| Basic Information | |
|---|---|
| Species | Arabidopsis thaliana |
| Cazyme ID | AT1G68020.1 |
| Family | GT20 |
| Protein Properties | Length: 701 Molecular Weight: 80069.3 Isoelectric Point: 8.0687 |
| Chromosome | Chromosome/Scaffold: 1 Start: 25497290 End: 25500374 |
| Description | trehalose synthase, putative, expressed |
| View CDS | |
| Signature Domain Download full data set without filtering | |||
|---|---|---|---|
| Family | Start | End | Evalue |
| GT20 | 44 | 557 | 0 |
| SKDTDLSPKDRIIIVANELPIRAQRRVDGNGSGSSSSSTCCSKGWNFSWDENSLLLQLKDGLGDEAIEVIYVGCLKEEIPLNEQEEVYQILLESFKCVPT FLPLDLYTRYYHGFCKQQLWPLFHYMLPLSPDLGGRFDRTLWQAYVSVNKIFADRIMEVINPEDDFVWIHDYHLMVLPTFLRKRFNRVKLGFFLHSPFPS SEIYKTLPIREELLRALLNSDLIGFHTFDYARHFLSCCSRMLGLTYESKRGYIGLEYYGRTVSIKILPVGIHMGQLQSVLSLPETERKVGELIERYGRKG RTMLLGVDDMDIFKGITLKLLAMEQLLMQHPEWQGKVVLVQIANPARGKGKDVKEMQAETYSTVKRINETFGRPGYDPIVLIDAPLKFYERVAYYVVAEC CLVTAVRDGMNLIPYEYIVSRQGNEKLDKILKLEANNRNKKSMLVVSEFIGCSPSLSGAIRVNPWNVDAVADAMDSALEVAEPEKQLRHEKHYKYVSTHD VGYWARSFLQDLER | |||
| Full Sequence |
|---|
| Protein Sequence Length: 701 Download |
| MVSRSYSNLL ELASGDSPTF GRMNRQIPRI MAVAGIMSNI DNDSKDTDLS PKDRIIIVAN 60 ELPIRAQRRV DGNGSGSSSS STCCSKGWNF SWDENSLLLQ LKDGLGDEAI EVIYVGCLKE 120 EIPLNEQEEV YQILLESFKC VPTFLPLDLY TRYYHGFCKQ QLWPLFHYML PLSPDLGGRF 180 DRTLWQAYVS VNKIFADRIM EVINPEDDFV WIHDYHLMVL PTFLRKRFNR VKLGFFLHSP 240 FPSSEIYKTL PIREELLRAL LNSDLIGFHT FDYARHFLSC CSRMLGLTYE SKRGYIGLEY 300 YGRTVSIKIL PVGIHMGQLQ SVLSLPETER KVGELIERYG RKGRTMLLGV DDMDIFKGIT 360 LKLLAMEQLL MQHPEWQGKV VLVQIANPAR GKGKDVKEMQ AETYSTVKRI NETFGRPGYD 420 PIVLIDAPLK FYERVAYYVV AECCLVTAVR DGMNLIPYEY IVSRQGNEKL DKILKLEANN 480 RNKKSMLVVS EFIGCSPSLS GAIRVNPWNV DAVADAMDSA LEVAEPEKQL RHEKHYKYVS 540 THDVGYWARS FLQDLERSCG EHGRRRCWGI GFGLSFRVVA LDQSFRKLSM EHIVSAYKRT 600 KTRAILLDYD DTLMPQGSID KRPSSKSIDI LNTLCRDKGN LVFIVSAKSR ETLSDWFSPC 660 EKLGIAAEHG YFLRYSTKTF YFLALPLYLI TQAPSNYYTG * 720 |
| Functional Domains Download unfiltered results here | ||||||||
|---|---|---|---|---|---|---|---|---|
| Cdd ID | Domain | E-Value | Start | End | Length | Domain Description | ||
| COG0380 | OtsA | 6.0e-145 | 38 | 558 | 523 | + Trehalose-6-phosphate synthase [Carbohydrate transport and metabolism] | ||
| PRK14501 | PRK14501 | 2.0e-146 | 54 | 674 | 627 | + putative bifunctional trehalose-6-phosphate synthase/HAD hydrolase subfamily IIB; Provisional | ||
| PLN02205 | PLN02205 | 0 | 1 | 674 | 681 | + alpha,alpha-trehalose-phosphate synthase [UDP-forming] | ||
| pfam00982 | Glyco_transf_20 | 0 | 54 | 557 | 507 | + Glycosyltransferase family 20. Members of this family belong to glycosyl transferase family 20. OtsA (Trehalose-6-phosphate synthase) is homologous to regions in the subunits of yeast trehalose-6-phosphate synthase/phosphate complex. | ||
