y
Basic Information | |
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Species | Medicago truncatula |
Cazyme ID | AC233660_28.1 |
Family | GH31 |
Protein Properties | Length: 398 Molecular Weight: 44795 Isoelectric Point: 6.9556 |
Chromosome | Chromosome/Scaffold: 2336602 Start: 118965 End: 121761 |
Description | alpha-xylosidase 1 |
View CDS |
External Links |
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NCBI Taxonomy |
Plaza |
CAZyDB |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
GH31 | 81 | 236 | 0 |
XTEELCNRWIEVGAFYPFSRDHSSVISPRQELYQWESVAESARNALGMRYKLLPYFYTINYEAHISGAPIARPLFFSFPNYIECYGLSTQFLLGSSLMIS PVLEPGKTEVKALFPPGTWYSLFDLTQVIVSKDGNYVTLDAPLHVVNVHLYQNTIL |
Full Sequence |
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Protein Sequence Length: 398 Download |
MDESGWLKML IHHDEAMYST PGLIPFLKRL RKVYKRKKEK NSFVCTGXXX XXXXXXXXXX 60 XXXXXXXXXX XXXXXXXXXX XTEELCNRWI EVGAFYPFSR DHSSVISPRQ ELYQWESVAE 120 SARNALGMRY KLLPYFYTIN YEAHISGAPI ARPLFFSFPN YIECYGLSTQ FLLGSSLMIS 180 PVLEPGKTEV KALFPPGTWY SLFDLTQVIV SKDGNYVTLD APLHVVNVHL YQNTILPMQQ 240 GGMVSKDARM TPFSLIVTFP AGANEGEAKG NLFLDDDEMP EMKVGNGYST YIDFHASVKE 300 GTVKIWSQVQ EGKFVLDKGL VIDTINVLGL NYGSGTLVSI EIDGEPSIGV SYVKVSTSEH 360 KYLFKQGDEE KKTVMVGIKG LNIPVGKRFA LTWKMGS* 420 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
PRK10426 | PRK10426 | 2.0e-18 | 82 | 223 | 145 | + alpha-glucosidase; Provisional | ||
PLN02763 | PLN02763 | 2.0e-19 | 82 | 291 | 216 | + hydrolase, hydrolyzing O-glycosyl compounds | ||
cd06602 | GH31_MGAM_SI_GAA | 3.0e-37 | 82 | 165 | 85 | + This family includes the following three closely related glycosyl hydrolase family 31 (GH31) enzymes: maltase-glucoamylase (MGAM), sucrase-isomaltase (SI), and lysosomal acid alpha-glucosidase (GAA), also known as acid-maltase. MGAM is one of the two enzymes responsible for catalyzing the last glucose-releasing step in starch digestion. SI is implicated in the digestion of dietary starch and major disaccharides such as sucrose and isomaltose, while GAA degrades glycogen in the lysosome, cleaving both alpha-1,4 and alpha-1,6 glucosidic linkages. MGAM and SI are anchored to small-intestinal brush-border epithelial cells. The absence of SI from the brush border membrane or its malfunction is associated with malabsorption disorders such as congenital sucrase-isomaltase deficiency (CSID). The domain architectures of MGAM and SI include two tandem GH31 catalytic domains, an N-terminal domain found near the membrane-bound end, and a C-terminal luminal domain. Both of the tandem GH31 domains of MGAM and SI are included in this family. The domain architecture of GAA includes an N-terminal TFF (trefoil factor family) domain in addition to the GH31 catalytic domain. Deficient GAA expression causes pompe disease, an autosomal recessive genetic disorder also known as glycogen storage disease type II (GSDII). | ||
COG1501 | COG1501 | 2.0e-38 | 82 | 312 | 231 | + Alpha-glucosidases, family 31 of glycosyl hydrolases [Carbohydrate transport and metabolism] | ||
pfam01055 | Glyco_hydro_31 | 1.0e-60 | 82 | 236 | 157 | + Glycosyl hydrolases family 31. Glycosyl hydrolases are key enzymes of carbohydrate metabolism. Family 31 comprises of enzymes that are, or similar to, alpha- galactosidases. |
Gene Ontology | |
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GO Term | Description |
GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds |
GO:0005975 | carbohydrate metabolic process |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD05539.1 | 0 | 82 | 396 | 593 | 905 | alpha-xylosidase precursor [Arabidopsis thaliana] |
EMBL | CAA10382.2 | 0 | 82 | 396 | 620 | 934 | alpha-D-xylosidase [Tropaeolum majus] |
RefSeq | XP_002311455.1 | 0 | 82 | 396 | 592 | 907 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002315944.1 | 0 | 82 | 396 | 610 | 925 | predicted protein [Populus trichocarpa] |
RefSeq | XP_002531635.1 | 0 | 82 | 396 | 612 | 927 | alpha-glucosidase, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3w38_A | 0 | 82 | 330 | 606 | 851 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 3w37_A | 0 | 82 | 330 | 606 | 851 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 3top_B | 3e-35 | 84 | 393 | 615 | 902 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 3top_A | 3e-35 | 84 | 393 | 615 | 902 | A Chain A, Pectin Methylesterase Pema From Erwinia Chrysanthemi |
PDB | 3ton_B | 3e-35 | 84 | 393 | 615 | 902 | A Chain A, Crystral Structure Of The C-Terminal Subunit Of Human Maltase- Glucoamylase |
EST Download unfiltered results here | ||||
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Hit | Length | Start | End | EValue |
HO795307 | 315 | 82 | 396 | 0 |
FG231932 | 265 | 82 | 346 | 0 |
EX276068 | 273 | 82 | 354 | 0 |
FY467360 | 265 | 82 | 346 | 0 |
CO080284 | 262 | 82 | 343 | 0 |
Sequence Alignments (This image is cropped. Click for full image.) |
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