| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G34270.1 |
| Family | GT47 |
| Protein Properties | Length: 478 Molecular Weight: 53885.6 Isoelectric Point: 9.0785 |
| Chromosome | Chromosome/Scaffold: 1 Start: 12492411 End: 12494544 |
| Description | exostosin family domain containing protein, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT47 | 55 | 395 | 0 |
| NGINVYVAELPRSLNYGLIDKYWSSSTPDSRIPSDPDHPTRKTHSPDKYPPYPENPLIKQYSAEYWIMGDLETSPEKRIGSFAKRVFSESDADVVFVPFF ATLSAEMELGNGKGSFRKKSGNEDYQRQRQVLDFVKNTKAWKRSNGRDHVFVLTDPVAMWHVREEIALSILLVVDFGGWFRQDSKSSNGTSLPERIQHTQ VSVIKDVIVPYTHLLPRLDLSQNQRRHSLLYFKGAKHRHRGGLIREKLWDLLVNEPGVVMEEGFPNATGREQSIRGMRNSEFCLHPAGDTPTSCRLFDAI QSLCIPVIVSDTIELPFEGIIDYSEFSVFASVSDALTPKWL | |||
| Full Sequence |
|---|
| Protein Sequence Length: 478 Download |
| MVPKIASMAS TRPLCSIPSI FLSFSLLFVV SLLFFFSNSL ISNPNPSISH NTLQNGINVY 60 VAELPRSLNY GLIDKYWSSS TPDSRIPSDP DHPTRKTHSP DKYPPYPENP LIKQYSAEYW 120 IMGDLETSPE KRIGSFAKRV FSESDADVVF VPFFATLSAE MELGNGKGSF RKKSGNEDYQ 180 RQRQVLDFVK NTKAWKRSNG RDHVFVLTDP VAMWHVREEI ALSILLVVDF GGWFRQDSKS 240 SNGTSLPERI QHTQVSVIKD VIVPYTHLLP RLDLSQNQRR HSLLYFKGAK HRHRGGLIRE 300 KLWDLLVNEP GVVMEEGFPN ATGREQSIRG MRNSEFCLHP AGDTPTSCRL FDAIQSLCIP 360 VIVSDTIELP FEGIIDYSEF SVFASVSDAL TPKWLANHLG RFSEREKETL RSRIAKVQSV 420 FVYDNGHADG IGPIEPNGAV NHIWKKVQQK VPMVKEAVIR ERRKPAGASV PLRCQCI* 480 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam03016 | Exostosin | 6.0e-57 | 53 | 389 | 349 | + Exostosin family. The EXT family is a family of tumour suppressor genes. Mutations of EXT1 on 8q24.1, EXT2 on 11p11-13, and EXT3 on 19p have been associated with the autosomal dominant disorder known as hereditary multiple exostoses (HME). This is the most common known skeletal dysplasia. The chromosomal locations of other EXT genes suggest association with other forms of neoplasia. EXT1 and EXT2 have both been shown to encode a heparan sulphate polymerase with both D-glucuronyl (GlcA) and N-acetyl-D-glucosaminoglycan (GlcNAC) transferase activities. The nature of the defect in heparan sulphate biosynthesis in HME is unclear. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0008150 | biological_process |
| GO:0012505 | endomembrane system |
| GO:0016020 | membrane |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| RefSeq | NP_564443.1 | 0 | 1 | 477 | 1 | 477 | exostosin family protein [Arabidopsis thaliana] |
| RefSeq | XP_002270238.1 | 0 | 1 | 476 | 1 | 439 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002325567.1 | 0 | 15 | 476 | 13 | 475 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002327326.1 | 0 | 33 | 476 | 5 | 448 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002533317.1 | 0 | 41 | 476 | 39 | 477 | catalytic, putative [Ricinus communis] |
