Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 493201 |
Family | GT47 |
Protein Properties | Length: 541 Molecular Weight: 62672.8 Isoelectric Point: 10.1889 |
Chromosome | Chromosome/Scaffold: 7 Start: 11853012 End: 11855204 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 198 | 483 | 0 |
LKVYIYPDGEKPIFHQPHLNGIYASEGWFMKLMESNTQFVTKNPERAHLFYMPYSVKQLQTSIFVPGSHNIKPLSIFLRDYVNMLSTKYPFWNRTHGSDH FLVACHDWGPYTVNEHPELRRNTIKALCNADLADGIFIPGKDVSLPETSIRNAGKPLRNIGNGNRVSQRPILAFFAGNLHGRVRPKLLKHWRNKDDDMKI YGPLPHNVARKMTYVQHMKSSKYCLCPMGYEVNSPRIVEAIYYECVPVVIADNFMLPFSDVLDWSAFSVVVPEKEIPRLKEILLEI |
Full Sequence |
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Protein Sequence Length: 541 Download |
MVNIKSPLRL FIEDSIKELI RGFRRQRIKW RNAFLLGSIM TTIVVLLHTP TFSVFSDEEE 60 TESSSPIYLN GSLHLNIQIV SSDAKVENLH ALRTRTPIVQ LNASEASGTV ILRKRRKRKK 120 RKKTKDELIL PDPPPAQPRV LSSSERRALS LPPKKALTYA KLEIQRAPEI INDTDLFAPL 180 FRNLSVFKRS YELMELILKV YIYPDGEKPI FHQPHLNGIY ASEGWFMKLM ESNTQFVTKN 240 PERAHLFYMP YSVKQLQTSI FVPGSHNIKP LSIFLRDYVN MLSTKYPFWN RTHGSDHFLV 300 ACHDWGPYTV NEHPELRRNT IKALCNADLA DGIFIPGKDV SLPETSIRNA GKPLRNIGNG 360 NRVSQRPILA FFAGNLHGRV RPKLLKHWRN KDDDMKIYGP LPHNVARKMT YVQHMKSSKY 420 CLCPMGYEVN SPRIVEAIYY ECVPVVIADN FMLPFSDVLD WSAFSVVVPE KEIPRLKEIL 480 LEIPMRRYLK MQSNVKMVQR HFLWSPKPRK YDVFHMILHS IWFNLLNQNQ TSFDDHNPDS 540 * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-70 | 198 | 483 | 302 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CAB10449.1 | 0 | 24 | 540 | 512 | 1024 | limonene cyclase like protein [Arabidopsis thaliana] |
EMBL | CBI23466.1 | 0 | 27 | 538 | 15 | 542 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_567512.2 | 0 | 1 | 540 | 1 | 542 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002269459.1 | 0 | 27 | 532 | 15 | 536 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002530666.1 | 0 | 65 | 530 | 54 | 524 | catalytic, putative [Ricinus communis] |