAGMEASGTSNMKFALNGCLIIGTLDGANVEIREEVGEE NFFLFGATADQVPRLRKEREDGLFKPDPRFEEAKQFVKSGVFGSYDYGPLLDSLEGNTGFGRGDYFLVGYDFPSYMDAQAKVDEAYKDRKGWLKMSILST AGSGKFSSDRTIAQYAKEIWNIE | |||
| Full Sequence |
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| Protein Sequence Length: 842 Download |
| MANANGKAAT SLPEKISAKA NPEANEATEI AGNIIYHAKY SPHFSPLKFG PEQALYATAE 60 SLRDRLIQLW NETYVHFNKV DPKQTYYLSM EYLQGRALTN AIGNLNLQGP YADALRKLGY 120 ELEEIAEQEK DAALGNGGLG RLASCFLDSM ATLNLPAWGY GLRYRHGLFK QIITKKGQEE 180 IPEDWLEKFS PWEIVRHDVV FPVRFFGKVQ INPDGSRKWV GGDVVQALAY DVPIPGYNTK 240 NTISLRLWEA KARAEDLDLF QFNEGEYELA AQLHSRAQQI CTVLYPGDAT ENGKLLRLKQ 300 QFFLCSASLQ DIISRFHERS TAEGSRKWSD FPSKVAVQMN DTHPTLAIPE LMRLLMDDNG 360 LGWDEAWDVT SRTVAYTNHT VLPEALEKWS QSLMWKLLPR HMEIIEEIDK RFVQTIRDTR 420 VDLEDKISSL SILDNNPQKP VVRMANLCVV SSHTVNGVAQ LHSDILKAEL FADYVSIWPN 480 KFQNKTNGIT PRRWLRFCSP ELSDIITKWL KTDKWITDLD LLTGLRQFAD NEELQSEWAS 540 AKTANKKRLA QYIERVTGVS IDPTSLFDIQ VKRIHEYKRQ LMNILGVIYR FKKLKEMKPE 600 ERKKTVPRTV MIGGKAFATY TNAKRIVKLV NDVGDVVNSD PEVNEYLKVV FVPNYNVTVA 660 EMLIPGSELS QHISTAGMEA SGTSNMKFAL NGCLIIGTLD GANVEIREEV GEENFFLFGA 720 TADQVPRLRK EREDGLFKPD PRFEEAKQFV KSGVFGSYDY GPLLDSLEGN TGFGRGDYFL 780 VGYDFPSYMD AQAKVDEAYK DRKGWLKMSI LSTAGSGKFS SDRTIAQYAK EIWNIEACPV 840 P* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd04300 | GT1_Glycogen_Phosphorylase | 0 | 33 | 835 | 811 | + This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. | ||
| TIGR02093 | P_ylase | 0 | 34 | 835 | 810 | + glycogen/starch/alpha-glucan phosphorylases. This family consists of phosphorylases. Members use phosphate to break alpha 1,4 linkages between pairs of glucose residues at the end of long glucose polymers, releasing alpha-D-glucose 1-phosphate. The nomenclature convention is to preface the name according to the natural substrate, as in glycogen phosphorylase, starch phosphorylase, maltodextrin phosphorylase, etc. Name differences among these substrates reflect differences in patterns of branching with alpha 1,6 linkages. Members include allosterically regulated and unregulated forms. A related family, TIGR02094, contains examples known to act well on particularly small alpha 1,4 glucans, as may be found after import from exogenous sources [Energy metabolism, Biosynthesis and degradation of polysaccharides]. | ||
| pfam00343 | Phosphorylase | 0 | 114 | 836 | 728 | + Carbohydrate phosphorylase. The members of this family catalyze the formation of glucose 1-phosphate from one of the following polyglucoses; glycogen, starch, glucan or maltodextrin. | ||
| PRK14985 | PRK14985 | 0 | 87 | 833 | 756 | + maltodextrin phosphorylase; Provisional | ||
| PRK14986 | PRK14986 | 0 | 55 | 836 | 791 | + glycogen phosphorylase; Provisional | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004645 | phosphorylase activity |
| GO:0005975 | carbohydrate metabolic process |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1z8d_A | 0 | 14 | 836 | 12 | 829 | A Chain A, Crystal Structure Of Human Muscle Glycogen Phosphorylase A With Amp And Glucose |
| PDB | 2gj4_A | 0 | 15 | 836 | 1 | 817 | A Chain A, Structure Of Rabbit Muscle Glycogen Phosphorylase In Complex With Ligand |
| PDB | 4el5_A | 0 | 15 | 836 | 1 | 817 | A Chain A, Structure Of Rabbit Muscle Glycogen Phosphorylase In Complex With Ligand |
| PDB | 4el0_A | 0 | 15 | 836 | 1 | 817 | A Chain A, Structure Of Rabbit Muscle Glycogen Phosphorylase In Complex With Ligand |
| PDB | 4eky_A | 0 | 15 | 836 | 1 | 817 | A Chain A, Structure Of Rabbit Muscle Glycogen Phosphorylase In Complex With Ligand |
| Hydropathy |
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| Sequence Alignments (This image is cropped. Click for full image.) |
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