| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G26390.1 |
| Family | AA7 |
| Protein Properties | Length: 531 Molecular Weight: 58947.8 Isoelectric Point: 9.5274 |
| Chromosome | Chromosome/Scaffold: 1 Start: 9130017 End: 9131779 |
| Description | berberine and berberine like domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 75 | 524 | 0 |
| RKLLAIVAAKHVSHVQATVVCAKSNGIQLRIRSGGHDYEGLSYMSSVPFVILDMYNLRSITVDVSSKKAWIQAGATLGELYTNVNDVSQTLAFPAGVCAT VGAGGHISGGGYGNLMRKYGITVDHVIDAQIIDVNGKLLNRATMGEDLFWAIRGGGGGSFGVILSWKINLVDVPKIVTVFKVNKTLEQGGTDVLYKWQLV ASKFPESLFVRAMPQVANGTKRGERTITVVFYAQFLGRTDALMAIMNQNWPELGLKHEDCQEMSWLNSTLFWADYPAGTPTSILLDRPSSPGDFFKSKSD YVKKPIPKEGLEKLWKTMLKFNNNIVWMQFNPYGGVMDRIPATATAFPHRKGNLFKIQYFTTWFNANATMSSLSQMKELYEVAEPYVSSNPREAFFNYRD IDVGSNPSGETNVDEAKIYGSKYFLGNLKRLMDVKAKYDPDNFFKNEQSI | |||
| Full Sequence |
|---|
| Protein Sequence Length: 531 Download |
| MKGTLSVLCL VLLVSVLEAA VTKPKFGDFI GCLRYRTSPE NPITDAISFA DNTTTFLSSY 60 VSYTKNKRFS TPNYRKLLAI VAAKHVSHVQ ATVVCAKSNG IQLRIRSGGH DYEGLSYMSS 120 VPFVILDMYN LRSITVDVSS KKAWIQAGAT LGELYTNVND VSQTLAFPAG VCATVGAGGH 180 ISGGGYGNLM RKYGITVDHV IDAQIIDVNG KLLNRATMGE DLFWAIRGGG GGSFGVILSW 240 KINLVDVPKI VTVFKVNKTL EQGGTDVLYK WQLVASKFPE SLFVRAMPQV ANGTKRGERT 300 ITVVFYAQFL GRTDALMAIM NQNWPELGLK HEDCQEMSWL NSTLFWADYP AGTPTSILLD 360 RPSSPGDFFK SKSDYVKKPI PKEGLEKLWK TMLKFNNNIV WMQFNPYGGV MDRIPATATA 420 FPHRKGNLFK IQYFTTWFNA NATMSSLSQM KELYEVAEPY VSSNPREAFF NYRDIDVGSN 480 PSGETNVDEA KIYGSKYFLG NLKRLMDVKA KYDPDNFFKN EQSIPPVRVM * 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 2.0e-13 | 78 | 527 | 475 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 2.0e-14 | 468 | 525 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam01565 | FAD_binding_4 | 2.0e-19 | 78 | 214 | 138 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0009055 | electron carrier activity |
| GO:0012505 | endomembrane system |
| GO:0016491 | oxidoreductase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK93677.1 | 0 | 1 | 530 | 1 | 530 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_173964.1 | 0 | 1 | 530 | 1 | 527 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_173966.1 | 0 | 1 | 530 | 1 | 528 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564244.1 | 0 | 1 | 527 | 1 | 525 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564245.1 | 0 | 1 | 530 | 1 | 530 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3tsj_B | 0 | 28 | 527 | 10 | 496 | B Chain B, Reassembly And Co-Crystallization Of A Family 9 Processive Endoglucanase From Separately Expressed Gh9 And Cbm3c Modules |
| PDB | 3tsj_A | 0 | 28 | 527 | 10 | 496 | B Chain B, Reassembly And Co-Crystallization Of A Family 9 Processive Endoglucanase From Separately Expressed Gh9 And Cbm3c Modules |
| PDB | 3tsh_A | 0 | 28 | 527 | 10 | 496 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
| PDB | 3vte_A | 0 | 28 | 527 | 6 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 4dns_B | 0 | 28 | 527 | 12 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
