Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 488861 |
Family | GT47 |
Protein Properties | Length: 611 Molecular Weight: 70360 Isoelectric Point: 9.8213 |
Chromosome | Chromosome/Scaffold: 6 Start: 8306799 End: 8312782 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 279 | 561 | 0 |
RILKVYVYKEGNRPIFHTPILKGLYASEGWFMKLMEGNKQYTVKDPRKAHLYYMPFSARMLEYTLYVRNSHNRTNLRQFLKEYTEHISSKYPFFNRTDGA DHFLVACHDWAPYETRHHMEHCIKALCNADVTAGFKIGRDISLPETYVRAAKNPLRDLGGKPPSQRRTLAFYAGSMHGYLRQILLQHWKDKDPDMKIFGR MPFGVASKMNYIEQMKSSKYCICPKGYEVNSPRVVESIFYECVPVIISDNFVPPFFEVLDWSAFSVIVAEKDIPRLKDILSSI |
Full Sequence |
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Protein Sequence Length: 611 Download |
MEIIRSELRK HSRSGKRKWA ILVGIMAFTY ILLLLSYGDA LRYLLPDGRR LKLPNENNAL 60 MTPSRNTLAV NFSEDSAGSG IHVLEKNGNV SDFGLRNESE DDEEGFVGNV DFESFEDAKD 120 SIIIKEVAGS SDSLFPTEKT VMQNEIVSTS NNGHQVQNVS VQSQKNLKSS MSSAGSSIAG 180 SAFGNSSLLV SRKVSKKKKM RCDLPPKSVT TIDEMNRILA RHRRTSRAMV CVQLRDEEIL 240 TARKEIENAP PVATSERQLY PPIFRNVSMF KRSYELMERI LKVYVYKEGN RPIFHTPILK 300 GLYASEGWFM KLMEGNKQYT VKDPRKAHLY YMPFSARMLE YTLYVRNSHN RTNLRQFLKE 360 YTEHISSKYP FFNRTDGADH FLVACHDWAP YETRHHMEHC IKALCNADVT AGFKIGRDIS 420 LPETYVRAAK NPLRDLGGKP PSQRRTLAFY AGSMHGYLRQ ILLQHWKDKD PDMKIFGRMP 480 FGVASKMNYI EQMKSSKYCI CPKGYEVNSP RVVESIFYEC VPVIISDNFV PPFFEVLDWS 540 AFSVIVAEKD IPRLKDILSS IPEEKYVKMQ MAVRKAQRHF LWHAKPEKYD LFHMVLHSIW 600 YNRVFQVKRR * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 7.0e-66 | 281 | 561 | 301 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAN76867.1 | 0 | 17 | 606 | 725 | 1390 | hypothetical protein [Vitis vinifera] |
EMBL | CAN76867.1 | 0 | 210 | 608 | 264 | 711 | hypothetical protein [Vitis vinifera] |
RefSeq | NP_197468.1 | 0 | 4 | 610 | 3 | 600 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002283936.1 | 0 | 204 | 610 | 1 | 410 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002514248.1 | 0 | 37 | 610 | 39 | 676 | catalytic, putative [Ricinus communis] |