Basic Information | |
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Species | Arabidopsis lyrata |
Cazyme ID | 909677 |
Family | GT47 |
Protein Properties | Length: 511 Molecular Weight: 57955.7 Isoelectric Point: 9.57 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GT47 | 117 | 426 | 0 |
IKVYVYEMPKKFTFDLLWLFHNTYKETSNATSNGSPVHRLIEQHSIDYWLWADLISPESERRLKSVVRVHKQQDADFFYVPFFTTISFFLLEKQQCKALY REALKWVTDQPAWKRSEGRDHIFPIHHPWSFKSVRKFVKNAIWLLPDMDSTGNWYKPGQVSLEKDLILPYVPNVDICDAKCLSESAPMRTTLLFFRGRLK RNAGGKIRAKLGAELSGVKGVIISEGTAGEGGKLAAQGGMRRSLFCLCPAGDTPSSARLFDAIVSGCIPVIVSDELEFPFEGILDYKKVAVLVSSNDVVQ PGWLVNHLRS |
Full Sequence |
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Protein Sequence Length: 511 Download |
MSGKQQNHRS TSCRPRSKTL IIISLFSVSL LGILYTFSSS SRPSISNLNP SDQPETSFVT 60 SLEHFLTHKA PKLSLPVRDD TVRGESDDDV RKLDEMVFER ENRWLNEDPG YPVGFPIKVY 120 VYEMPKKFTF DLLWLFHNTY KETSNATSNG SPVHRLIEQH SIDYWLWADL ISPESERRLK 180 SVVRVHKQQD ADFFYVPFFT TISFFLLEKQ QCKALYREAL KWVTDQPAWK RSEGRDHIFP 240 IHHPWSFKSV RKFVKNAIWL LPDMDSTGNW YKPGQVSLEK DLILPYVPNV DICDAKCLSE 300 SAPMRTTLLF FRGRLKRNAG GKIRAKLGAE LSGVKGVIIS EGTAGEGGKL AAQGGMRRSL 360 FCLCPAGDTP SSARLFDAIV SGCIPVIVSD ELEFPFEGIL DYKKVAVLVS SNDVVQPGWL 420 VNHLRSLTPF QIKELQKNLA QYSRHFLYSS PAQPLGPEDL TWRMMAGKLV NIKLHTRRSQ 480 RVVKGSRSLC RCDCWKPNST AINPLNPLLS * |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
pfam03016 | Exostosin | 5.0e-66 | 116 | 426 | 319 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. |
Gene Ontology | |
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GO Term | Description |
GO:0016020 | membrane |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
EMBL | CBI20132.1 | 0 | 124 | 501 | 1 | 378 | unnamed protein product [Vitis vinifera] |
RefSeq | NP_197191.1 | 0 | 1 | 496 | 1 | 497 | exostosin family protein [Arabidopsis thaliana] |
RefSeq | XP_002285599.1 | 0 | 54 | 501 | 62 | 512 | PREDICTED: hypothetical protein [Vitis vinifera] |
RefSeq | XP_002325382.1 | 0 | 38 | 502 | 42 | 503 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002520033.1 | 0 | 49 | 501 | 51 | 503 | catalytic, putative [Ricinus communis] |