Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 494490 |
Family | GT47 |
Protein Properties | Length: 477 Molecular Weight: 54124.1 Isoelectric Point: 9.6808 |
Chromosome | Chromosome/Scaffold: 8 Start: 2846476 End: 2875035 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 67 | 384 | 0 |
RKTKVYMYDLPTNFTHGVIQQHGGEKSDDVTGLKYPGHQHMHYHFHGRINGSARMDRALIPFSSHLSNVGSFSTLTRPEIERVGSPIVRVFDPAEADLFF VAAFSSLSLIVNSDRPEFGSGFGYSEEVMQESLVSWLEGQEWCRRNNGRDHVIVAGDPNALNRVMDRVKNAVLLVTDLGWFRADQGSLVKDVIIPYSHRV DAYEGELGVKQRNNLLYRETSHNLLGSVLVYGLALNVKYGGRVRDLLFKLLENEEDVVIKHGTQSRENRRAAKQGMHTSKFCLHSAGDTHSACRLFDALA SLCVPVIVSDGIELPFED |
Full Sequence |
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Protein Sequence Length: 477 Download |
MKEKLNPKIR KPNNSSSKKV TVSFLSVFFV FVFVNTFFYP SFYSDSGSIR RNLVDSRESF 60 DFPEKLRKTK VYMYDLPTNF THGVIQQHGG EKSDDVTGLK YPGHQHMHYH FHGRINGSAR 120 MDRALIPFSS HLSNVGSFST LTRPEIERVG SPIVRVFDPA EADLFFVAAF SSLSLIVNSD 180 RPEFGSGFGY SEEVMQESLV SWLEGQEWCR RNNGRDHVIV AGDPNALNRV MDRVKNAVLL 240 VTDLGWFRAD QGSLVKDVII PYSHRVDAYE GELGVKQRNN LLYRETSHNL LGSVLVYGLA 300 LNVKYGGRVR DLLFKLLENE EDVVIKHGTQ SRENRRAAKQ GMHTSKFCLH SAGDTHSACR 360 LFDALASLCV PVIVSDGIEL PFEDDAALKP GFVVKKLRKV KPEKILKYQK AMKEVRRYFD 420 YTHPNGSVNE IWRQVTKKIP LIKLMINREK RMIKREGSDL QCSCLCLNQT GIIHGV* 480 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 2.0e-50 | 70 | 384 | 324 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
RefSeq | NP_199306.1 | 0 | 5 | 476 | 1 | 443 | ARAD2 (ARABINAN DEFICIENT 2); catalytic [Arabidopsis thaliana] |
RefSeq | NP_850241.1 | 0 | 68 | 476 | 59 | 447 | ARAD1 (ARABINAN DEFICIENT 1); catalytic/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
RefSeq | XP_002318294.1 | 0 | 73 | 472 | 1 | 378 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002322391.1 | 0 | 23 | 473 | 15 | 454 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002523645.1 | 0 | 18 | 473 | 10 | 449 | catalytic, putative [Ricinus communis] |