| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 491427 |
| Family | GT47 |
| Protein Properties | Length: 584 Molecular Weight: 67433.4 Isoelectric Point: 7.454 |
| Chromosome | Chromosome/Scaffold: 7 Start: 3636066 End: 3638444 |
| Description | Exostosin family protein |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 254 | 537 | 0 |
| EKKLKVYVYREGKRPVLHKPVLKGIYASEGWFMKQLKSSRTFVTKDPRKAHLFYLPFSSKMLEETLYVPGSHSDQNLIQFLKNYLDMISSKYNFWNKTGG SDHFLVACHDWAPSETRQYMAKCIRALCNSDVSEGFVFGKDVALPETTILVPRRPLRALGGKPVSQRQILAFFAGGMHGYLRPLLLRNWGGNRDPDMKIF SEIPKSKGKKSYMEYMKSSKFCICPKGHEVNSPRVVEALFYECVPVIISDNFVPPFFEVLNWEAFAVFVLEKDIPDLKNILVSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 584 Download |
| MLNLWEQLLV YESEEAMKLL RFAGLVFIFI STFQFVNIRY YGGSMFSLSS QDKFPVSSSI 60 DVSTEPVRTL SGPERLNFSS SRSIEVDEEE STGLEEDHVI GSDKNDTVQA HDSFIEDVKD 120 KETLDLLPGI RSSTNETYEK IVEDADTAFE NTRKVEILES KTDPSVDNLS SEVKKFMKVS 180 NSGVVSITEM MNLLHQSRTS HVSLKLKRSS TVDQELLYAR TQIENPPLIE NDPLLHTPLY 240 WNLSMFKRSY ELMEKKLKVY VYREGKRPVL HKPVLKGIYA SEGWFMKQLK SSRTFVTKDP 300 RKAHLFYLPF SSKMLEETLY VPGSHSDQNL IQFLKNYLDM ISSKYNFWNK TGGSDHFLVA 360 CHDWAPSETR QYMAKCIRAL CNSDVSEGFV FGKDVALPET TILVPRRPLR ALGGKPVSQR 420 QILAFFAGGM HGYLRPLLLR NWGGNRDPDM KIFSEIPKSK GKKSYMEYMK SSKFCICPKG 480 HEVNSPRVVE ALFYECVPVI ISDNFVPPFF EVLNWEAFAV FVLEKDIPDL KNILVSITEE 540 RYREMQTRVK MVQKHFLWHS KPERFDIFHM ILHSIWYNRV FQS* |
| Functional Domains Download unfiltered results here | ||||||
|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description |
| pfam03016 | Exostosin | 3.0e-71 | 253 | 537 | 305 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_195005.1 | 0 | 1 | 582 | 1 | 592 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | NP_197954.1 | 0 | 172 | 582 | 237 | 651 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002281263.1 | 0 | 127 | 582 | 217 | 665 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002309547.1 | 0 | 140 | 582 | 20 | 467 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002324801.1 | 0 | 190 | 582 | 1 | 394 | predicted protein [Populus trichocarpa] |
