| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G17000.1 |
| Family | GT20 |
| Protein Properties | Length: 784 Molecular Weight: 89474.1 Isoelectric Point: 7.6667 |
| Chromosome | Chromosome/Scaffold: 1 Start: 5812728 End: 5816660 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 12 | 455 | 0 |
| TLLVVANRLPASAKRTGEHSWSLEMSPGGKFNLLVEKDAVSKSLAEMKCIPVFLNEVFDQYYNGYSNGILWPILHHMGLPQEYDHDTIKTFETQYDAYKK ANRMFLDVIKENYKDGDIVWCQDYHLMFLPQYLKEYNNKIKVGWFLHSPFPSSEIYKTLPSRSELLRSVLAADLISFHTYDFARHFVNTCTRILGVEGTH EGVVYQGRVTRVVVLPMGIYPNRFIKTCKLPEVIQQMNELKDRFSGKKVILGVDRLDMIKGIPQKYLGFEKFLDENPNWRDKIVLVQIAVPTRNEVPEYQ KLKNQVHRLVGRINGRFGSVSSLPIHHMDCSVDSNYLCALYAISDVMLVTSLRDGLNLVSHEFVACQEAKRGVLILSEFAGAGQSLGAGALLVNPWNVTE VSSAIKKALNMPYEERETRHRVNFKYVKTHSAEKWGFDFLSELN | |||
| Full Sequence |
|---|
| Protein Sequence Length: 784 Download |
| MGYDNVCGER QTLLVVANRL PASAKRTGEH SWSLEMSPGG KFNLLVEKDA VSKSLAEMKC 60 IPVFLNEVFD QYYNGYSNGI LWPILHHMGL PQEYDHDTIK TFETQYDAYK KANRMFLDVI 120 KENYKDGDIV WCQDYHLMFL PQYLKEYNNK IKVGWFLHSP FPSSEIYKTL PSRSELLRSV 180 LAADLISFHT YDFARHFVNT CTRILGVEGT HEGVVYQGRV TRVVVLPMGI YPNRFIKTCK 240 LPEVIQQMNE LKDRFSGKKV ILGVDRLDMI KGIPQKYLGF EKFLDENPNW RDKIVLVQIA 300 VPTRNEVPEY QKLKNQVHRL VGRINGRFGS VSSLPIHHMD CSVDSNYLCA LYAISDVMLV 360 TSLRDGLNLV SHEFVACQEA KRGVLILSEF AGAGQSLGAG ALLVNPWNVT EVSSAIKKAL 420 NMPYEERETR HRVNFKYVKT HSAEKWGFDF LSELNDAFDE SELQIRKIPH ELPQQDVIQR 480 YSLSNNRLII LGFYGTITEP RNSLSKEMDL XLNPELKETL KALCNDPKTT VVVLSRSGKN 540 ILDKNFGEYK IWLAAENGMF LKHTTEEWVT NMPQNMNLDW VDGLKNVFKY FTDRTPRSFF 600 EASKTSLVWN YEYADVEFGR AQARDLLQYL WAGPISNASA EVVRGKYSVE VHAIGVTKEP 660 EIGHILGEIV HKKAMTTPID YVFCSGYFLE KDEDIYTFFE SEILSPKLSH ETRSKSSSSN 720 HSLEKKVSLN VLDLKQENYF STAIGQARTK ARYVVDSSHN VVNLLHKLAV ANTTTTSVKK 780 PNV* 840 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03064 | PLN03064 | 3.0e-9 | 730 | 775 | 46 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03063 | PLN03063 | 0 | 1 | 783 | 804 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN03064 | PLN03064 | 0 | 10 | 703 | 722 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PRK14501 | PRK14501 | 0 | 13 | 686 | 706 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 13 | 455 | 467 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| GO:0005575 | cellular_component |
| GO:0005992 | trehalose biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50035.1 | 0 | 38 | 783 | 7 | 699 | AC007651_30 Very similar to trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| RefSeq | NP_173142.1 | 0 | 1 | 777 | 1 | 779 | ATTPS2; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups [Arabidopsis thaliana] |
| RefSeq | NP_173143.4 | 0 | 1 | 783 | 1 | 783 | ATTPS3; alpha,alpha-trehalose-phosphate synthase (UDP-forming) [Arabidopsis thaliana] |
| Swiss-Prot | Q9FZ57 | 0 | 1 | 777 | 2 | 780 | TPS2_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 2; AltName: Full=Trehalose-6-phosphate synthase 2; Short=AtTPS2 |
| Swiss-Prot | Q9SHG0 | 0 | 1 | 783 | 1 | 730 | TPS3_ARATH RecName: Full=Probable alpha,alpha-trehalose-phosphate synthase [UDP-forming] 3; AltName: Full=Trehalose-6-phosphate synthase 3; Short=AtTPS3 |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 69 | 454 | 73 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 69 | 454 | 73 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 69 | 454 | 73 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 69 | 454 | 73 | 451 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 69 | 454 | 72 | 450 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| ES813375 | 361 | 351 | 705 | 0 |
| DW069910 | 288 | 76 | 363 | 0 |
| CX545499 | 305 | 293 | 591 | 0 |
| ES332740 | 316 | 104 | 418 | 0 |
| DT601611 | 256 | 108 | 363 | 0 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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