| Basic Information | |
|---|---|
| Species | Arabidopsis lyrata |
| Cazyme ID | 908336 |
| Family | GT64 |
| Protein Properties | Length: 766 Molecular Weight: 86413.7 Isoelectric Point: 8.9832 |
| View CDS | |
| External Links |
|---|
| NCBI Taxonomy |
| Plaza |
| CAZyDB |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT64 | 518 | 752 | 0 |
| FTLATMTYDARLWNLKMYVKRYSRCPSVKEIVVIWNKGPPPELTELDSAVPVRIRVQKQNSLNNRFEIDPLIKTRAVLELDDDIMMPCDDIEKGFRVWRE HPERLVGFYPRFVDQTMTYSAEKFARSHKGYNMILTGAAFMDVRFAFDMYQSDKAKLGREFVGEQFNCEDILLNFLYANASGWGKAVEYVRPSLVTIDTS KFSGVAISGNTNQHYRKRSKCLRRFSDLYGSLADR | |||
| Full Sequence |
|---|
| Protein Sequence Length: 766 Download |
| MMEETTENAG KLSSQKNVAA SGHNHHNRYK YLSNYGAGRR FLFFASCFGV YALVAATYAW 60 FVFPPHIGRT DHVSSSSLGC REDNEGSWSI GVFYGDSPFS LKPIETINVW RNESGAWPVA 120 NPVITCASFT NAGLPSNFVA DPFLYVQGDT LYLFFETKSP ITMQGDIGVA KSIDKGATWE 180 PLGIALDEAW HLSFPFVFNY NGEIFMMPES NEIGQLNLYR AVNFPLSWKL EKVILKKPLV 240 DSTLIHHEGI YWLFGSDHSS FGAKKNGQLE IWYSSSPLGT WKPHKKNPIY NGNRSVGARN 300 GGRAFLYDGN LYRVGQDCGE NYGKRIRVFK IEVLSKEEYR EVEVPFSFEA SHKGKNSWNG 360 VRQHHFDVKQ LSSGEFIGLL DGDRVTSGDL FHRVILGYAS LAAAISVVIL LGFLLGVVNC 420 IVPSTWCMNY YAGKRTDALL NLETAGLFSE KLRRIGSRLN RVPPFLRGFV KPNSSMGKFT 480 LGVIVLVGLL LTCVGVRYIY GGSGTVEPYP FKGHLSQFTL ATMTYDARLW NLKMYVKRYS 540 RCPSVKEIVV IWNKGPPPEL TELDSAVPVR IRVQKQNSLN NRFEIDPLIK TRAVLELDDD 600 IMMPCDDIEK GFRVWREHPE RLVGFYPRFV DQTMTYSAEK FARSHKGYNM ILTGAAFMDV 660 RFAFDMYQSD KAKLGREFVG EQFNCEDILL NFLYANASGW GKAVEYVRPS LVTIDTSKFS 720 GVAISGNTNQ HYRKRSKCLR RFSDLYGSLA DRIWEFGGRK DGWDL* 780 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd08978 | GH_F | 0.002 | 107 | 332 | 252 | + Glycosyl hydrolase families 43 and 62 form CAZY clan GH-F. This glycosyl hydrolase clan F (according to carbohydrate-active enzymes database (CAZY)) includes family 43 (GH43) and 62 (GH62). GH43 includes enzymes with beta-xylosidase (EC 3.2.1.37), beta-1,3-xylosidase (EC 3.2.1.-), alpha-L-arabinofuranosidase (EC 3.2.1.55), arabinanase (EC 3.2.1.99), xylanase (EC 3.2.1.8), endo-alpha-L-arabinanases (beta-xylanases) and galactan 1,3-beta-galactosidase (EC 3.2.1.145) activities. GH62 includes enzymes characterized as arabinofuranosidases (alpha-L-arabinofuranosidases; EC 3.2.1.55) that specifically cleave either alpha-1,2 or alpha-1,3-L-arabinofuranose side chains from xylans. GH43 are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. Many of the enzymes in this family display both alpha-L-arabinofuranosidase and beta-D-xylosidase activity using aryl-glycosides as substrates. GH62 are also predicted to be inverting enzymes. A common structural feature of both, GH43 and GH62 enzymes, is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller. | ||
| pfam09258 | Glyco_transf_64 | 2.0e-82 | 518 | 747 | 238 | + Glycosyl transferase family 64 domain. Members of this family catalyze the transfer reaction of N-acetylglucosamine and N-acetylgalactosamine from the respective UDP-sugars to the non-reducing end of [glucuronic acid]beta 1-3[galactose]beta 1-O-naphthalenemethanol, an acceptor substrate analog of the natural common linker of various glycosylaminoglycans. They are also required for the biosynthesis of heparan-sulphate. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0016758 | transferase activity, transferring hexosyl groups |
| GO:0031227 | intrinsic to endoplasmic reticulum membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CAB85556.1 | 0 | 2 | 765 | 1 | 764 | putative protein [Arabidopsis thaliana] |
| RefSeq | NP_196070.2 | 0 | 1 | 765 | 1 | 765 | glycosyltransferase family protein 47 [Arabidopsis thaliana] |
| RefSeq | XP_002262646.1 | 0 | 76 | 765 | 69 | 756 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002315348.1 | 0 | 65 | 765 | 86 | 847 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002532924.1 | 0 | 76 | 765 | 17 | 704 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1on8_B | 4e-27 | 510 | 749 | 22 | 270 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 1on8_A | 4e-27 | 510 | 749 | 22 | 270 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 1on6_B | 4e-27 | 510 | 749 | 22 | 270 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 1on6_A | 4e-27 | 510 | 749 | 22 | 270 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
| PDB | 1omz_B | 4e-27 | 510 | 749 | 22 | 270 | A Chain A, Arabidopsis Thaliana Peroxidase A2 |
