y
Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 487158 |
Family | GT47 |
Protein Properties | Length: 520 Molecular Weight: 58786.4 Isoelectric Point: 9.2463 |
Chromosome | Chromosome/Scaffold: 6 Start: 1199343 End: 1202333 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 188 | 469 | 0 |
EKQFKIYVYKEGEPPLFHDGPCKSIYSMEGSFIYEMETDTRFRTNNPDKAHAFYLPFSVVKMVRYVYERNSRDFSPIRNTVRDYINLVGDKYPYWNRSIG ADHFILSCHDWGPEASFSHPHLGHNSIRALCNANTSEKFKPRKDVSIPEINLRTGSLTGLVGGPSPSSRPILAFFAGGVHGPVRPVLLEHWENKDNDIRV HKYLPRGTSYSDMMRNSKFCICPSGYEVASPRIVEALYSGCVPVLINSGYVPPFSDVLNWRSFSVIVSVEDIPNLKTILTAI |
Full Sequence |
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Protein Sequence Length: 520 Download |
MGDEDVDGKC RNMSACSSTT SYSTKLFLFM VPLVVISAFV FVNIGPKTPT SFLTSLSTSS 60 HHLPPSPSLP PAPAPALSPL PPEMLPSLSA SSLSTKVESI QDDYNRTIQM NLINVTTTSS 120 NVTSTASLEP KKRRVLSNLE KIEFELQKAR ASIKAASMDD PVDDPDYVPL GPMYWNAKVF 180 HRSYLEMEKQ FKIYVYKEGE PPLFHDGPCK SIYSMEGSFI YEMETDTRFR TNNPDKAHAF 240 YLPFSVVKMV RYVYERNSRD FSPIRNTVRD YINLVGDKYP YWNRSIGADH FILSCHDWGP 300 EASFSHPHLG HNSIRALCNA NTSEKFKPRK DVSIPEINLR TGSLTGLVGG PSPSSRPILA 360 FFAGGVHGPV RPVLLEHWEN KDNDIRVHKY LPRGTSYSDM MRNSKFCICP SGYEVASPRI 420 VEALYSGCVP VLINSGYVPP FSDVLNWRSF SVIVSVEDIP NLKTILTAIS PRQYLRMYRR 480 VLKVRRHFEV NSPAKRFDVF HMILHSIWVR RLNVRIREV* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-67 | 187 | 469 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
DDBJ | BAB08605.1 | 0 | 112 | 519 | 1 | 408 | unnamed protein product [Arabidopsis thaliana] |
RefSeq | NP_001031828.1 | 0 | 1 | 519 | 1 | 518 | unknown protein [Arabidopsis thaliana] |
RefSeq | XP_002284018.1 | 0 | 187 | 518 | 1 | 332 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002326234.1 | 0 | 187 | 514 | 1 | 328 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002528630.1 | 0 | 114 | 518 | 157 | 567 | catalytic, putative [Ricinus communis] |