| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G05850.1 |
| Family | GH19 |
| Protein Properties | Length: 322 Molecular Weight: 35579.5 Isoelectric Point: 7.6289 |
| Chromosome | Chromosome/Scaffold: 1 Start: 1766503 End: 1768695 |
| Description | CHIT13 - Chitinase family protein precursor, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GH19 | 60 | 304 | 0 |
| ISDYFQVYQFEQLFSKRNTPIAHAVGFWDYQSFITAAALFEPLGFGTTGGKLMGQKEMAAFLGHVASKTSCGYGVATGGPLAWGLCYNREMSPMQSYCDE SWKFKYPCSPGAEYYGRGALPIYWNFNYGAAGEALKADLLNHPEYIEQNATLAFQAAIWRWMTPIKRAQPSAHDIFVGNWKPTKNDTLSKRGPTFGSTMN VLYGEYTCGQGSIDPMNNIISHYLYFLDLMGIGREDAGPNDELSC | |||
| Full Sequence |
|---|
| Protein Sequence Length: 322 Download |
| MVTIRSGSIV ILVLLAVSFL ALVANGEDKT IKVKKVRGNK VCTQGWECSW WSKYCCNQTI 60 SDYFQVYQFE QLFSKRNTPI AHAVGFWDYQ SFITAAALFE PLGFGTTGGK LMGQKEMAAF 120 LGHVASKTSC GYGVATGGPL AWGLCYNREM SPMQSYCDES WKFKYPCSPG AEYYGRGALP 180 IYWNFNYGAA GEALKADLLN HPEYIEQNAT LAFQAAIWRW MTPIKRAQPS AHDIFVGNWK 240 PTKNDTLSKR GPTFGSTMNV LYGEYTCGQG SIDPMNNIIS HYLYFLDLMG IGREDAGPND 300 ELSCAEQKPF NPSTVPSSSS S* 360 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00442 | lysozyme_like | 0.006 | 166 | 234 | 72 | + lysozyme_like domain. This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases. All the members are involved in the hydrolysis of beta-1,4- linked polysaccharides. | ||
| pfam00182 | Glyco_hydro_19 | 4.0e-63 | 68 | 304 | 237 | + Chitinase class I. | ||
| cd00325 | chitinase_glyco_hydro_19 | 2.0e-99 | 64 | 304 | 241 | + Glycoside hydrolase family 19 chitinase domain. Chitinases are enzymes that catalyze the hydrolysis of the beta-1,4-N-acetyl-D-glucosamine linkages in chitin polymers. Family 19 chitinases are found primarily in plants (classes I, III, and IV), but some are found in bacteria. Class I and II chitinases are similar in their catalytic domains. Class I chitinases have an N-terminal cysteine-rich, chitin-binding domain which is separated from the catalytic domain by a proline and glycine-rich hinge region. Class II chitinases lack both the chitin-binding domain and the hinge region. Class IV chitinases are similar to class I chitinases but they are smaller in size due to certain deletions. Despite any significant sequence homology with lysozymes, structural analysis reveals that family 19 chitinases, together with family 46 chitosanases, are similar to several lysozymes including those from T4-phage and from goose. The structures reveal that the different enzyme groups arose from a common ancestor glycohydrolase antecedent to the procaryotic/eucaryotic divergence. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0004568 | chitinase activity |
| GO:0006032 | chitin catabolic process |
| GO:0009408 | response to heat |
| GO:0009414 | response to water deprivation |
| GO:0009651 | response to salt stress |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAP80800.1 | 0 | 1 | 311 | 1 | 314 | class VII chitinase precursor [Gossypium hirsutum] |
| GenBank | ABV89660.1 | 0 | 1 | 311 | 1 | 311 | chitinase [Brassica rapa] |
| DDBJ | BAH30273.1 | 0 | 1 | 316 | 1 | 316 | hypothetical protein [Arabidopsis thaliana] |
| RefSeq | NP_172076.1 | 0 | 1 | 316 | 1 | 316 | POM1 (POM-POM1); chitinase [Arabidopsis thaliana] |
| RefSeq | XP_002515664.1 | 0 | 9 | 321 | 8 | 321 | chitinase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3cql_B | 0 | 69 | 310 | 11 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3cql_A | 0 | 69 | 310 | 11 | 242 | A Chain A, Crystal Structure Of Gh Family 19 Chitinase From Carica Papaya |
| PDB | 3w3e_B | 0 | 69 | 310 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| PDB | 3w3e_A | 0 | 69 | 310 | 12 | 241 | A Chain A, Structure Of Vigna Unguiculata Chitinase With Regulation Activity Of The Plant Cell Wall |
| PDB | 1dxj_A | 0 | 69 | 310 | 11 | 240 | A Chain A, Structure Of The Chitinase From Jack Bean |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| chitin degradation II | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12623 | EC-3.2.1.14 | chitinase |
| chitin degradation II | RXN-12624 | EC-3.2.1.14 | chitinase |
| chitin degradation III (carnivorous plants) | 3.2.1.14-RXN | EC-3.2.1.14 | chitinase |
