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Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 496352 |
Family | GT47 |
Protein Properties | Length: 418 Molecular Weight: 47503 Isoelectric Point: 7.4947 |
Chromosome | Chromosome/Scaffold: 8 Start: 20202132 End: 20204425 |
Description | Exostosin family protein |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 50 | 345 | 0 |
RLKVFVYELPSKYNKKILQKDPRCLNHMFAAEIYMQRFLLSSPVRTLNPEEADWFYVPVYTTCDLTPNGLPLPFKSPRMMRSAIQLIASNWPYWNRTEGA DHFFVVPHDFGACFHYQEEKAIGRGILPLLQRATLVQTFGQRNHVCLKEGSITVPPYAPPQKMQSHLIPEKTPRSIFVYFRGLFYDVGNDPEGGYYARGA RAAVWENFKDNPLFDISTEHPTTYYEDMQRAIFCLCPLGWAPWSPRLVEAVIFGCIPVIIADDIVLPFADAIPWEDIGVFVDEKDVPYLDTILTSI |
Full Sequence |
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Protein Sequence Length: 418 Download |
MKLSSWVLIF LLCNLTFLSS ISAFRLSRSQ PTERISGSAG DVLEDNPVGR LKVFVYELPS 60 KYNKKILQKD PRCLNHMFAA EIYMQRFLLS SPVRTLNPEE ADWFYVPVYT TCDLTPNGLP 120 LPFKSPRMMR SAIQLIASNW PYWNRTEGAD HFFVVPHDFG ACFHYQEEKA IGRGILPLLQ 180 RATLVQTFGQ RNHVCLKEGS ITVPPYAPPQ KMQSHLIPEK TPRSIFVYFR GLFYDVGNDP 240 EGGYYARGAR AAVWENFKDN PLFDISTEHP TTYYEDMQRA IFCLCPLGWA PWSPRLVEAV 300 IFGCIPVIIA DDIVLPFADA IPWEDIGVFV DEKDVPYLDT ILTSIPPEVI LRKQRLLANP 360 SMKQAMLFPQ PAQPGDAFHQ VLNGLARKLP HERSVYLRPG EKLLNWTAGP VADLKPW* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 3.0e-79 | 50 | 345 | 304 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |