| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G60140.1 |
| Family | GT20 |
| Protein Properties | Length: 862 Molecular Weight: 97324.4 Isoelectric Point: 6.5994 |
| Chromosome | Chromosome/Scaffold: 1 Start: 22176934 End: 22180875 |
| Description | trehalose-6-phosphate synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 53 | 546 | 0 |
| ISLPCRERKIIVANFLPLNGKKDSETGKWKFSLDNDSPLLHLKDGFSPETEVIYVGSLKTHVDVSEQDEVSHNLFEEFNCVATFLPQDVHKKFYLGFCKQ QLWPLFHYMLPMCPDHGERFDRGLWQAYVSANKIFADKVMGVINLEEDYIWIHDYHLMVLPTFLRRRFHRVKLGFFLHSPFPSSEIYRTLPVREELLRGL LNCDLIGFHTFDYARHFLSCCCRMLGLEYESKRGHIALDYLGRTVFLKILPIGIHMGRLESVLNLPATAEKLKEIQEKYRGKKIILGVDDMDIFKGLSLK ILAFEHLLQQYPSMLGKIVLIQIVNPARGSGKDVQEARKETYDTVKRINERYGSHDYEPVVLIDRPVPRFEKSAYYALAECCIVNAVRDGMNLVPYKYTV CRQGTPSMNKSLGVSDDLPRTSTLVLSEFIGCSPSLSGAIRVNPWDVDAVADSLYSAITMSDFEKQLRHKKHFHYISTHDVGYWARSFSQDLER | |||
| Full Sequence |
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| Protein Sequence Length: 862 Download |
| MGSKSFGNLL DLASGDLLDI PQTPRYLPRV MTVPGIISDV DGYGISDGDS DVISLPCRER 60 KIIVANFLPL NGKKDSETGK WKFSLDNDSP LLHLKDGFSP ETEVIYVGSL KTHVDVSEQD 120 EVSHNLFEEF NCVATFLPQD VHKKFYLGFC KQQLWPLFHY MLPMCPDHGE RFDRGLWQAY 180 VSANKIFADK VMGVINLEED YIWIHDYHLM VLPTFLRRRF HRVKLGFFLH SPFPSSEIYR 240 TLPVREELLR GLLNCDLIGF HTFDYARHFL SCCCRMLGLE YESKRGHIAL DYLGRTVFLK 300 ILPIGIHMGR LESVLNLPAT AEKLKEIQEK YRGKKIILGV DDMDIFKGLS LKILAFEHLL 360 QQYPSMLGKI VLIQIVNPAR GSGKDVQEAR KETYDTVKRI NERYGSHDYE PVVLIDRPVP 420 RFEKSAYYAL AECCIVNAVR DGMNLVPYKY TVCRQGTPSM NKSLGVSDDL PRTSTLVLSE 480 FIGCSPSLSG AIRVNPWDVD AVADSLYSAI TMSDFEKQLR HKKHFHYIST HDVGYWARSF 540 SQDLERASRD HYSKRCWGVG WGLGFRLVAL SPNFRRLSIE QTVSAYRRSS KRAIFLDYDG 600 TLVPETSIVK DPSAEVISAL KALCSDPNNT IFIVSGRGKV SLSEWLAPCE NLGIAAEHGY 660 FTRWNKSSDW ETSGLSDDLE WKKVVEPIMR LYTETTDGSN IEAKESALVW HHQDADPDFG 720 SCQAKELLDH LETVLVNEPV IVNRGHQIVE VKPQGVSKGL VTGKILSRML EDGIAPDFVV 780 CIGDDRSDEE MFENISTTLS AQSSSMSTEI FACTVGRKPS KAKYFLDEVS DVVKLLQGLA 840 NTSSPKPRYP SHLRVSFESV V* 900 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| PLN03063 | PLN03063 | 1.0e-162 | 58 | 840 | 821 | + alpha,alpha-trehalose-phosphate synthase (UDP-forming); Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 843 | 852 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 59 | 546 | 492 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| PRK14501 | PRK14501 | 0 | 117 | 840 | 731 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| cd03788 | GT1_TPS | 0 | 62 | 545 | 484 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0004805 | trehalose-phosphatase activity |
| GO:0005575 | cellular_component |
| GO:0005992 | trehalose biosynthetic process |
| GO:0008152 | metabolic process |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| DDBJ | BAF01061.1 | 0 | 1 | 861 | 1 | 861 | putative trehalose-6-phosphate synthase [Arabidopsis thaliana] |
| EMBL | CAN78769.1 | 0 | 1 | 861 | 1 | 857 | hypothetical protein [Vitis vinifera] |
| RefSeq | NP_176221.1 | 0 | 1 | 861 | 1 | 861 | ATTPS10 (trehalose phosphate synthase); transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002264873.1 | 0 | 1 | 848 | 1 | 844 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002521023.1 | 0 | 1 | 861 | 1 | 861 | trehalose-6-phosphate synthase, putative [Ricinus communis] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 2wtx_D | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_C | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_B | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 2wtx_A | 0 | 144 | 546 | 75 | 453 | A Chain A, Insight Into The Mechanism Of Enzymatic Glycosyltransfer With Retention Through The Synthesis And Analysis Of Bisubstrate Glycomimetics Of Trehalose-6-Phosphate Synthase |
| PDB | 1gz5_D | 0 | 144 | 546 | 74 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 778 | 70 | 843 | 0 |
| HO779327 | 515 | 99 | 613 | 0 |
| HO779327 | 253 | 610 | 862 | 0 |
| JZ151866 | 332 | 402 | 733 | 0 |
| HO777775 | 78 | 1 | 77 | 0.099 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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