| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G53770.2 |
| Family | GT68 |
| Protein Properties | Length: 602 Molecular Weight: 68316.9 Isoelectric Point: 8.012 |
| Chromosome | Chromosome/Scaffold: 1 Start: 20071311 End: 20073758 |
| Description | GDP-fucose protein-O-fucosyltransferase 2, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT68 | 239 | 579 | 0 |
| KRVLVIPSHRFDYHYSRIIDIDRINTCLGRTVVVSFEEFWKKDKNRKKHHHVHINRFICYFSKPEPCYVDKEHITKLKALGITVGGKLDTPWEEDIARPS NKTAEEVEANFRSDDDVIAIGDVFYANVEREWVMQPGGPVAHKCRTLIEPNRLILLTAQRFIQTFLGKNYIALHFRRHGFLKFWYDLFSTSLLHSTFDDN VVHFITKIKSGTLAKKFSWCASNAKNPSCFFPIPQAASCITRLIEKVEAPVLYLSTDAAESETGLLQSLLILNGKTVPLVKRPARDSAEKWDALLYRHGL EGDSQVEAMLDKTICALSSVFIGASGSTFTEDILRLRKDWG | |||
| Full Sequence |
|---|
| Protein Sequence Length: 602 Download |
| MVKVSSSTTS SSSSSSPDEE SDLQNLLEES DSQIDQFRIS DEAAEQRPTF DVESLRSRLR 60 RSFKLNLTKK QSIFIFLPIV IILIYLSTDF SNYFSVKVPN SAFRSNTLTG RVHESDLQAL 120 YLLRKQESDL FSIWNHTVSN LSTIDDVKSA VFRQISLNRQ IQNALLSPHK TGNVDIGGSS 180 DGYFAGGSCR KVDQKLNGRK TIQWKPRPDK FLFAICLSGQ MSNHLICLEK HMFFAALLKR 240 VLVIPSHRFD YHYSRIIDID RINTCLGRTV VVSFEEFWKK DKNRKKHHHV HINRFICYFS 300 KPEPCYVDKE HITKLKALGI TVGGKLDTPW EEDIARPSNK TAEEVEANFR SDDDVIAIGD 360 VFYANVEREW VMQPGGPVAH KCRTLIEPNR LILLTAQRFI QTFLGKNYIA LHFRRHGFLK 420 FWYDLFSTSL LHSTFDDNVV HFITKIKSGT LAKKFSWCAS NAKNPSCFFP IPQAASCITR 480 LIEKVEAPVL YLSTDAAESE TGLLQSLLIL NGKTVPLVKR PARDSAEKWD ALLYRHGLEG 540 DSQVEAMLDK TICALSSVFI GASGSTFTED ILRLRKDWGT ASECDEYLCA NEQPNFIADH 600 E* 660 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| pfam10250 | O-FucT | 0.005 | 234 | 309 | 86 | + GDP-fucose protein O-fucosyltransferase. This is a family of conserved proteins representing the enzyme responsible for adding O-fucose to EGF (epidermal growth factor-like) repeats. Six highly conserved cysteines are present in O-FucT-1 as well as a DXD-like motif (ERD), conserved in mammals, Drosophila, and C. elegans. Both features are characteristic of several glycosyltransferase families. The enzyme is a membrane-bound protein released by proteolysis and, as for most glycosyltransferases, is strongly activated by manganese. | ||
| cd11298 | O-FucT-2 | 0.003 | 404 | 568 | 165 | + GDP-fucose protein O-fucosyltransferase 2. O-FucT-2 adds O-fucose to thrombospondin type 1 repeats (TSRs), and appears conserved in bilateria. The O-fucosylation of TSRs appears to play a role in regulating secretion of metalloproteases of the ADAMTS superfamily. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 0.0006 | 211 | 252 | 42 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| cd11296 | O-FucT_like | 5.0e-14 | 378 | 575 | 205 | + GDP-fucose protein O-fucosyltransferase and related proteins. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003674 | molecular_function |
| GO:0005886 | plasma membrane |
| GO:0008150 | biological_process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAD50008.1 | 0 | 15 | 601 | 4 | 594 | AC007651_3 Hypothetical Protein [Arabidopsis thaliana] |
| DDBJ | BAF00786.1 | 0 | 1 | 601 | 1 | 563 | hypothetical protein [Arabidopsis thaliana] |
| RefSeq | NP_173170.2 | 0 | 15 | 601 | 4 | 564 | unknown protein [Arabidopsis thaliana] |
| RefSeq | NP_175780.1 | 0 | 1 | 601 | 1 | 563 | unknown protein [Arabidopsis thaliana] |
| RefSeq | XP_002264087.1 | 0 | 16 | 601 | 5 | 559 | PREDICTED: hypothetical protein [Vitis vinifera] |
