| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G07890.2 |
| Family | AA2 |
| Protein Properties | Length: 251 Molecular Weight: 27561.2 Isoelectric Point: 6.0396 |
| Chromosome | Chromosome/Scaffold: 1 Start: 2437437 End: 2439665 |
| Description | OsAPx2 - Cytosolic Ascorbate Peroxidase encoding gene 4,5,6,8, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA2 | 25 | 246 | 0 |
| GLIAEKNCAPIMVRLAWHSAGTFDCQSRTGGPFGTMRFDAEQAHGANSGIHIALRLLDPIREQFPTISFADFHQLAGVVAVEVTGGPDIPFHPGREDKPQ PPPEGRLPDATKGCDHLRDVFAKQMGLSDKDIVALSGAHTLGRCHKDRSGFEGAWTSNPLIFDNSYFKELLSGEKEGLLQLVSDKALLDDPVFRPLVEKY AADEDAFFADYAEAHMKLSELG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 251 Download |
| MTKNYPTVSE DYKKAVEKCR RKLRGLIAEK NCAPIMVRLA WHSAGTFDCQ SRTGGPFGTM 60 RFDAEQAHGA NSGIHIALRL LDPIREQFPT ISFADFHQLA GVVAVEVTGG PDIPFHPGRE 120 DKPQPPPEGR LPDATKGCDH LRDVFAKQMG LSDKDIVALS GAHTLGRCHK DRSGFEGAWT 180 SNPLIFDNSY FKELLSGEKE GLLQLVSDKA LLDDPVFRPL VEKYAADEDA FFADYAEAHM 240 KLSELGFADA * 300 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| cd00314 | plant_peroxidase_like | 9.0e-43 | 23 | 223 | 229 | + Heme-dependent peroxidases similar to plant peroxidases. Along with animal peroxidases, these enzymes belong to a group of peroxidases containing a heme prosthetic group (ferriprotoporphyrin IX), which catalyzes a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. The plant peroxidase-like superfamily is found in all three kingdoms of life and carries out a variety of biosynthetic and degradative functions. Several sub-families can be identified. Class I includes intracellular peroxidases present in fungi, plants, archaea and bacteria, called catalase-peroxidases, that can exhibit both catalase and broad-spectrum peroxidase activities depending on the steady-state concentration of hydrogen peroxide. Catalase-peroxidases are typically comprised of two homologous domains that probably arose via a single gene duplication event. Class II includes ligninase and other extracellular fungal peroxidases, while class III is comprised of classic extracellular plant peroxidases, like horseradish peroxidase. | ||
| PLN02608 | PLN02608 | 2.0e-116 | 6 | 247 | 242 | + L-ascorbate peroxidase | ||
| PLN02879 | PLN02879 | 7.0e-123 | 1 | 249 | 249 | + L-ascorbate peroxidase | ||
| cd00691 | ascorbate_peroxidase | 8.0e-131 | 5 | 250 | 254 | + Ascorbate peroxidases and cytochrome C peroxidases. Ascorbate peroxidases are a subgroup of heme-dependent peroxidases of the plant superfamily that share a heme prosthetic group and catalyze a multistep oxidative reaction involving hydrogen peroxide as the electron acceptor. Along with related catalase-peroxidases, ascorbate peroxidases belong to class I of the plant superfamily. Ascorbate peroxidases are found in the chloroplasts and/or cytosol of algae and plants, where they have been shown to control the concentration of lethal hydrogen peroxide molecules. The yeast cytochrome c peroxidase is a divergent member of the family; it forms a complex with cytochrome c to catalyze the reduction of hydrogen peroxide to water. | ||
| PLN02364 | PLN02364 | 1.0e-159 | 1 | 250 | 250 | + L-ascorbate peroxidase 1 | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0000302 | response to reactive oxygen species |
| GO:0004601 | peroxidase activity |
| GO:0005618 | cell wall |
| GO:0005829 | cytosol |
| GO:0005886 | plasma membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAN60794.1 | 0 | 1 | 250 | 1 | 250 | ascorbate peroxidase [Brassica juncea] |
| GenBank | AAN60795.1 | 0 | 1 | 250 | 1 | 250 | ascorbate peroxidase [Brassica juncea] |
| DDBJ | BAB84009.1 | 0 | 1 | 250 | 1 | 250 | ascorbate peroxidase [Brassica oleracea] |
| RefSeq | NP_001077481.1 | 0 | 1 | 247 | 1 | 247 | APX1 (ascorbate peroxidase 1); L-ascorbate peroxidase [Arabidopsis thaliana] |
| RefSeq | NP_172267.1 | 0 | 1 | 250 | 1 | 250 | APX1 (ascorbate peroxidase 1); L-ascorbate peroxidase [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1apx_D | 0 | 3 | 250 | 2 | 249 | A Chain A, Crystal Structure Of Recombinant Ascorbate Peroxidase |
| PDB | 1apx_C | 0 | 3 | 250 | 2 | 249 | A Chain A, Crystal Structure Of Recombinant Ascorbate Peroxidase |
| PDB | 1apx_B | 0 | 3 | 250 | 2 | 249 | A Chain A, Crystal Structure Of Recombinant Ascorbate Peroxidase |
| PDB | 1apx_A | 0 | 3 | 250 | 2 | 249 | A Chain A, Crystal Structure Of Recombinant Ascorbate Peroxidase |
| PDB | 2xj6_A | 0 | 3 | 250 | 2 | 249 | A Chain A, Crystal Structure Of Recombinant Ascorbate Peroxidase |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| ascorbate glutathione cycle | RXN-3521 | - | L-ascorbate peroxidase |
| L-ascorbate degradation III | RXN-12440 | EC-1.11.1.11 | L-ascorbate peroxidase |
| L-ascorbate degradation V | RXN-12440 | EC-1.11.1.11 | L-ascorbate peroxidase |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| EG494540 | 251 | 1 | 251 | 0 |
| CF651760 | 251 | 1 | 251 | 0 |
| CF652474 | 251 | 1 | 251 | 0 |
| DY902145 | 251 | 1 | 251 | 0 |
| JZ151642 | 251 | 1 | 251 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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