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Basic Information | |
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Species | Arabidopsis thaliana |
Cazyme ID | AT1G30760.1 |
Family | AA7 |
Protein Properties | Length: 535 Molecular Weight: 60192.1 Isoelectric Point: 6.368 |
Chromosome | Chromosome/Scaffold: 1 Start: 10918278 End: 10920677 |
Description | reticuline oxidase-like protein precursor, putative, expressed |
View CDS |
Signature Domain Download full data set without filtering | |||
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Family | Start | End | Evalue |
AA7 | 73 | 308 | 0 |
NLRYLMPSNPKPEFIFEPLYETHVQAAVLCAKKLKLHLRLRSGGHDYEGLSYVSEMETAFVIVDLSKLRQISVDIESNSAWVHAGASIGEVYYRIQEKSK IHGFPAGLCTSLGIGGHIIGGAYGSMMRKFGLGADNVLDARIVDADGKILNRAAMGEDVFWAIRGGGGGSFGVILAWKIKLVPVPEIVTVFTVTRTLEQD GTKLLYKWQQVADKLDEDLFIRVIIQPTSKTPKSKE |
Full Sequence |
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Protein Sequence Length: 535 Download |
MAFVLMNNTN AFLVTLLLLS LSYIPLSFST IQQDFVMCLV DNSDASFPMD SSFFTHDLNA 60 SSFKLALETS AQNLRYLMPS NPKPEFIFEP LYETHVQAAV LCAKKLKLHL RLRSGGHDYE 120 GLSYVSEMET AFVIVDLSKL RQISVDIESN SAWVHAGASI GEVYYRIQEK SKIHGFPAGL 180 CTSLGIGGHI IGGAYGSMMR KFGLGADNVL DARIVDADGK ILNRAAMGED VFWAIRGGGG 240 GSFGVILAWK IKLVPVPEIV TVFTVTRTLE QDGTKLLYKW QQVADKLDED LFIRVIIQPT 300 SKTPKSKERT ISTSYQGQFL GDANRLLQVM QRSFPQLGLT KKDCLETSWI KSVMYIAGFP 360 STAPSEALLD GKSLFKNYFK AKSDYVEEPI PVEGLEGLWE KLLEEDSPLT IWNPYGGMMA 420 KIPETETPFP HRSGTLFKIQ WLTLWQDGKT SEAKHMGWMR EMYSYMEQYV SKSPRSAYVN 480 YRDLDLGMNG KGSDAREWGN RYFKGNFERL VEIKAKFDPE NFFRHEQSIP TELE* 540 |
Functional Domains Download unfiltered results here | ||||||||
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Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
TIGR01678 | FAD_lactone_ox | 0.001 | 83 | 299 | 221 | + sugar 1,4-lactone oxidases. This model represents a family of at least two different sugar 1,4 lactone oxidases, both involved in synthesizing ascorbic acid or a derivative. These include L-gulonolactone oxidase (EC 1.1.3.8) from rat and D-arabinono-1,4-lactone oxidase (EC 1.1.3.37) from Saccharomyces cerevisiae. Members are proposed to have the cofactor FAD covalently bound at a site specified by Prosite motif PS00862; OX2_COVAL_FAD; 1. | ||
COG0277 | GlcD | 2.0e-20 | 96 | 532 | 453 | + FAD/FMN-containing dehydrogenases [Energy production and conversion] | ||
pfam08031 | BBE | 4.0e-21 | 477 | 530 | 54 | + Berberine and berberine like. This domain is found in the berberine bridge and berberine bridge- like enzymes which are involved in the biosynthesis of numerous isoquinoline alkaloids. They catalyze the transformation of the N-methyl group of (S)-reticuline into the C-8 berberine bridge carbon of (S)-scoulerine. | ||
pfam01565 | FAD_binding_4 | 1.0e-21 | 84 | 223 | 141 | + FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidises the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan. |
Gene Ontology | |
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GO Term | Description |
GO:0003824 | catalytic activity |
GO:0008762 | UDP-N-acetylmuramate dehydrogenase activity |
GO:0009055 | electron carrier activity |
GO:0012505 | endomembrane system |
GO:0016491 | oxidoreductase activity |
Annotations - NR Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
GenBank | AAD25763.1 | 0 | 1 | 431 | 1 | 431 | AC007060_21 Strong similarity to F19I3.2 gi |
RefSeq | NP_174363.1 | 0 | 1 | 534 | 1 | 534 | FAD-binding domain-containing protein [Arabidopsis thaliana] |
RefSeq | NP_181025.1 | 0 | 1 | 533 | 1 | 531 | MEE23 (MATERNAL EFFECT EMBRYO ARREST 23); FAD binding / catalytic/ electron carrier/ oxidoreductase [Arabidopsis thaliana] |
RefSeq | XP_002523162.1 | 0 | 31 | 530 | 29 | 529 | Reticuline oxidase precursor, putative [Ricinus communis] |
RefSeq | XP_002523164.1 | 0 | 31 | 530 | 29 | 529 | Reticuline oxidase precursor, putative [Ricinus communis] |
Annotations - PDB Download unfiltered results here | |||||||
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Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
PDB | 3vte_A | 0 | 67 | 530 | 37 | 511 | A Chain A, Crystal Structure Of Tetrahydrocannabinolic Acid Synthase From Cannabis Sativa |
PDB | 4dns_B | 0 | 31 | 533 | 9 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 4dns_A | 0 | 31 | 533 | 9 | 497 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_B | 0 | 32 | 530 | 8 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
PDB | 3tsj_A | 0 | 32 | 530 | 8 | 494 | A Chain A, Crystal Structure Of Bermuda Grass Isoallergen Bg60 Provides Insight Into The Various Cross-Allergenicity Of The Pollen Group 4 Allergens |
Metabolic Pathways | |||
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Pathway Name | Reaction | EC | Protein Name |
cannabinoid biosynthesis | RXN-7854 | EC-1.21.3 | tetrahydrocannabinolic acid synthase |