| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G43620.1 |
| Family | GT1 |
| Protein Properties | Length: 616 Molecular Weight: 68344.8 Isoelectric Point: 5.4702 |
| Chromosome | Chromosome/Scaffold: 1 Start: 16425412 End: 16430200 |
| Description | sterol 3-beta-glucosyltransferase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT1 | 163 | 573 | 0 |
| VGTRGDVQPFLAMAKRLQEFGHRVRLATHANFRSFVRAAGVEFYPLGGDPRELAAYMARNKGLIPSGPSEISKQRKQLKAIIESLLPACIEPDLETATSF RAQAIIANPPAYGHVHVAEALGVPIHIFFTMPWTPTNEFPHPLARVPQSAAYWLSYIVVDLMVWWSIRTYINDFRKRKLNLAPIAYFSTYHGSISHLPTG YMWSPHVVPKPSDWGPLVDVVGYCFLNLGSKYQPREEFLHWIERGSPPVYIGFGSMPLDDPKQTMDIILETLKDTEQRGIVDRGWGGLGNLATEVPENVF LVEDCPHDWLFPQCSAVVHHGGAGTTATGLKAGCPTTIVPFFGDQFFWGDRIYEKGLGPAPIPIAQLSVENLSSSIRFMLQPEVKSQVMELAKVLENEDG VAAAVDAFHRH | |||
| Full Sequence |
|---|
| Protein Sequence Length: 616 Download |
| MASNVFDHPL QELEGEDNGV KSEKASLLET SGSVDTTPED SGHRSSDGHR GLDHCETAPV 60 GLYGDMLIND SEIQYSRSLT EKGSPAIHNL KLDRLSEQEK QKLIVELVRI QNDGTVEVID 120 NGTPVSELWE FEPTKGQSTI TYEKSLTESF RSIPRLKIAI LVVGTRGDVQ PFLAMAKRLQ 180 EFGHRVRLAT HANFRSFVRA AGVEFYPLGG DPRELAAYMA RNKGLIPSGP SEISKQRKQL 240 KAIIESLLPA CIEPDLETAT SFRAQAIIAN PPAYGHVHVA EALGVPIHIF FTMPWTPTNE 300 FPHPLARVPQ SAAYWLSYIV VDLMVWWSIR TYINDFRKRK LNLAPIAYFS TYHGSISHLP 360 TGYMWSPHVV PKPSDWGPLV DVVGYCFLNL GSKYQPREEF LHWIERGSPP VYIGFGSMPL 420 DDPKQTMDII LETLKDTEQR GIVDRGWGGL GNLATEVPEN VFLVEDCPHD WLFPQCSAVV 480 HHGGAGTTAT GLKAGCPTTI VPFFGDQFFW GDRIYEKGLG PAPIPIAQLS VENLSSSIRF 540 MLQPEVKSQV MELAKVLENE DGVAAAVDAF HRHLPPELPL PESSSEKKDE DDRPDLLQWF 600 FIQIGKKCCL PCGGV* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| TIGR01426 | MGT | 2.0e-9 | 167 | 568 | 420 | + glycosyltransferase, MGT family. This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production [Cellular processes, Toxin production and resistance]. | ||
| COG1819 | COG1819 | 3.0e-37 | 155 | 572 | 427 | + Glycosyl transferases, related to UDP-glucuronosyltransferase [Carbohydrate transport and metabolism / Signal transduction mechanisms] | ||
| pfam03033 | Glyco_transf_28 | 2.0e-38 | 158 | 302 | 145 | + Glycosyltransferase family 28 N-terminal domain. The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). This N-terminal domain contains the acceptor binding site and likely membrane association site. This family also contains a large number of proteins that probably have quite distinct activities. | ||
| cd03784 | GT1_Gtf_like | 2.0e-129 | 157 | 573 | 417 | + This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0005773 | vacuole |
| GO:0005886 | plasma membrane |
| GO:0005975 | carbohydrate metabolic process |
| GO:0008152 | metabolic process |
| GO:0009813 | flavonoid biosynthetic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| EMBL | CBI18214.1 | 0 | 50 | 613 | 136 | 697 | unnamed protein product [Vitis vinifera] |
| RefSeq | NP_175027.1 | 0 | 1 | 615 | 1 | 615 | UDP-glucose:sterol glucosyltransferase, putative [Arabidopsis thaliana] |
| RefSeq | XP_002265312.1 | 0 | 50 | 613 | 120 | 681 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002302172.1 | 0 | 1 | 612 | 1 | 615 | predicted protein [Populus trichocarpa] |
| RefSeq | XP_002524293.1 | 0 | 48 | 612 | 14 | 577 | transferase, transferring glycosyl groups, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 3h4t_A | 3e-29 | 156 | 566 | 1 | 374 | A Chain A, Crystal Structure Of Medicago Truncatula Ugt71g1 |
| PDB | 3h4i_A | 3e-29 | 156 | 566 | 1 | 374 | A Chain A, Chimeric Glycosyltransferase For The Generation Of Novel Natural Products |
| PDB | 1iir_A | 2e-25 | 156 | 575 | 1 | 403 | A Chain A, Crystal Structure Of Udp-Glucosyltransferase Gtfb |
| PDB | 1rrv_B | 2e-23 | 156 | 557 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| PDB | 1rrv_A | 2e-23 | 156 | 557 | 1 | 383 | A Chain A, X-Ray Crystal Structure Of Tdp-Vancosaminyltransferase Gtfd As A Complex With Tdp And The Natural Substrate, Desvancosaminyl Vancomycin. |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO801427 | 438 | 185 | 615 | 0 |
| DT547914 | 323 | 174 | 496 | 0 |
| CO103793 | 276 | 169 | 444 | 0 |
| GT172550 | 304 | 137 | 440 | 0 |
| HO801427 | 191 | 156 | 345 | 7e-18 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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