| cd03788 | GT1_TPS | 0 | 54 | 556 | 503 | + Trehalose-6-Phosphate Synthase (TPS) is a glycosyltransferase that catalyses the synthesis of alpha,alpha-1,1-trehalose-6-phosphate from glucose-6-phosphate using a UDP-glucose donor. It is a key enzyme in the trehalose synthesis pathway. Trehalose is a nonreducing disaccharide present in a wide variety of organisms and may serve as a source of energy and carbon. It is characterized most notably in insect, plant, and microbial cells. Its production is often associated with a variety of stress conditions, including desiccation, dehydration, heat, cold, and oxidation. This family represents the catalytic domain of the TPS. Some members of this domain family coexist with a C-terminal trehalose phosphatase domain. | ||
| Gene Ontology | |
|---|---|
| GO Term | Description |
| GO:0003824 | catalytic activity |
| GO:0003825 | alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity |
| GO:0004805 | trehalose-phosphatase activity |
| GO:0005992 | trehalose biosynthetic process |
| GO:0016757 | transferase activity, transferring glycosyl groups |
| Annotations - NR Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| GenBank | AAG52003.1 | 0 | 1 | 674 | 1 | 661 | AC012563_13 putative trehalose-6-phosphate synthase; 46897-44149 [Arabidopsis thaliana] |
| RefSeq | NP_564918.1 | 0 | 1 | 700 | 1 | 700 | ATTPS6; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | NP_974105.1 | 0 | 1 | 674 | 1 | 674 | ATTPS6; alpha,alpha-trehalose-phosphate synthase (UDP-forming)/ transferase, transferring glycosyl groups / trehalose-phosphatase [Arabidopsis thaliana] |
| RefSeq | XP_002284972.1 | 0 | 1 | 674 | 1 | 668 | PREDICTED: hypothetical protein [Vitis vinifera] |
| RefSeq | XP_002312472.1 | 0 | 1 | 687 | 1 | 681 | predicted protein [Populus trichocarpa] |
| Annotations - PDB Download unfiltered results here | |||||||
|---|---|---|---|---|---|---|---|
| Source | Hit ID | E-Value | Query Start | Query End | Hit Start | Hit End | Description |
| PDB | 1gz5_D | 0 | 153 | 557 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_C | 0 | 153 | 557 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_B | 0 | 153 | 557 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1gz5_A | 0 | 153 | 557 | 75 | 452 | A Chain A, Trehalose-6-Phosphate Synthase. Otsa |
| PDB | 1uqu_B | 0 | 153 | 557 | 76 | 453 | A Chain A, Trehalose-6-Phosphate From E. Coli Bound With Udp-Glucose. |
| Metabolic Pathways | |||
|---|---|---|---|
| Pathway Name | Reaction | EC | Protein Name |
| trehalose biosynthesis I | TREHALOSE6PSYN-RXN | EC-2.4.1.15 | α,α-trehalose-phosphate synthase (UDP-forming) |
| Hydropathy |
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| EST Download unfiltered results here | ||||
|---|---|---|---|---|
| Hit | Length | Start | End | EValue |
| HO777775 | 588 | 88 | 674 | 0 |
| HO779327 | 516 | 111 | 626 | 0 |
| HO798827 | 343 | 52 | 394 | 0 |
| HO777775 | 76 | 1 | 69 | 0.0000000000002 |
| HO779327 | 62 | 620 | 681 | 0.00000000004 |
| Sequence Alignments (This image is cropped. Click for full image.) |
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