| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 905093 |
| Family | GT8 |
| Protein Properties | Length: 365 Molecular Weight: 41175.9 Isoelectric Point: 6.7288 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT8 | 69 | 329 | 0 |
| AVHIAMTLDPAYLRGTVSAVHSILKHTSCPQNIFFHFIASGSSHGSLVKTLSSVFPSLSFKVYTFDETMVKNLISSSIRQALDSPLNYARSYLSEILSSC VSRVIYLDSDVIVVDDIQKLWKISLSGSRTIGAPEYCHANFTKYFTESFWSDRKLSSVFDSKTPCYFNTGVMVIDLDRWREGDYTRKIENWMKIQKEDKR IYELGSLPPFLLVFGGDIEAIDHQWNQHGLGGDNIVSSCRSLHPGPVSLIHWSGKGKPWVR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 365 Download |
| MMSSSRLVSR LIIFSIISTA FFSVESIRLF PDSFDDASSD FTEAPAYQNG LECSVLAKNR 60 LLLACDPSAV HIAMTLDPAY LRGTVSAVHS ILKHTSCPQN IFFHFIASGS SHGSLVKTLS 120 SVFPSLSFKV YTFDETMVKN LISSSIRQAL DSPLNYARSY LSEILSSCVS RVIYLDSDVI 180 VVDDIQKLWK ISLSGSRTIG APEYCHANFT KYFTESFWSD RKLSSVFDSK TPCYFNTGVM 240 VIDLDRWREG DYTRKIENWM KIQKEDKRIY ELGSLPPFLL VFGGDIEAID HQWNQHGLGG 300 DNIVSSCRSL HPGPVSLIHW SGKGKPWVRL DDGKPCPIDY LWAPYDLHKS QRQYLQYNQE 360 LEIL* 420 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00505 | Glyco_transf_8 | 1.0e-23 | 77 | 329 | 257 | + Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+. | ||
| PLN02742 | PLN02742 | 5.0e-24 | 152 | 345 | 194 | + Probable galacturonosyltransferase | ||
| cd04194 | GT8_A4GalT_like | 2.0e-26 | 70 | 327 | 266 | + A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS. | ||
| cd06429 | GT8_like_1 | 9.0e-33 | 70 | 330 | 284 | + GT8_like_1 represents a subfamily of GT8 with unknown function. A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. | ||
| pfam01501 | Glyco_transf_8 | 4.0e-66 | 71 | 331 | 264 | + Glycosyl transferase family 8. This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG43554.1 | 0 | 11 | 349 | 9 | 348 | AF211536_1 Avr9/Cf-9 rapidly elicited protein 231 [Nicotiana tabacum] |
| RefSeq | NP_189474.2 | 0 | 1 | 364 | 1 | 365 | GATL10 (Galacturonosyltransferase-like 10); polygalacturonate 4-alpha-galacturonosyltransferase/ transferase, transferring hexosyl groups [Arabidopsis thaliana] |
| RefSeq | XP_002271160.1 | 0 | 26 | 361 | 25 | 369 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002311853.1 | 0 | 41 | 348 | 47 | 359 | glycosyltransferase, CAZy family GT8 [Populus trichocarpa] |
| RefSeq | XP_002517421.1 | 0 | 22 | 362 | 20 | 361 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1ss9_A | 0.0000006 | 156 | 329 | 84 | 254 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
| PDB | 1ga8_A | 0.0000006 | 156 | 329 | 84 | 254 | A Chain A, Crystal Structural Analysis Of Active Site Mutant Q189e Of Lgtc |
| PDB | 1g9r_A | 0.0000006 | 156 | 329 | 84 | 254 | A Chain A, Crystal Structure Of Galactosyltransferase Lgtc In Complex With Mn And Udp-2f-Galactose |
