| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G23870.1 |
| Family | GT20 |
| Protein Properties | Length: 868 Molecular Weight: 98495.8 Isoelectric Point: 6.3002 |
| Chromosome | Chromosome/Scaffold: 1 Start: 8432179 End: 8435656 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 53 | 546 | 0 |
| SSNSSRERKIIVANMLPLQAKRDTETGQWCFSWDEDSLLLQLRDGFSSDTEFVYIGSLNADIGISEQEEVSHKLLLDFNCVPTFLPKEMQEKFYLGFCKH HLWPLFHYMLPMFPDHGDRFDRRLWQAYVSANKIFSDRVMEVINPEEDYVWIHDYHLMVLPTFLRKRFNRIKLGFFLHSPFPSSEIYRTLPVRDDLLRGL LNCDLIGFHTFDYARHFLSCCSRMLGLDYESKRGHIGLDYFGRTVFIKILPVGIHMGRLESVLNLPSTAAKMKEIQEQFKGKKLILGVDDMDIFKGISLK LIAMERLFETYWHMRGKLVLIQIVNPARATGKDVEEAKKETYSTAKRINERYGSAGYQPVILIDRLVPRYEKTAYYAMADCCLVNAVRDGMNLVPYKYII CRQGTPGMDKAMGISHDSARTSMLVVSEFIGCSPSLSGAIRVNPWDVDAVAEAVNLALTMGETEKRLRHEKHYHYVSTHDVGYWAKSFMQDLER | |||
| Full Sequence |
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| Protein Sequence Length: 868 Download |
| MVSRSCANFL DLASWDLLDF PQTQRALPRV MTVPGIISEL DGGYSDGSSD VNSSNSSRER 60 KIIVANMLPL QAKRDTETGQ WCFSWDEDSL LLQLRDGFSS DTEFVYIGSL NADIGISEQE 120 EVSHKLLLDF NCVPTFLPKE MQEKFYLGFC KHHLWPLFHY MLPMFPDHGD RFDRRLWQAY 180 VSANKIFSDR VMEVINPEED YVWIHDYHLM VLPTFLRKRF NRIKLGFFLH SPFPSSEIYR 240 TLPVRDDLLR GLLNCDLIGF HTFDYARHFL SCCSRMLGLD YESKRGHIGL DYFGRTVFIK 300 ILPVGIHMGR LESVLNLPST AAKMKEIQEQ FKGKKLILGV DDMDIFKGIS LKLIAMERLF 360 ETYWHMRGKL VLIQIVNPAR ATGKDVEEAK KETYSTAKRI NERYGSAGYQ PVILIDRLVP 420 RYEKTAYYAM ADCCLVNAVR DGMNLVPYKY IICRQGTPGM DKAMGISHDS ARTSMLVVSE 480 FIGCSPSLSG AIRVNPWDVD AVAEAVNLAL TMGETEKRLR HEKHYHYVST HDVGYWAKSF 540 MQDLERACRE HYNKRCWGIG FGLSFRVLSL SPSFRKLSID HIVSTYRNTQ RRAIFLDYDG 600 TLVPESSIIK TPNAEVLSVL KSLCGDPKNT VFVVSGRGWE SLSDWLSPCE NLGIAAEHGY 660 FIRWSSKKEW ETCYSSAEAE WKTMVEPVMR SYMDATDGST IEYKESALVW HHQDADPDFG 720 ACQAKELLDH LESVLANEPV VVKRGQHIVE VKPQGVSKGL AVEKVIHQMV EDGNPPDMVM 780 CIGDDRSDED MFESILSTVT NPDLPMPPEI FACTVGRKPS KAKYFLDDVS DVLKLLGGLA 840 AATSSSKPEY QQQSSSLHTQ VAFESII* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 1.0e-172 | 58 | 849 | 834 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 849 | 854 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 59 | 546 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 60 | 842 | 790 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 62 | 545 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0004805 | trehalose-phosphatase activity |
| GO:0005992 | trehalose biosynthetic process |
| GO:0008152 | metabolic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAC18810.1 | 0 | 31 | 867 | 1 | 826 | Strong similarity to trehalose-6-phosphate synthase homolog from A. thaliana chromosome 4 contig gb |
| GenBank | AAV65494.1 | 0 | 1 | 865 | 1 | 859 | trehalose 6-phosphate synthase [Gossypium hirsutum] |
| RefSeq | NP_173799.1 | 0 | 1 | 867 | 1 | 867 | ATTPS9; transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | NP_177186.2 | 0 | 1 | 867 | 1 | 856 | ATTPS8; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002521023.1 | 0 | 1 | 867 | 1 | 861 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 143 | 546 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 143 | 546 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 143 | 546 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 143 | 546 | 74 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 143 | 546 | 73 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 767 | 81 | 843 | 0 |
| HO779327 | 514 | 99 | 612 | 0 |
| HO779327 | 259 | 610 | 868 | 0 |
| HO797286 | 481 | 377 | 855 | 0 |
| HO777775 | 78 | 1 | 77 | 0.01 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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