| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G26420.1 |
| Family | AA7 |
| Protein Properties | Length: 530 Molecular Weight: 59217.3 Isoelectric Point: 9.6174 |
| Chromosome | Chromosome/Scaffold: 1 Start: 9141567 End: 9143304 |
| Description | reticuline oxidase-like protein precursor, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| AA7 | 78 | 286 | 0 |
| LAIVAAKHVSHVQATVVCAKTNGIQLRIRSGGHDLEGLSYRSSVPFVILDMFNLRSITVNVLSKKAWVQAGATLGELYVKINEASQTLAFPAGVCPTVGV GGHISGGGYGNLMRKFGITVDHVSDAQLIDVNGKLLNRASMGEDLFWAIRGGGGASFGVILSWKINLVKVPKILTVFKVNKTLEQGGTDVLYKWQLVATK FPEDLFMRA | |||
| Full Sequence |
|---|
| Protein Sequence Length: 530 Download |
| MKEALSILCL ALLVSVSEAE VTKPNSENFI ECLRYRTSSE NPITDSISIA DNTTTFLSSY 60 LSYTKNKRYS SPNFKKLLAI VAAKHVSHVQ ATVVCAKTNG IQLRIRSGGH DLEGLSYRSS 120 VPFVILDMFN LRSITVNVLS KKAWVQAGAT LGELYVKINE ASQTLAFPAG VCPTVGVGGH 180 ISGGGYGNLM RKFGITVDHV SDAQLIDVNG KLLNRASMGE DLFWAIRGGG GASFGVILSW 240 KINLVKVPKI LTVFKVNKTL EQGGTDVLYK WQLVATKFPE DLFMRAWPQI INGAERGDRT 300 IAVVFYAQFL GPADKLLAIM NQRLPELGLR REDCHEMSWF NTTLFWADYP AGTPKSVLLD 360 RPTNPGFFKS KSDYVKKPIP KEGLEKLWKT MFKFNNIVWM QFNPYGGVMD QIPSTATAFP 420 HRKGNMFKVQ YSTTWLAANA TEISLSMMKE LYKVAEPYVS SNPREAFFNY RDIDIGSNPS 480 DETNVDEAKI YGYKYFLGNL KRLMQVKAKY DPENFFKNEQ SIPPVRVIE* 540 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0277 | GlcD | 2.0e-13 | 78 | 249 | 180 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
| pfam08031 | BBE | 5.0e-15 | 466 | 523 | 58 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
| pfam01565 | FAD_binding_4 | 2.0e-19 | 78 | 214 | 138 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
| GO:0009055 | electron carrier activity |
| GO:0012505 | endomembrane system |
| GO:0016491 | oxidoreductase activity |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAK93677.1 | 0 | 18 | 528 | 18 | 530 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_173965.1 | 0 | 2 | 527 | 26 | 551 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_173966.1 | 0 | 1 | 529 | 1 | 529 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564244.1 | 0 | 1 | 525 | 1 | 525 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| RefSeq | NP_564245.1 | 0 | 18 | 528 | 18 | 530 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3vte_A | 0 | 27 | 525 | 5 | 513 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_B | 0 | 27 | 525 | 9 | 496 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsj_A | 0 | 27 | 525 | 9 | 496 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
| PDB | 3tsh_A | 0 | 27 | 525 | 9 | 496 | A Chain A, Crystal Structure Of Phl P 4, A Grass Pollen Allergen With Glucose Dehydrogenase Activity |
| PDB | 4dns_B | 0 | 50 | 525 | 28 | 496 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |
