| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G16980.1 |
| Family | GT20 |
| Protein Properties | Length: 822 Molecular Weight: 92873.7 Isoelectric Point: 5.7406 |
| Chromosome | Chromosome/Scaffold: 1 Start: 5807311 End: 5811488 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 10 | 477 | 0 |
| RPRLLVVANRLPVSAKRTGENSWSLEMSPGGLVSGLLGITSQFDTKWVGWPGVDVHDEIEKNALTESLAEMKCIPVFLNGVFDQYYNGYCNGILWPILHH MGLPQEDQHDTNQTFETQYDAYKKANRMFLDVIIDNYEEGDIVWCHDYHLMFLPQYLKEYNNKIKVGWFLHSPFPSSEVYKTLPSRSELLRAILAADLLG FHTYDFARHFLSTCTRILGVEGTHEGVVYQGRVTRVAVFPIGIDPDRFIRTCKLPEVTQQMNELQEKFAGKKVILGVDRLDMIKGIPQKYLAFEKFLEEN PYWRDKVVLVQIAVPTRNDVPEYRKLKSQVHGLVGRINGRFGSVSSLPIHHLDCSVDFNYLCAIYAIADVMLVTSLRDGMNLVSYEFVACQEAKKGVLVL SEFAGAGQSLGVGALIVNPWDVTEVSSAIKEALNMPAEERETRHRSNFQYVCTHSAEKWGLDFMSELN | |||
| Full Sequence |
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| Protein Sequence Length: 822 Download |
| MDYDDARGER PRLLVVANRL PVSAKRTGEN SWSLEMSPGG LVSGLLGITS QFDTKWVGWP 60 GVDVHDEIEK NALTESLAEM KCIPVFLNGV FDQYYNGYCN GILWPILHHM GLPQEDQHDT 120 NQTFETQYDA YKKANRMFLD VIIDNYEEGD IVWCHDYHLM FLPQYLKEYN NKIKVGWFLH 180 SPFPSSEVYK TLPSRSELLR AILAADLLGF HTYDFARHFL STCTRILGVE GTHEGVVYQG 240 RVTRVAVFPI GIDPDRFIRT CKLPEVTQQM NELQEKFAGK KVILGVDRLD MIKGIPQKYL 300 AFEKFLEENP YWRDKVVLVQ IAVPTRNDVP EYRKLKSQVH GLVGRINGRF GSVSSLPIHH 360 LDCSVDFNYL CAIYAIADVM LVTSLRDGMN LVSYEFVACQ EAKKGVLVLS EFAGAGQSLG 420 VGALIVNPWD VTEVSSAIKE ALNMPAEERE TRHRSNFQYV CTHSAEKWGL DFMSELNGII 480 PESEMQMRKI PLQLPEQDVI QQYSQSNNRL IILGFFGTLA EPMNSGTKEM DLKLNPELKG 540 TLKALCNDPK TTVVVLSRSG KNILNKNFGE SNIWLAAENG MFEKQTTGEW VTNMPQNVNL 600 DWVDGVKNVF KYFTDRTPRS YFEASETSLV WNYEYADVEF GRAQARDLLQ YLWAGPISNA 660 SVDVVRGNHS VEVHAIGETK GAAIGRILGE IVHRKSMTTP IDFVFCSGYF LEKDEDIYTF 720 FESKILSSKS PNGLDLKKEN YFSAAIGQAR TKARYVIDSA HGVVDLLHKL AVVADTTMTD 780 SFSDSEIYEP RDANANENSK RWINSVRRRK VEIGDTGQIG M* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 1.0e-6 | 730 | 777 | 48 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 1 | 785 | 799 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03064 | PLN03064 | 0 | 4 | 732 | 736 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 0 | 12 | 771 | 768 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 12 | 477 | 468 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| GO:0005575 | cellular_component |
| GO:0005992 | trehalose biosynthetic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50035.1 | 0 | 56 | 779 | 3 | 693 | AC007651_30 Very similar to trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_173142.1 | 0 | 1 | 821 | 1 | 821 | ATTPS2; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_173143.4 | 0 | 1 | 779 | 1 | 777 | ATTPS3; alpha,alpha-trehalose-phosphate synthase (UDP-forming) [Arabidopsis thaliana] |
| Swiss-Prot | Q9FZ57 | 0 | 1 | 821 | 2 | 822 | TPS2_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2; AltName: Full=Trehalose-6-phosphate synthase 2; Short=AtTPS2 |
| Swiss-Prot | Q9SHG0 | 0 | 1 | 779 | 1 | 724 | TPS3_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 3; AltName: Full=Trehalose-6-phosphate synthase 3; Short=AtTPS3 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 12 | 488 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 12 | 488 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 12 | 488 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 12 | 488 | 3 | 464 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1uqu_B | 0 | 12 | 488 | 3 | 464 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| DW069910 | 288 | 98 | 385 | 0 |
| ES813375 | 361 | 373 | 727 | 0 |
| CV711307 | 294 | 10 | 302 | 0 |
| ES332740 | 306 | 126 | 430 | 0 |
| CX546763 | 293 | 10 | 301 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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