| Basic Information | |
|---|---|
| Species | Ricinus communis |
| Cazyme ID | 58439.m000009 |
| Family | PL8 |
| Protein Properties | Length: 269 Molecular Weight: 30932.4 Isoelectric Point: 5.3361 |
| Chromosome | Chromosome/Scaffold: 58439 Start: 262 End: 1069 |
| Description | |
| View CDS | |
| External Links |
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| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
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| Family | Start | End | Evalue |
| PL8 | 1 | 241 | 0 |
| MNNENLHGWFTSDGMFYLYNNDLGHYSENYWATVNPYRLPGTTETEQKPLEGTPENIKTNYQQVGMTSLSDDAFVASKKLNNTSALAAMTFTNWNKSLTL NKGWFILGNKIIFVGSNIKNQSSHKAYTTIEQRKENQKHPYCSYVNNQPIDLNNQLVDFTNTKSIFLESDDPAQNIGYYFFKPTTLSISKALQTGKWQNI KADDKSPEAIKEVSNTFITIMQNHTQDGDRYAYMMLPNMTR | |||
| Full Sequence |
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| Protein Sequence Length: 269 Download |
| MNNENLHGWF TSDGMFYLYN NDLGHYSENY WATVNPYRLP GTTETEQKPL EGTPENIKTN 60 YQQVGMTSLS DDAFVASKKL NNTSALAAMT FTNWNKSLTL NKGWFILGNK IIFVGSNIKN 120 QSSHKAYTTI EQRKENQKHP YCSYVNNQPI DLNNQLVDFT NTKSIFLESD DPAQNIGYYF 180 FKPTTLSISK ALQTGKWQNI KADDKSPEAI KEVSNTFITI MQNHTQDGDR YAYMMLPNMT 240 RQEFETYISK LDIDLLENND KLAAVYDHD |
| Functional Domains Download unfiltered results here | ||||||||
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| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam02278 | Lyase_8 | 5.0e-67 | 1 | 244 | 245 | + Polysaccharide lyase family 8, super-sandwich domain. This family consists of a group of secreted bacterial lyase enzymes EC:4.2.2.1 capable of acting on hyaluronan and chondroitin in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. | ||
| cd01083 | GAG_Lyase | 9.0e-85 | 1 | 269 | 274 | + Glycosaminoglycan (GAG) polysaccharide lyase family. This family consists of a group of secreted bacterial lyase enzymes capable of acting on glycosaminoglycans, such as hyaluronan and chondroitin, in the extracellular matrix of host tissues, contributing to the invasive capacity of the pathogen. These are broad-specificity glycosaminoglycan lyases which recognize uronyl residues in polysaccharides and cleave their glycosidic bonds via a beta-elimination reaction to form a double bond between C-4 and C-5 of the non-reducing terminal uronyl residues of released products. Substrates include chondroitin, chondroitin 4-sulfate, chondroitin 6-sulfate, and hyaluronic acid. Family members include chondroitin AC lyase, chondroitin abc lyase, xanthan lyase, and hyalurate lyase. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005576 | extracellular region |
| GO:0016829 | lyase activity |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1n7r_A | 0 | 1 | 267 | 410 | 660 | A Chain A, Streptococcus Pneumoniae Hyaluronate Lyase W291a/w292a/f343v Mutant Complex With Hexasaccharide Hyaluro |
| PDB | 1n7n_A | 0 | 1 | 267 | 410 | 660 | A Chain A, Streptococcus Pneumoniae Hyaluronate Lyase W292a Mutant |
| PDB | 1n7q_A | 0 | 1 | 267 | 410 | 660 | A Chain A, Streptococcus Pneumoniae Hyaluronate Lyase W291aW292A DOUBLE MUTANT Complex With Hyaluronan Hexasacchride |
| PDB | 1n7p_A | 0 | 1 | 267 | 410 | 660 | A Chain A, Streptococcus Pneumoniae Hyaluronate Lyase W292aF343V Double Mutant |
| PDB | 1lxk_A | 0 | 1 | 267 | 410 | 660 | A Chain A, Streptococcus Pneumoniae Hyaluronate Lyase W292aF343V Double Mutant |
| Hydropathy |
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