| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 894960 |
| Family | GT24 |
| Protein Properties | Length: 1617 Molecular Weight: 182264 Isoelectric Point: 5.5287 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT24 | 1303 | 1550 | 0 |
| INIFSIASGHLYERFLKIMILSVLKNTNRPVKFWFIKNYLSPQFKDVIPHMAQEYNFEYELITYKWPSWLHKQKEKQRIIWAYKILFLDVIFPLSLEKVI FVDADQIIRTDMGELYDMDIKGRPLAYTPFCDNNREMDGYRFWRQGFWKEHLRGRPYHISALYVVDLVKFRETAAGDNLRVFYETLSKDPNSLSNLDQDL PNYAQHTVPIFSLPQEWLWCESWCGNATKAKARTIDLCNNPMTKEPKL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 1617 Download |
| MGTTNLRSWL YLILLFFVVV GVNAQNRRPK NVQVAVKAKW QGTPLLLEAG ELISKESKQL 60 FWEFTDAWLG SDGDDTGDSD CKSARDCLLK ISKQASTLLA QPVASLFHFS LTLRSASPRL 120 VLYRQLADES LSSFPHGDDP SATDCCCVDT GSSLFYDVAD LQSWLASAPA AGDAVQGPEL 180 FDFDHVHFDS RAGSPVAVLY GAVGTDCFRK FHLSLAKAAK EGKVTYVVRP VLPLGCEGKT 240 RPCGAIGARE NVSLAGYGVE LALKNMEYKA MDDSAIKKGI TLEDPRTEDL SQDVRGFIFS 300 KILDRKPELR SEVMAFRDYL LSSTVSDTLD VWELKDLGHQ TAQRIVHASD PLQSMQEINQ 360 NFPSVVSSLS RMKLNESIKE EILSNQRMVP PGKALLALNG ALLNIEDMDL YMLMDLAHQE 420 LSLANHFSKL KIPDGAIRKL LLTTPLPEPD SYRVDFRSVH VTYLNNLEED DMYKRWRSNI 480 NEILMPAFPG QLRYIRKNLF HAVYVIDPAT PCGLESIDTL RSLYENQLPV RFGVILYSTQ 540 LIKNIEQNGG QIPSSDAATN AQVKEDISTM VIRLFLYIKE HHGIQTAFQF LGNVNTLRTE 600 SADSSEEDIE QEHVDGAFVE TILPKVKTPP QDILLKLQQE HTLKEASEAS SMFVFKLGLA 660 KLKCSFLMNG LVFDSIEEET LLNAMNDELP KIQEQVYYGQ IESRTNVLDK LLSESGLSRY 720 NPQIISGGKN KPRFVSLASS TRKGESMLND VNYLHSPETS EDVKYVTHLL AADVATKKGT 780 KLLHEGIRYL IGGSKSARLG VLFSSQNADP YSLLFIKFFE KTASSFSHKE KVLYFLDKLC 840 LFYEREYLLK TAVESASSQM FIDKVLELAE EYGLSSKAYR SCLVESLDEE LLKRLTKVAQ 900 FLSWELGLES DANAIISNGR VIFPVDERTF LGQDLHLLES MEFNQRVKPV QEIIEGIEWQ 960 DVDPDLLTSK YFSDVFMFVS SAMATRDRSS ESARFEVLNS EYSAVLLGNE NATIHIDAVI 1020 DPLSPTGQKL ASLLQVLQKH VQTSMRIVLN PMSSLVDIPL KNYYRYVLPN TDDYSNTGFD 1080 VDGPKAFFAN MPLSKTLTMN LDVPEPWLVE PVIAIHDLDN ILLENLGDTT TLQAVFEVES 1140 LVLTGHCAEK DHEAPRGLQL ILGTKNRPHL VDTLVMANLG YWQMKVSPGV WYLQLAPGRS 1200 SELYTLKGGN DGSQDQSSLK RITIDDLRGK VVHLEVVKRK GKEHEKLLVP SDGDDGVQQN 1260 NKRGSWNSNF LKWASGFVGG RQQSMKGGPE KEHEKGGRQG KTINIFSIAS GHLYERFLKI 1320 MILSVLKNTN RPVKFWFIKN YLSPQFKDVI PHMAQEYNFE YELITYKWPS WLHKQKEKQR 1380 IIWAYKILFL DVIFPLSLEK VIFVDADQII RTDMGELYDM DIKGRPLAYT PFCDNNREMD 1440 GYRFWRQGFW KEHLRGRPYH ISALYVVDLV KFRETAAGDN LRVFYETLSK DPNSLSNLDQ 1500 DLPNYAQHTV PIFSLPQEWL WCESWCGNAT KAKARTIDLC NNPMTKEPKL QGARRIVTEW 1560 PDLDLEARKF TAKILGEDVE LVNEPVAAPA TDKPNPPPSS DISKDTEQDL ESKAEL* 1620 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam01501 | Glyco_transf_8 | 7.0e-5 | 1307 | 1502 | 206 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| cd04194 | GT8_A4GalT_like | 6.0e-15 | 1303 | 1519 | 227 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
| cd00505 | Glyco_transf_8 | 3.0e-57 | 1303 | 1550 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| pfam06427 | UDP-g_GGTase | 1.0e-82 | 973 | 1178 | 212 | + UDP-glucose:Glycoprotein Glucosyltransferase. The N-terminal region of this group of proteins is required for correct folding of the ER UDP-Glc: glucosyltransferase. | ||
| cd06432 | GT8_HUGT1_C_like | 4.0e-177 | 1303 | 1550 | 248 | + The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family. C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003980 | UDP-glucose:glycoprotein glucosyltransferase activity |
| GO:0006486 | protein glycosylation |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG51883.1 | 0 | 1 | 1616 | 1 | 1674 | AC016162_4 putative UDP-glucose:glycoprotein glucosyltransferase; 101200-91134 [Arabidopsis thaliana] |
| GenBank | EEC73742.1 | 0 | 27 | 1601 | 35 | 1664 | hypothetical protein OsI_08377 [Oryza sativa Indica Group] |
| RefSeq | NP_177278.3 | 0 | 1 | 1616 | 1 | 1613 | EBS1 (EMS-mutagenized bri1 suppressor 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002268972.1 | 0 | 1 | 1616 | 1 | 1611 | PREDICTED: similar to EBS1 (EMS-MUTAGENIZED BRI1 SUPPRESSOR 1); UDP-glucose:glycoprotein glucosyltransferase/ transferase, transferring glycosyl groups / transferase, transferring hexosyl groups [Vitis vinifera] |
| RefSeq | XP_002529534.1 | 0 | 1 | 1500 | 1 | 1499 | UDP-glucose glycoprotein:glucosyltransferase, putative [Ricinus communis] |
